Paid Clinical Trials in North Carolina

North Carolina has 2,944 paid clinical trials enrolling now across cities including Durham, Chapel Hill and Winston-Salem. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in North Carolina include Duke University Medical Center, UNC Health and Wake Forest Baptist, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,944 clinical trials

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RIC (Remote Ischemic Conditioning) in Older Individuals

for Old Age

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 65+

Code: NCT06476288·Enrolling By Invitation

Long-term Safety and Efficacy Evaluation of Lunsekimig (SAR443765) in Adult Participants With Asthma

for Asthma

Drug: Lunsekimig

27 locations incl. Chandler

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06609239·Phase 2·Enrolling By Invitation

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

221 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06317649·Phase 2·Recruiting

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Registry for Stage 2 Type 1 Diabetes

for Type 1 Diabetes

37 locations incl. Los Angeles

Sponsor: Sanofi

Sex: All·Age: All ages

Code: NCT06481904·Recruiting

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A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

for Breast Cancer

165 locations incl. Daphne

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06492616·Phase 3·Recruiting

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A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver Disease

for Liver Diseases, Alcoholic

27 locations incl. Chandler

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 70

Code: NCT06613698·Phase 2·Recruiting

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A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

for Alzheimer Disease

Drug: KarXT

98 locations incl. Chandler

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 55 - 90

Code: NCT06585787·Phase 3·Recruiting

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Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

211 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554406·Phase 2·Recruiting

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A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH)

for Gram-negative Bacterial Infection

11 locations incl. Orange

Sponsor: Pfizer

Sex: All·Age: Up to 39 Weeks

Code: NCT06462235·Phase 2·Recruiting

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A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

37 locations incl. Mobile

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06525220·Phase 3·Recruiting

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Registry Study to Observe Long-term Safety of Vamorolone (AGAMREE®) in Patients With Duchenne Muscular Dystrophy-SUMMIT

for Duchenne Muscular Dystrophy

25 locations incl. Phoenix

Sponsor: Catalyst Pharmaceuticals, Inc.

Sex: Male·Age: 2+

Code: NCT06564974·Recruiting

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A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy

for Obstructive Cardiomyopathy, Hypertrophic

Drug: Sotagliflozin

33 locations incl. Phoenix

Sponsor: Lexicon Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06481891·Phase 3·Recruiting

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A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body

for Melanoma

Drug: Cemiplimab

11 locations incl. Los Angeles

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06413680·Phase 1, Phase 2·Recruiting

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Gastroparesis Registry 4

for Gastroparesis

6 locations incl. Scottsdale

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18 - 85

Code: NCT05846802·Recruiting

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Topical Treatment for Atopic Dermatitis

for Atopic Dermatitis

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 9+

Code: NCT06244212·Recruiting

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A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

for Geographic Atrophy

45 locations incl. Tucson

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 60+

Code: NCT06635148·Phase 2·Recruiting

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Suprathel® Use During Prolonged Field Care to Promote Healing and Reduce the Need for Grafting of Burn Wounds

for Wound of Skin

1 location in Chapel Hill

Sponsor: The Metis Foundation

Sex: All·Age: 18 - 75

Code: NCT05462860·Recruiting

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A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

68 locations incl. Birmingham

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting

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A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

for B-cell Malignancies

10 locations incl. La Jolla

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06542250·Phase 1, Phase 2·Recruiting

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An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

for Colitis, Ulcerative

22 locations incl. Mesa

Sponsor: Pfizer

Sex: All·Age: 18 - 64

Code: NCT06398626·Recruiting

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A Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor Neuropathy

for Multifocal Motor Neuropathy

10 locations incl. Scottsdale

Sponsor: Dianthus Therapeutics

Sex: All·Age: 18 - 75

Code: NCT06537999·Phase 2·Recruiting

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Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

for Non Small Cell Lung Cancer

Drug: Osimertinib

146 locations incl. Birmingham

Sponsor: PrECOG, LLC.

Sex: All·Age: 18+

Code: NCT06538038·Recruiting

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A Study of Obexelimab in Patients With Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

16 locations incl. Fresno

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 70

Code: NCT06559163·Phase 2·Recruiting

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LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

for Metabolic Dysfunction Associated Steatohepatitis (MASH)

Drug: Survodutide

165 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06632444·Phase 3·Recruiting

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Single Versus Dual Implant Fixation of Distal Femur Fractures

for Articular Fractures

16 locations incl. Birmingham

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06286670·Recruiting

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REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women

for Coronary Artery Disease

18 locations incl. Glendale

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18+

Code: NCT06399692·Phase 3·Recruiting

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Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

167 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554393·Phase 2·Recruiting

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Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial

for Prostate Adenocarcinoma

5 locations incl. Los Angeles

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT06022822·Phase 2·Recruiting

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Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

for Liver Transplant

8 locations incl. Phoenix

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06280950·Phase 2·Recruiting

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MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

for Pancreatic Ductal Adenocarcinoma

25 locations incl. Duarte

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06586515·Phase 1·Recruiting

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Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction

for Heart Failure With Preserved Ejection Fraction

8 locations incl. Naples

Sponsor: Medtronic Cardiac Rhythm and Heart Failure

Sex: All·Age: 18+

Code: NCT05839730·Recruiting

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Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for Metastatic Dedifferentiated Liposarcoma

245 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06422806·Phase 3·Recruiting

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A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

for Non-cystic Fibrosis Bronchiectasis

29 locations incl. Birmingham

Sponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA

Sex: All·Age: 18 - 80

Code: NCT06559150·Phase 2·Recruiting

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A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

for Lung Diseases, Interstitial

16 locations incl. Los Angeles

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06572384·Phase 3·Recruiting

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Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

for Migraine

Drug: Ubrogepant

103 locations incl. Birmingham

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06417775·Phase 3·Recruiting

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A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for Melanoma

104 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06246916·Phase 3·Recruiting

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RevCore for In Stent Thrombosis

for In-stent Thrombosis

16 locations incl. New Haven

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT06394739·Recruiting

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Evaluation of Ascorbate-Meglumine Therapeutic for SRS

for Safety

1 location in Durham

Sponsor: LadeRx LLC

Sex: All·Age: 18+

Code: NCT06433791·Phase 1·Enrolling By Invitation

Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent System

for Chronic Heart Failure

2 locations incl. Rochester

Sponsor: AquaPass Medical Ltd.

Sex: All·Age: 21 - 80

Code: NCT06360380·Recruiting

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Post-Operative Cesarean Section Cosmesis

for Cesarean Delivery

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18 - 44·Accepts healthy volunteers

Code: NCT06412978·Recruiting

Apply to this trial