Autoimmune disease Clinical Trials in Philadelphia, PA

As of June 2026, 51 paid clinical trials are recruiting for Autoimmune disease in Philadelphia, Pennsylvania. Autoimmune disease research covers a broad spectrum of immune-modulating therapies — JAK inhibitors, biologics, T-cell modulators, and tolerance-inducing agents — across rheumatologic, dermatologic, neurologic, and GI conditions. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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51 clinical trials for Autoimmune disease

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Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

for Multiple Sclerosis

12 locations incl. New Haven

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55

Code: NCT05285891·Phase 4·Recruiting

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A Study of Nipocalimab in Children Aged 2 to Less Than 18 Years With Generalized Myasthenia Gravis

for Myasthenia Gravis

Drug: Nipocalimab

11 locations incl. Phoenix

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 2 - 17

Code: NCT05265273·Phase 2, Phase 3·Recruiting

Apply to this trial

Immune Profiles in Multiple Sclerosis (MS) Patients and Healthy Volunteers Through Thoracic Duct Cannulation

for Multiple Sclerosis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT05162638·Enrolling By Invitation

Study of SFA002 in Patients with Mild to Moderate Psoriasis Plaques

for Psoriasis

3 locations incl. Pompano Beach

Sponsor: SFA Therapeutics

Sex: All·Age: 18+

Code: NCT05642182·Phase 1·Recruiting

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X-linked Moesin Associated Immunodeficiency

for Immune Deficiency

3 locations incl. Bethesda

Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

Sex: Male·Age: 4 - 80

Code: NCT06278337·Recruiting

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A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

for Ulcerative Colitis

11 locations incl. San Francisco

Sponsor: Eli Lilly and Company

Sex: All·Age: 2 - 19

Code: NCT04844606·Phase 3·Recruiting

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Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

for Generalized Myasthenia Gravis

32 locations incl. Birmingham

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT04202341·Recruiting

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

51 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting

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Physiological Effects of N-Acetyl Cysteine in Patients With Multiple Sclerosis

for Multiple Sclerosis

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT03032601·Enrolling By Invitation

Fecal Microbiome Transplant

for Clostridium Difficile

1 location in Philadelphia

Sponsor: Judith Kelsen

Sex: All·Age: 3 - 21

Code: NCT02636517·Phase 1·Enrolling By Invitation

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

142 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting

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Conditions in Autoimmune disease (Philadelphia, PA)

Crohn's disease· 15 Ulcerative colitis· 9 Atopic dermatitis / eczema· 8 Multiple sclerosis· 6 Myasthenia gravis· 6 Lupus (SLE)· 5 Psoriatic arthritis· 4 Inflammatory bowel disease (IBD)· 4 Hidradenitis suppurativa· 3 Autoimmune diseases (general)· 3 Psoriasis· 2 Rheumatoid arthritis· 1