Paid Clinical Trials in Minnesota

Minnesota has 2,375 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,375 clinical trials

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Autologous Induced Pluripotent Stem Cells of Cardiac Lineage for Congenital Heart Disease

for Univentricular Heart

1 location in Rochester

Sponsor: HeartWorks, Inc.

Sex: All·Age: 18 - 40

Code: NCT05647213·Phase 1·Recruiting

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Pilot/Pivotal Study of DBS+Rehab After Stroke

for Stroke

10 locations incl. Phoenix

Sponsor: Enspire DBS Therapy, Inc.

Sex: All·Age: 21+

Code: NCT05701280·Recruiting

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Evaluation of A Clinical Diagnostic Test for CRDS

for Calcium Release Deficiency Syndrome (CRDS)

3 locations incl. San Francisco

Sponsor: Population Health Research Institute

Sex: All·Age: All ages

Code: NCT06188689·Recruiting

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Augmenting Ankle Plantarflexor Function in Cerebral Palsy

for Cerebral Palsy

1 location in Minneapolis

Sponsor: Northern Arizona University

Sex: All·Age: 8 - 21

Code: NCT05154253·Phase 1·Recruiting

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Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for Metastatic Renal Cell Carcinoma

313 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05327686·Phase 2·Recruiting

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Evaluation of Gender-Affirming Treatments on Pulmonary Function in Transgender and Gender Diverse Patients

for Hormonal Gender-Affirming Therapy

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 14+

Code: NCT05587751·Recruiting

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Non-Invasive and Non-Contact Intracranial Pressure Waveform Recording Using Dynamic Video Ophthalmoscopy

for Intracranial Pressure Increase

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 4+·Accepts healthy volunteers

Code: NCT04046523·Recruiting

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mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

for Advanced Esophageal Adenocarcinoma

Drug: Nivolumab

785 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05677490·Phase 3·Recruiting

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Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

for Arrhythmogenic Right Ventricular Cardiomyopathy

8 locations incl. San Francisco

Sponsor: Tenaya Therapeutics

Sex: All·Age: 14 - 65

Code: NCT06311708·Recruiting

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Adipose-derived MSC to Treat Rejection in Kidney Transplant Recipients

for Kidney Transplant

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 70

Code: NCT05456243·Phase 1·Recruiting

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MYLUNG Consortium Part 3: Observational Study

for Carcinoma, Non-Small-Cell Lung

17 locations incl. Daphne

Sponsor: US Oncology Research

Sex: All·Age: 18+

Code: NCT05885698·Recruiting

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A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

for Overactive Bladder

22 locations incl. Homewood

Sponsor: Valencia Technologies Corporation

Sex: All·Age: 18+

Code: NCT05685433·Recruiting

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Pre-transplant Health Coaching to Improve Patient-Reported Outcomes in Lung Transplant Candidates

for Lung Transplant

3 locations incl. Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05426200·Recruiting

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BEETroot Juice to Reverse Functional Impairment in PAD

for Peripheral Artery Disease

4 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 50+

Code: NCT05624125·Recruiting

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Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent Glioblastoma

for High Grade Astrocytic Tumor

Drug: Efineptakin alfa

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05465954·Phase 2·Recruiting

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A Study to See Iftolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old withAutosomal Recessive Polycystic Kidney Disease (ARPKD)

for Autosomal Recessive Polycystic Kidney (ARPKD)

12 locations incl. Washington D.C.

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 28 Days - 18

Code: NCT04782258·Phase 3·Recruiting

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ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

for H3 K27M

67 locations incl. Phoenix

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: All ages

Code: NCT05580562·Phase 3·Recruiting

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Automating Delirium Severity in the ICU

for Intensive Care Unit Delirium

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 50+

Code: NCT06172491·Recruiting

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Ablation With Confirmation of Colorectal Liver Metastases (ACCLAIM)

for Colorectal Liver Metastases

5 locations incl. Miami

Sponsor: Society of Interventional Oncology

Sex: All·Age: 18+

Code: NCT05265169·Recruiting

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Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR

for Aortic Valve Stenosis

6 locations incl. San Francisco

Sponsor: Institut universitaire de cardiologie et de pneumologie de Québec, University Laval

Sex: All·Age: 18+

Code: NCT05459233·Recruiting

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Alleviant ALLAY-HF Study

for Heart Failure

53 locations incl. Birmingham

Sponsor: Alleviant Medical, Inc.

