Paid Clinical Trials in Missouri

Missouri has 2,061 paid clinical trials enrolling now across cities including St Louis, Kansas City and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Missouri include Washington University School of Medicine, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

2,061 clinical trials

↓ Download CSV

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

16 locations incl. Fountain Valley

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT05932862·Phase 1·Recruiting

Apply to this trial

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

for Solid Tumor, Adult

12 locations incl. Gilbert

Sponsor: A2 Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT06051695·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

for Non Small Cell Lung Cancer

49 locations incl. Little Rock

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06312137·Phase 3·Recruiting

Apply to this trial

A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

for Pulmonary Fibrosis

59 locations incl. Birmingham

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06329401·Phase 2·Recruiting

Apply to this trial

Local Anesthesia for Facial Fractures

for Pain Management

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06429501·Phase 2·Recruiting

Apply to this trial

A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection

for Cystic Fibrosis Lung

13 locations incl. Tucson

Sponsor: Respirion Pharmaceuticals Pty Ltd

Sex: All·Age: 12+

Code: NCT06016088·Phase 1, Phase 2·Recruiting

Apply to this trial

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

for HIV-1-infection

10 locations incl. San Diego

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06071767·Phase 1, Phase 2·Recruiting

Apply to this trial

A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation

for Heart Failure

Drug: Ziltivekimab

41 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT06200207·Phase 3·Recruiting

Apply to this trial

Copper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate Cancer

for Prostate Cancer

44 locations incl. Homewood

Sponsor: Curium US LLC

Sex: Male·Age: 18+

Code: NCT06235151·Phase 3·Recruiting

Apply to this trial

Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery

for Postoperative Pain

5 locations incl. Indianapolis

Sponsor: Pacira Pharmaceuticals, Inc

Sex: All·Age: 0 - 6

Code: NCT06271265·Phase 1·Recruiting

Apply to this trial

Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)

for Immunoglobulin A Nephropathy

46 locations incl. Alabaster

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06291376·Phase 3·Recruiting

Apply to this trial

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

for Recurrent Langerhans Cell Histiocytosis

104 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 180 Days - 22

Code: NCT05828069·Phase 2·Recruiting

Apply to this trial

A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)

for Multiple Sclerosis

17 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18 - 60

Code: NCT06220201·Phase 1·Recruiting

Apply to this trial

Promoting Shared Decision Making for Severe Aortic Stenosis

for Aortic Stenosis

8 locations incl. San Francisco

Sponsor: Massachusetts General Hospital

Sex: All·Age: 65 - 85

Code: NCT06171737·Enrolling By Invitation

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

for Adipocytic Neoplasm

Drug: Selinexor

7 locations incl. Atlanta

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 30

Code: NCT06239272·Phase 1, Phase 2·Recruiting

Apply to this trial

The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System

for Polycystic Ovary Syndrome

24 locations incl. Encino

Sponsor: May Health

Sex: Female·Age: 18 - 40

Code: NCT06206746·Recruiting

Apply to this trial

A Phase 1/1b Study of IAM1363 in HER2 Cancers

for HER2 Mutation-Related Tumors

29 locations incl. La Jolla

Sponsor: Iambic Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT06253871·Phase 1·Recruiting

Apply to this trial

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for Non-small Cell Lung Cancer

18 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06218914·Phase 1·Recruiting

Apply to this trial

Absorbable vs Non-Absorbable Sutures for Hip Capsular Closure

for Labrum Injury of the Hip Joint

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+

Code: NCT06845735·Recruiting

Apply to this trial

A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial

for Recurrent Glioblastoma

Drug: Atezolizumab

4 locations incl. San Francisco

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06069726·Phase 2·Recruiting

Apply to this trial

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

for Neoplasms, Head and Neck

Drug: Dostarlimab

36 locations incl. Jonesboro

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06256588·Phase 3·Recruiting

Apply to this trial

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

41 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06297226·Phase 2·Recruiting

Apply to this trial

Observational PIC Destination Cohort

for HIV-1-infection

4 locations incl. San Francisco

Sponsor: Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

Sex: All·Age: 18+

Code: NCT05985642·Recruiting

Apply to this trial

Strategy for Improving Stroke Treatment Response

for Ischemic Stroke

52 locations incl. Birmingham

Sponsor: Translational Sciences, Inc.

Sex: All·Age: 18+

Code: NCT05948566·Phase 2·Recruiting

Apply to this trial

A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

for Low Grade Serous Ovarian Cancer

Drug: Avutometinib

38 locations incl. Phoenix

Sponsor: Verastem, Inc.

Sex: Female·Age: 18+

Code: NCT06072781·Phase 3·Recruiting

Apply to this trial

ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation

for Aortic Valve Stenosis

67 locations incl. Birmingham

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT05932615·Enrolling By Invitation

A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

for Focal Epilepsy

61 locations incl. Phoenix

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06132893·Phase 2, Phase 3·Recruiting

Apply to this trial

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

141 locations incl. Birmingham

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 80

Code: NCT06318169·Phase 3·Recruiting

Apply to this trial

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

for Oligometastatic Prostate Cancer (OMPC)

41 locations incl. Fayetteville

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT05939414·Phase 3·Recruiting

Apply to this trial

Study of AZD0754 in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

13 locations incl. Duarte

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 130

Code: NCT06267729·Phase 1, Phase 2·Recruiting

Apply to this trial

DORA and LP in Alzheimer's Disease Biomarkers

for Alzheimer Disease

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06274528·Phase 2·Recruiting

Apply to this trial

OLE Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome

for Hyperphagia in Prader-Willi Syndrome

19 locations incl. Birmingham

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 5 - 30

Code: NCT06420297·Phase 3·Enrolling By Invitation

Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

for Stage III Ovarian Cancer

Drug: Niraparib

59 locations incl. Duarte

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT05659381·Phase 3·Recruiting

Apply to this trial

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for Diabetes Mellitus, Type 2

124 locations incl. Chandler

Sponsor: Cleerly, Inc.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT06112418·Recruiting

Apply to this trial

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

29 locations incl. Los Angeles

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06233461·Phase 2·Recruiting

Apply to this trial

Hydrogen's Feasibility and Safety as a Therapy in ECPR

for Cardiac Arrest

4 locations incl. Washington D.C.

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT05574296·Phase 1·Recruiting

Apply to this trial

Sleep as a Mechanism of Change in Alcohol Use

for Insomnia

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 49·Accepts healthy volunteers

Code: NCT06286774·Recruiting

Apply to this trial

IMProving DRug Dosing and Outcomes for Single VEntricle Patients With Fontan Associated Liver Disease

for Fontan Circulation

1 location in Kansas City

Sponsor: Children's Mercy Hospital Kansas City

Sex: All·Age: 8+

Code: NCT06324396·Phase 1·Recruiting

Apply to this trial

Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control

for Periodontitis

1 location in Jefferson City

Sponsor: Missouri Department of Health and Senior Services

Sex: All·Age: 60 - 100·Accepts healthy volunteers

Code: NCT06890676·Recruiting

Apply to this trial

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

for Breast Cancer

673 locations incl. Anchorage

Sponsor: NRG Oncology

Sex: All·Age: 18 - 100

Code: NCT05896189·Recruiting

Apply to this trial