Heart disease Clinical Trials in New York, NY

As of June 2026, 123 paid clinical trials are recruiting for Heart disease in New York, New York. Heart disease research tests new drug therapies, device-based interventions, and lifestyle programs for heart failure, atrial fibrillation, hypertension, and coronary disease — including therapies that reduce hospitalization and cardiovascular death. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Facility

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

123 clinical trials for Heart disease

·Clear filters·↓ Download CSV

A Pilot Feasibility and Acceptability Study of Remote ExerciSe Training mOdalities (PRESTO)

for Cardiovascular Diseases

1 location in New York

Sponsor: NYU Langone Health

Sex: All·Age: 45+

Code: NCT06931470·Recruiting

Apply to this trial

Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure

for Atrial Fibrillation (AF)

6 locations incl. Hartford

Sponsor: McMaster University

Sex: All·Age: 18+

Code: NCT06957366·Recruiting

Apply to this trial

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

for Heart Failure

Drug: Dapagliflozin

194 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT06677060·Phase 3·Recruiting

Apply to this trial

Alleviant ALLAY-HFrEF Study

for Heart Failure

35 locations incl. Los Angeles

Sponsor: Alleviant Medical, Inc.

Sex: All·Age: 18+

Code: NCT06812533·Enrolling By Invitation

Prevail Global Study

for Coronary Artery Disease

51 locations incl. Birmingham

Sponsor: Medtronic Vascular

Sex: All·Age: 18+

Code: NCT06535854·Recruiting

Apply to this trial

Partners in Control, Phase II: Using Remote Monitoring Technology With Community Health Workers to Support Hypertension Management for Latinx Patients

for Hypertension

1 location in New York

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT06730230·Recruiting

Apply to this trial

The Sleep2BWell Trial

for Blood Pressure

2 locations incl. New York

Sponsor: Columbia University

Sex: All·Age: 20+·Accepts healthy volunteers

Code: NCT06565104·Recruiting

Apply to this trial

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

for Heart Failure

88 locations incl. Alexander City

Sponsor: Cytokinetics

Sex: All·Age: 18 - 85

Code: NCT06736574·Phase 3·Recruiting

Apply to this trial

Subspecialty Ambulatory Quality Cardiology Program

for Heart Failure With Reduced Ejection Fraction

1 location in New York

Sponsor: NYU Langone Health

Sex: All·Age: 18 - 90

Code: NCT07283666·Enrolling By Invitation

The CardioClip Study

for Heart Failure With Reduced Ejection Fraction

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18 - 90

Code: NCT06241430·Recruiting

Apply to this trial

Assessment of Safety and Accuracy of the Microtech System in Patients Undergoing Left Ventricular Assist Device Implantation

for Heart Failure

1 location in New York

Sponsor: Microtech Medical Technologies, Ltd

Sex: All·Age: All ages

Code: NCT06682910·Recruiting

Apply to this trial

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for Heart Failure

57 locations incl. Phoenix

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06526195·Recruiting

Apply to this trial

Impella Reverse Remodeling in End-Stage Heart Failure

for Heart Failure

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06800716·Recruiting

Apply to this trial

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

for Ventricular Ejection Fraction

8 locations incl. Orange

Sponsor: Peerbridge Health, Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06699056·Recruiting

Apply to this trial

Scaling Telehealth Models to Improve Co-morbid Diabetes and Hypertension in Immigrant Populations (Phase II)

for Diabetes Mellitus Type II

1 location in New York

Sponsor: NYU Langone Health

Sex: All·Age: 21+

Code: NCT06542939·Enrolling By Invitation

PULSED AF Post-Approval Study

for Atrial Fibrillation

18 locations incl. Tampa

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18+

Code: NCT06578104·Recruiting

Apply to this trial

Skin Pigment/Pulse Oximeter in Congenital Heart Disease (CHD)

for Hypoxemia

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: Up to 18

Code: NCT06575270·Recruiting

Apply to this trial

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

for Cardiovascular Diseases

37 locations incl. Little Rock

Sponsor: BrioHealth Solutions, Inc.

Sex: All·Age: 18 - 100

Code: NCT06310031·Recruiting

Apply to this trial

Pericardiotomy in Cardiac Surgery

for Atrial Fibrillation

1 location in New York

Sponsor: Population Health Research Institute

Sex: All·Age: 18+

Code: NCT06486636·Recruiting

Apply to this trial

THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

for Hypertension

33 locations incl. Birmingham

Sponsor: SoniVie Inc.