Sex: All·Age: 40+

Code: NCT05685303·Enrolling By Invitation

Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial

for Abdominal Aortic Aneurysm

32 locations incl. Loma Linda

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 20+

Code: NCT05378347·Recruiting

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Acalabrutinib, Venetoclax and Durvalumab for the Treatment of Richter Transformation From Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

Drug: Durvalumab

3 locations incl. Palo Alto

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05388006·Phase 2·Recruiting

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The Actuate-CBC Study

for Telemedicine

4 locations incl. Orange

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05917652·Recruiting

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MAGNETIC RESONANCE SPECTROSCOPY BIOMARKERS IN TYPE 3 GAUCHER DISEASE (GD3)

for Gaucher Disease, Type 3

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 80

Code: NCT05586243·Recruiting

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Udall Project 2 Aim 2A&C

for Parkinson Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: All ages

Code: NCT05656586·Recruiting

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Evaluation of Oral Potentially Malignant Disorders (OPMDs) with STRATICYTE™

for Mouth Diseases

5 locations incl. Birmingham

Sponsor: Proteocyte Diagnostics Inc.

Sex: All·Age: 18+

Code: NCT05853783·Recruiting

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JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

for Patellar Dislocation, Recurrent

16 locations incl. Redwood City

Sponsor: Hospital for Special Surgery, New York

Sex: All·Age: 10 - 35

Code: NCT06883396·Recruiting

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Study of ONCOFID-P-B (PACLITAXEL-HYALURONIC ACID)

for Bladder Carcinoma in Situ (CIS)

6 locations incl. Gilbert

Sponsor: Fidia Farmaceutici s.p.a.

Sex: All·Age: 18+

Code: NCT05024773·Phase 3·Recruiting

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Metastatic Leiomyosarcoma Biomarker Protocol

for Leiomyosarcoma

9 locations incl. Santa Monica

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: All ages

Code: NCT05653388·Recruiting

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Dual BET and CBP/p300 Inhibitor in Patients With Targeted Advanced Solid Tumors and Hematological Malignancies

for Castrate Resistant Prostate Cancer

6 locations incl. Phoenix

Sponsor: Epigenetix, Inc.

Sex: All·Age: 18+

Code: NCT05488548·Phase 1·Recruiting

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Impella ECP Study (ECP Study) and Impella ECP Continued Access Protocol

for High-Risk Percutaneous Coronary Intervention

32 locations incl. Phoenix

Sponsor: Abiomed Inc.

Sex: All·Age: 18 - 90

Code: NCT05334784·Enrolling By Invitation

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

for Medulloblastoma

10 locations incl. Palo Alto

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 59 Months

Code: NCT05535166·Phase 2·Recruiting

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Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for Advanced Melanoma

Drug: Tebentafusp

25 locations incl. Phoenix

Sponsor: Immunocore Ltd

Sex: All·Age: 18+

Code: NCT05549297·Phase 3·Recruiting

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The Effects of Glucagon on Hepatic Metabolism in People With Type 2 Diabetes After Caloric Restriction

for Type2diabetes

1 location in Rochester

Sponsor: Adrian Vella

Sex: All·Age: 25 - 65

Code: NCT05499702·Phase 2·Recruiting

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Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

for Hematopoietic Cell Transplant

27 locations incl. Birmingham

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: Up to 18

Code: NCT05550298·Recruiting

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Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

for Viral Lung Infection and Acute Respiratory Failure

68 locations incl. Mobile

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05624450·Phase 3·Recruiting

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Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease

for Primary Mitochondrial Disease

20 locations incl. Orange

Sponsor: Abliva AB

Sex: All·Age: 18+

Code: NCT05650229·Phase 2·Recruiting

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Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for Triple Negative Breast Cancer

184 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT05633654·Phase 3·Recruiting

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Maternal Stress, Milk Composition, and Preterm Neurodevelopment

for Prematurity

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 28 Weeks - 34 Weeks

Code: NCT05537454·Recruiting

Apply to this trial