A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumorsfor Advanced Solid Tumors7 locations incl. Los AngelesSponsor: LigaChem Biosciences, Inc.Sex: All·Age: 18+Code: NCT05941507·Phase 1, Phase 2·RecruitingApply to this trial
IKS014 in Advanced Solid Tumors That Express HER2for Breast Cancer4 locations incl. Newport BeachSponsor: Iksuda Therapeutics Ltd.Sex: All·Age: 18+Code: NCT05872295·Phase 1·RecruitingApply to this trial
Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancerfor Breast Cancer8 locations incl. ColumbiaSponsor: SCRI Development Innovations, LLCSex: All·Age: 18+Code: NCT05748834·Phase 2·RecruitingApply to this trial
A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myelomafor Multiple MyelomaDrug: Iberdomide44 locations incl. AuroraSponsor: Bristol-Myers SquibbSex: All·Age: 18+Code: NCT05827016·Phase 3·RecruitingApply to this trial
A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignanciesfor Relapsed/Refractory B-cell Malignancies9 locations incl. DenverSponsor: Accutar Biotechnology IncSex: All·Age: 18+Code: NCT05780034·Phase 1·RecruitingApply to this trial
A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myelomafor Multiple Myeloma13 locations incl. San FranciscoSponsor: K36 Therapeutics, Inc.Sex: All·Age: 18+Code: NCT05651932·Phase 1·RecruitingApply to this trial
CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myelomafor Relapsed/Refractory Multiple Myeloma16 locations incl. BirminghamSponsor: Caribou Biosciences, Inc.Sex: All·Age: 18+Code: NCT05722418·Phase 1·RecruitingApply to this trial
FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3for Urinary Bladder Neoplasms41 locations incl. TucsonSponsor: Eli Lilly and CompanySex: All·Age: 18+Code: NCT05614739·Phase 1·RecruitingApply to this trial
Safety Extension Study for Subjects With HR+, HER2- Breast Cancer for Subjects Who Have Completed the OVELIA Studyfor Breast Cancer17 locations incl. GreenbraeSponsor: Tolmar Inc.Sex: All·Age: 18 - 51Code: NCT05645536·Phase 3·Enrolling By Invitation
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)for High Grade Epithelial Ovarian Cancer37 locations incl. PhoenixSponsor: GenmabSex: All·Age: 18+Code: NCT05579366·Phase 1, Phase 2·RecruitingApply to this trial
Study of INCB123667 in Subjects With Advanced Solid Tumorsfor Solid TumorsDrug: INCB12366719 locations incl. DuarteSponsor: Incyte CorporationSex: All·Age: 18+Code: NCT05238922·Phase 1·RecruitingApply to this trial
A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumorsfor HER2-positive Advanced Solid TumorDrug: DB-1303/BNT32335 locations incl. CerritosSponsor: DualityBio Inc.Sex: All·Age: 18+Code: NCT05150691·Phase 1, Phase 2·RecruitingApply to this trial
First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancerfor PIK3CA Mutation24 locations incl. TucsonSponsor: Relay Therapeutics, Inc.Sex: All·Age: 18+Code: NCT05216432·Phase 1·RecruitingApply to this trial
A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignanciesfor Chronic Lymphocytic Leukemia (CLL)16 locations incl. DuarteSponsor: Nurix Therapeutics, Inc.Sex: All·Age: 18+Code: NCT04830137·Phase 1·RecruitingApply to this trial
A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myelomafor Hematological MalignanciesDrug: Talquetamab14 locations incl. BirminghamSponsor: Janssen Research & Development, LLCSex: All·Age: 18+Code: NCT04634552·Phase 2·RecruitingApply to this trial
Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant Tumorsfor Advanced Solid Tumor15 locations incl. Los AngelesSponsor: Daiichi SankyoSex: All·Age: 18+Code: NCT04145622·Phase 1, Phase 2·RecruitingApply to this trial