Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,661 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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3,661 clinical trials

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A Phase IIb Ensifentrine-glycopyrrolate Fixed-dose Combination Dose Ranging Study in Subjects With COPD

for Chronic Obstructive Pulmonary Disease

57 locations incl. Dothan

Sponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA

Sex: All·Age: 40 - 80

Code: NCT07016412·Phase 2·Recruiting

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A Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia Areata

for Severe Alopecia Areata

Drug: Ritlecitinib

29 locations incl. Encinitas

Sponsor: Pfizer

Sex: All·Age: 6 - 11

Code: NCT07029711·Phase 3·Recruiting

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A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)

for Human Immunodeficiency Virus (HIV)

23 locations incl. Birmingham

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT07044297·Phase 3·Recruiting

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AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

for KRAS Altered Advanced or Metastatic Solid Tumors

10 locations incl. Duarte

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT07094113·Phase 1·Recruiting

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A Study of Tarlatamab for People With Prostate Cancer

for Metastatic Prostate Cancer

Drug: Tarlatamab

10 locations incl. San Diego

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Male·Age: 18+

Code: NCT07111507·Phase 2·Recruiting

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Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

for Esophageal Squamous Cell Carcinoma

1 location in Pittsburgh

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06780111·Phase 1, Phase 2·Recruiting

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AuriculoTherapy NeuroImaging

for Low Back Pain

1 location in Pittsburgh

Sponsor: Keith M Vogt

Sex: All·Age: 18+

Code: NCT06825390·Recruiting

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Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

for Astrocytoma, IDH-Mutant, Grade 2

42 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06860594·Phase 1·Recruiting

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

for Macular Edema Secondary to Inflammation

55 locations incl. Phoenix

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06990399·Phase 3·Recruiting

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RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

for Adjustment Disorder

30 locations incl. Birmingham

Sponsor: Reunion Neuroscience Inc

Sex: All·Age: 18 - 80

Code: NCT07002034·Phase 2·Recruiting

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An Individual Patient, Open Label Study to Use ACER-001 to Treat Combined D,L-2 Hydroxyglutaric Aciduria (C-2HGA)

for Combined D,L-2-hydroxyglutaric Aciduria

1 location in Pittsburgh

Sponsor: Jerry Vockley, MD, PhD

Sex: Male·Age: All ages

Code: NCT07125066·Phase 1·Enrolling By Invitation

A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)

for Geographic Atrophy Secondary to Age-related Macular Degeneration

6 locations incl. Mountain View

Sponsor: Complement Therapeutics

Sex: All·Age: 55+

Code: NCT07144137·Recruiting

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A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

for Melanoma

6 locations incl. Grand Rapids

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07115043·Phase 1, Phase 2·Recruiting

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PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis

for End Stage Renal Disease

7 locations incl. Washington D.C.

Sponsor: Merit Medical Systems, Inc.

Sex: All·Age: 18+

Code: NCT06422871·Recruiting

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A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

for Ulcerative Colitis

Drug: Risankizumab

11 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 2 - 17

Code: NCT07071519·Phase 3·Recruiting

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Global Open-Label Extension Study of Del-desiran for the Treatment of DM1

for Myotonic Dystrophy Type 1

17 locations incl. Los Angeles

Sponsor: Avidity Biosciences, Inc.

Sex: All·Age: 16+

Code: NCT07008469·Phase 3·Enrolling By Invitation

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

for Atherosclerotic Cardiovascular Disease

139 locations incl. Daphne

Sponsor: Amgen

Sex: All·Age: 45 - 99

Code: NCT07037433·Phase 3·Recruiting

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Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

for Acute Ischemic Stroke

15 locations incl. Tucson

Sponsor: Pharmazz, Inc.

Sex: All·Age: 18 - 80

Code: NCT05691244·Phase 3·Recruiting

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Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

for Breast Cancer

22 locations incl. Duarte

Sponsor: Celcuity Inc

Sex: All·Age: 18+

Code: NCT06757634·Phase 3·Recruiting

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Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

for Percutaneous Coronary Intervention

Drug: Inclisiran

102 locations incl. Alexander City

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06909565·Phase 4·Recruiting

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Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

for Pulmonary Hypertension

25 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT06911632·Recruiting

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Identification of Breast Cancer in Breath Samples Using Trained Detection Dogs

for Breast Cancer

2 locations incl. Totowa

Sponsor: SpotitEarly

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07038785·Recruiting

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Study of Lenacapavir as a Once-Yearly Injection for HIV Pre-exposure Prophylaxis (PrEP)

for HIV Pre-exposure Prophylaxis

31 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT07047716·Phase 3·Recruiting

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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

for Diabetes Mellitus, Type 2

Drug: Empagliflozin

216 locations incl. Anniston

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07064473·Phase 3·Recruiting

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Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

for Neovascular Age-Related Macular Degeneration (nAMD)

54 locations incl. Scottsdale

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 50+

Code: NCT07064759·Phase 3·Recruiting

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A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer

for Ovarian Cancer

14 locations incl. Augusta

Sponsor: Compugen Ltd

Sex: Female·Age: 18+

Code: NCT06888921·Phase 1, Phase 2·Recruiting

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Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

for Pancreatic Neuroendocrine Tumor (pNET)

39 locations incl. Birmingham

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT06943755·Phase 2, Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

for Alzheimer's Disease

Drug: KarXT

30 locations incl. Fullerton

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 60 - 85

Code: NCT06976203·Phase 3·Recruiting

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A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

for Breast Neoplasms

33 locations incl. Daphne

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07060807·Phase 3·Recruiting

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Mindfulness Training and Respiration Biosignal Feedback - Study 2

for Psychological Distress

1 location in Pittsburgh

Sponsor: Equa Health

Sex: All·Age: 18 - 30

Code: NCT07136948·Recruiting

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Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

for Renal Cell Carcinoma

7 locations incl. San Francisco

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 120

Code: NCT07049926·Phase 1, Phase 2·Recruiting

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Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

for Acute Myeloid Leukemia

9 locations incl. Baltimore

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06824168·Phase 2·Recruiting

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Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

for Familial Adenomatous Polyposis (FAP)

18 locations incl. Arcadia

Sponsor: Rapamycin Holdings Inc.

Sex: All·Age: 18+

Code: NCT06950385·Phase 3·Recruiting

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CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy

for Glioblastoma

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06973096·Phase 1·Recruiting

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Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

for Non-small Cell Lung Cancer

22 locations incl. Glendale

Sponsor: Nuvalent Inc.

Sex: All·Age: 18+

Code: NCT06765109·Phase 3·Recruiting

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The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis

for Atopic Dermatitis (AD)

2 locations incl. Pittsburgh

Sponsor: Daniel Kaplan

Sex: All·Age: 18+

Code: NCT06928246·Phase 1·Recruiting

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Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

for Recurrent Non-Muscle Invasive Bladder Carcinoma

56 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07000084·Phase 3·Recruiting

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A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma

for Gastroesophageal Adenocarcinoma

7 locations incl. Newark

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07069712·Phase 2·Recruiting

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Impact of Prehabilitation in Oncology Via Exercise- Esophageal (IMPROVE-Esophageal)

for Esophageal Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06872515·Recruiting

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A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias

for High-risk Myelodysplastic Syndrome

11 locations incl. Duarte

Sponsor: Crossbow Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT06994676·Phase 1·Recruiting

Apply to this trial