Sex: All·Age: 22 - 75

Code: NCT06559891·Recruiting

Apply to this trial

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities

for Coronary Artery Disease

18 locations incl. Glendale

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18+

Code: NCT06399705·Phase 3·Recruiting

Apply to this trial

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women

for Coronary Artery Disease

18 locations incl. Glendale

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18+

Code: NCT06399692·Phase 3·Recruiting

Apply to this trial

The TRICURE EFS Study

for Tricuspid Valve Regurgitation

8 locations incl. Atlanta

Sponsor: TRiCares

Sex: All·Age: 18+

Code: NCT06506942·Recruiting

Apply to this trial

A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)

for Pulmonary Hypertension

31 locations incl. Phoenix

Sponsor: Tectonic Therapeutic

Sex: All·Age: 18 - 83

Code: NCT06616974·Phase 2·Recruiting

Apply to this trial

PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm

for Coronary Artery Disease

18 locations incl. Chandler

Sponsor: Kardion Inc

Sex: All·Age: 18 - 90

Code: NCT06445608·Recruiting

Apply to this trial

Abbott Structural Heart Device Registry

for Heart Diseases

5 locations incl. New Brunswick

Sponsor: Abbott Medical Devices

Sex: All·Age: All ages

Code: NCT06590467·Recruiting

Apply to this trial

Global Paradise System US Post Approval Study

for Hypertension

39 locations incl. Sacramento

Sponsor: ReCor Medical, Inc.

Sex: All·Age: 18+

Code: NCT06297291·Recruiting

Apply to this trial

A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)

for Atrial Fibrillation

43 locations incl. Phoenix

Sponsor: Biosense Webster, Inc.

Sex: All·Age: 18 - 80

Code: NCT06455098·Recruiting

Apply to this trial

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

for Heart Failure

Drug: Empagliflozin

95 locations incl. Mobile

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06424288·Phase 3·Recruiting

Apply to this trial

Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

for Intracerebral Hemorrhage

13 locations incl. Irvine

Sponsor: Zeenat Qureshi Stroke Institute

Sex: All·Age: 18 - 100

Code: NCT06402968·Recruiting

Apply to this trial

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

for In-Stent Restenosis

28 locations incl. Birmingham

Sponsor: Concept Medical Inc.

Sex: All·Age: 18 - 110

Code: NCT05908331·Recruiting

Apply to this trial

A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation

for Heart Failure

Drug: Ziltivekimab

41 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT06200207·Phase 3·Recruiting

Apply to this trial

Clinical and Healthcare Outcomes From Real-World Use in the United States of a Companion AI During AF Ablation

for Atrial Fibrillation

4 locations incl. Evanston

Sponsor: Volta Medical

Sex: All·Age: 21+

Code: NCT06056271·Recruiting

Apply to this trial

The DREAM Study: A Multidimensional Sleep Health Intervention for Improving Cardiometabolic Health

for Blood Pressure

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT06285968·Recruiting

Apply to this trial

A Preliminary Study for INFORMED

for Heart Failure

1 location in New York

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 65+

Code: NCT05585125·Phase 4·Enrolling By Invitation

N-of-1 for Beta-Blockers in Cardiac Amyloidosis

for Cardiac Amyloidosis

1 location in New York

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 65+

Code: NCT05019027·Phase 4·Enrolling By Invitation

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

for Hypertension

70 locations incl. Scottsdale

Sponsor: Orchestra BioMed, Inc

Sex: All·Age: 18+

Code: NCT06059638·Recruiting

Apply to this trial

Reducing AIR Pollution Exposure to Lower Blood PRESSURE Among New York City Public Housing Residents

for Blood Pressure

1 location in New York

Sponsor: NYU Langone Health

Sex: All·Age: 18 - 100

Code: NCT05874479·Recruiting

Apply to this trial

Safety and Effectiveness of Pulmonary Vein isOLation And posterioR Wall Ablation wIth pulSed Field Energy in Patients With Paroxysmal and Persistent AF

for Atrial Fibrillation

6 locations incl. Jonesboro

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 80

Code: NCT06099730·Recruiting

Apply to this trial

The Fourth Left Atrial Appendage Occlusion Study

for Atrial Fibrillation

51 locations incl. Birmingham

Sponsor: Hamilton Health Sciences Corporation

Sex: All·Age: 18+

Code: NCT05963698·Recruiting

Apply to this trial

Conditions in Heart disease (New York, NY)

Heart failure· 44 Cardiovascular disease (general)· 29 Coronary artery disease· 21 Atrial fibrillation· 20 Hypertension (high blood pressure)· 19 Congenital heart disease· 6 Myocardial infarction (heart attack)· 3