Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,661 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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3,661 clinical trials

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Optimal Ventilation for Cardiac Arrest

for Cardiac Arrest (CA)

20 locations incl. Orange

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 37 Weeks - 18

Code: NCT07114510·Recruiting

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FTT PET/CT in Pancreatic Neuroendocrine Tumors

for Neuroendocrine Carcinoma Metastatic

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT07114939·Phase 1·Recruiting

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Study of COYA 302 for the Treatment of ALS

for Amyotrophic Lateral Sclerosis (ALS)

21 locations incl. Phoenix

Sponsor: Coya Therapeutics

Sex: All·Age: 18 - 80

Code: NCT07161999·Phase 2·Recruiting

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A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)

for Pulmonary Arterial Hypertension (PAH)

10 locations incl. Phoenix

Sponsor: AllRock Bio, Inc.

Sex: All·Age: 18+

Code: NCT07175038·Phase 2·Recruiting

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CGM Adherence Compared to Finger-stick Glucose Monitoring in Pregnancies With Type 2 Pregestational Diabetes

for Type 2 Diabetes Mellitus (T2DM)

2 locations incl. Sewell

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+

Code: NCT07184775·Recruiting

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An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: Duvakitug

93 locations incl. Peoria

Sponsor: Sanofi

Sex: All·Age: 16 - 80

Code: NCT07184931·Phase 3·Recruiting

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A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

for Colitis, Ulcerative

54 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 12+

Code: NCT07196748·Phase 3·Recruiting

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A Long-Term Study of Navenibart in Participants With Hereditary Angioedema

for Hereditary Angioedema (HAE)

Drug: navenibart

10 locations incl. Scottsdale

Sponsor: Astria Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT07204938·Phase 3·Enrolling By Invitation

Acetazolamide in Central Sleep Apnea Patients Using Medication for Opioid Use Disorder

for Central Sleep Apnea Comorbid With Opioid Use

1 location in Pittsburgh

Sponsor: Sanjay R Patel

Sex: All·Age: 18 - 100

Code: NCT06521476·Phase 2·Recruiting

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Physical Activity in CKD

for Chronic Kidney Diseases

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 13 - 18

Code: NCT06624358·Recruiting

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Circulating Tumor DNA

for ER+ Breast Cancer

7 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06923527·Phase 2·Recruiting

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A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma

for Relapsed or Refractory Multiple Myeloma

10 locations incl. Birmingham

Sponsor: ModernaTX, Inc.

Sex: All·Age: 18+

Code: NCT07116616·Phase 1, Phase 2·Recruiting

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A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

for Urinary Incontinence,Stress

Drug: Orforglipron

21 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: Female·Age: 18+

Code: NCT07202884·Phase 3·Recruiting

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Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder

for Bipolar I or II Disorder

47 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT07220460·Phase 2·Recruiting

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Rehabilitation Strategies for Social Participation in Chronic Stroke Survivors

for Stroke

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06758505·Recruiting

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RELIVE (Randomized Evaluation of Less Invasive Ventricular Enhancement) Trial

for Left Ventricle Remodeling

6 locations incl. Phoenix

Sponsor: BioVentrix

Sex: All·Age: 18+

Code: NCT06813820·Recruiting

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A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

for Colon Cancer

14 locations incl. Denver

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT07011576·Phase 2·Recruiting

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A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

for Non-small Cell Carcinoma

133 locations incl. Alabaster

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07144280·Phase 3·Recruiting

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AI-informed Colorectal Cancer (CRC) Screening Navigation vs. Standard of Care Among Screening-naive Penn Medicine Patients 45-49 Years Old to Increase CRC Screening Uptake

for Colorectal Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 45 - 49

Code: NCT07230795·Enrolling By Invitation

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

for Metastatic Castration Sensitive Prostate Cancer (mCSPC)

Drug: Mevrometostat

120 locations incl. Huntsville

Sponsor: Pfizer

Sex: Male·Age: 18+

Code: NCT07028853·Phase 3·Recruiting

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Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors

for Somatostatin Receptor Positive

2 locations incl. Philadelphia

Sponsor: ITM Solucin GmbH

Sex: All·Age: 24 Months - 18

Code: NCT06441331·Phase 1·Recruiting

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Real-Time Diagnosis of Life-Threatening Necrotizing Soft Tissue Infections (NSTI) Using Indocyanine Green (ICG) Kinetic Modeling

for Necrotizing Fascitis

8 locations incl. Los Angeles

Sponsor: Eric R. Henderson

Sex: All·Age: 18+

Code: NCT06877793·Recruiting

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Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

for Acute Myeloid Leukemia (AML)

42 locations incl. Gilbert

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT07007312·Phase 3·Recruiting

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Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

for Urothelial Cancer

38 locations incl. Fullerton

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT07129993·Phase 2, Phase 3·Recruiting

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A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

for Radiographic Axial Spondyloarthritis

Drug: Tulisokibart

33 locations incl. Chandler

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 80

Code: NCT07133633·Phase 2·Recruiting

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Examining the Efficacy of the PRAISE With Coaching Program

for Aggression Childhood

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 8+·Accepts healthy volunteers

Code: NCT07191782·Recruiting

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MethaLoad Dose-Finding Study

for Opioid Use Disorder (OUD)

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06877858·Phase 1·Recruiting

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A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza

for Influenza

120 locations incl. Anniston

Sponsor: Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Sex: All·Age: 12+

Code: NCT07159763·Phase 3·Recruiting

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Adaptive Radiation Therapy for Men With Intermediate- or High-Risk Prostate Cancer

for Prostate Cancer (Adenocarcinoma)

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: Male·Age: 18+

Code: NCT07219303·Recruiting

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Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study

for Heavy Menstrual Bleeding

9 locations incl. Palo Alto

Sponsor: Oregon Health and Science University

Sex: Female·Age: 10 - 24

Code: NCT05916469·Recruiting

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Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).

for Juvenile Psoriatic Arthritis

Drug: Secukinumab

8 locations incl. Gainesville

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 2 - 17

Code: NCT06751238·Phase 1·Recruiting

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A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

for Hypothalamic Obesity

8 locations incl. Birmingham

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 4+

Code: NCT06760546·Phase 3·Recruiting

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A Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors

for Advanced/Metastatic Solid Tumors

5 locations incl. Los Angeles

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT07141706·Phase 1·Recruiting

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Circulating Tumor DNA in High Risk Localized Prostate Cancer

for Prostate Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Male·Age: 18+

Code: NCT07222436·Recruiting

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GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections

for Aortic Dissection

16 locations incl. Birmingham

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06827990·Recruiting

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9-ING-41 Combined With Retifanlimab, Plus Modified FOLFIRINOX for Patients With Advanced Pancreatic Adenocarcinoma (RiLEY)

for Pancreatic Adenocarcinoma

Drug: Retifanlimab

1 location in Pittsburgh

Sponsor: Anwaar Saeed

Sex: All·Age: 18+

Code: NCT06896188·Phase 1·Recruiting

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A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

for Chronic Obstructive Pulmonary Disease

Drug: Dupilumab

10 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 40 - 85

Code: NCT07053423·Phase 4·Recruiting

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Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

for Plaque Psoriasis

Drug: Deucravacitinib

122 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 40+

Code: NCT07116967·Phase 3·Recruiting

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Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

for High Risk Cardiovascular Disease

Drug: Zilebesiran

257 locations incl. Birmingham

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07181109·Phase 3·Recruiting

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Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder

for Social Anxiety Disorder (SAD)

30 locations incl. Phoenix

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07221578·Phase 3·Recruiting

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