Clinical Trials at Medical College of Wisconsin

As of June 2026, 269 paid clinical trials are recruiting at Medical College of Wisconsin, located at Medical College of Wisconsin: Todd Wehr Library, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, phone (414) 456-8300 in Milwaukee, Wisconsin. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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269 clinical trials at Medical College of Wisconsin

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A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

for Atopic Dermatitis

21 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 Months - 18

Code: NCT05735483·Phase 3·Enrolling By Invitation

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

for Metastatic Salivary Gland Carcinoma

150 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05408845·Phase 2·Recruiting

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Delirium and Neuropsychological Recovery Among Emergency General Surgery Survivors

for Delirium

6 locations incl. Rockford

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 65+

Code: NCT05373017·Recruiting

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Stand up for Your Health With a Sit-stand Desk

for Pre Diabetes

1 location in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18 - 79

Code: NCT05585190·Recruiting

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Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for Metastatic Renal Cell Carcinoma

313 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05327686·Phase 2·Recruiting

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Mixed Methods Study of Health-Related Social Needs in African American Adults With Chronic Kidney Disease and Type 2 Diabetes Mellitus

for Diabetic Nephropathy Type 2 - Uncontrolled

1 location in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18+

Code: NCT05692388·Recruiting

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A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

for Autoimmune Diseases

12 locations incl. Orange

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06587828·Recruiting

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Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction

for Type 2 Diabetes

1 location in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT05593549·EARLY_Phase 1·Recruiting

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Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

for Endometrial Cancer

68 locations incl. Anchorage

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 18+

Code: NCT05640999·Phase 2·Recruiting

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BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for Clinical Stage III Cutaneous Melanoma AJCC v8

Drug: Cabozantinib

222 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05136196·Phase 2·Recruiting

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Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for Endometrial Carcinoma

403 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05256225·Phase 3·Recruiting

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Every Day Counts: A Lifestyle Program for Women With Metastatic Breast Cancer

for Metastatic Breast Cancer

2 locations incl. Maywood

Sponsor: Medical College of Wisconsin

Sex: Female·Age: 18+

Code: NCT03824145·Recruiting

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A Study to Evaluate the Efficacy, Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Satralizumab in Participants With Anti-N-methyl-D-aspartic Acid Receptor (NMDAR) or Anti-leucine-rich Glioma-inactivated 1 (LGI1) Encephalitis

for NMDAR Autoimmune Encephalitis

20 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 12+

Code: NCT05503264·Phase 3·Recruiting

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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

for Type2Diabetes

36 locations incl. Huntsville

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 40 - 80

Code: NCT05390892·Phase 4·Recruiting

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Striated Esophageal Motor Function Modulation in Health and Disease

for Dysphagia, Esophageal

1 location in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT05708885·Recruiting

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Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease

for Idiopathic Pulmonary Fibrosis

86 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 40+

Code: NCT04905693·Phase 3·Enrolling By Invitation

Asciminib Roll-over Study

for Chronic Myelogenous Leukemia

6 locations incl. Ann Arbor

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 7 - 100

Code: NCT04877522·Phase 4·Recruiting

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Pediatric Dose Optimization for Seizures in Emergency Medical Services

for Seizures

20 locations incl. Tucson

Sponsor: Stanford University

Sex: All·Age: 6 Months - 13

Code: NCT05121324·Phase 3·Recruiting

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Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

for Peripartum Cardiomyopathy, Postpartum

64 locations incl. Birmingham

Sponsor: Dennis M. McNamara, MD, MS

Sex: Female·Age: 18+

Code: NCT05180773·Phase 4·Recruiting

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A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

for Unresectable Melanoma

11 locations incl. Los Angeles

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT05361174·Phase 1, Phase 2·Recruiting

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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

1021 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting

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Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

for Advanced Extrapulmonary Neuroendocrine Carcinoma

Drug: Atezolizumab

249 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05058651·Phase 2, Phase 3·Recruiting

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Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for Mesial Temporal Lobe Epilepsy

35 locations incl. Birmingham

Sponsor: Neurona Therapeutics

Sex: All·Age: 18 - 75

Code: NCT05135091·Phase 3·Recruiting

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Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

for Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)

32 locations incl. Birmingham

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 Day - 17

Code: NCT05267821·Phase 2, Phase 3·Recruiting

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Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

for Myelofibrosis

22 locations incl. Duarte

Sponsor: Disc Medicine, Inc

Sex: All·Age: 18+

Code: NCT05320198·Phase 1, Phase 2·Recruiting

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A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)

for Phenylketonuria (PKU)

12 locations incl. Aurora

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: All ages

Code: NCT05813678·Recruiting

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Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

for Locally Advanced Hepatocellular Carcinoma

Drug: Atezolizumab

16 locations incl. Scottsdale

Sponsor: Academic and Community Cancer Research United

Sex: All·Age: 18+

Code: NCT05168163·Phase 2·Recruiting

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REMASTer: REcurrent Brain Metastases After SRS Trial

for Brain Metastases

9 locations incl. Los Angeles

Sponsor: Monteris Medical

Sex: All·Age: 18+

Code: NCT05124912·Recruiting

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A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

for Chronic Lymphocytic Leukemia (CLL)

18 locations incl. Duarte

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05131022·Phase 1·Recruiting

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Long-Term Follow-up Study

for Lymphoma, Non-Hodgkin

31 locations incl. Birmingham

Sponsor: Caribou Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05332054·Enrolling By Invitation

Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations

for Metastatic Non Small Cell Lung Cancer

36 locations incl. Chandler

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT05215340·Phase 3·Recruiting

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A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

14 locations incl. Palo Alto

Sponsor: Regeneron Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT05125016·Phase 1, Phase 2·Recruiting

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Clinical Utility of Residual Hearing in the Cochlear Implant Ear

for Hearing Loss, Sensorineural

5 locations incl. Rochester

Sponsor: Ohio State University

Sex: All·Age: 18 - 79

Code: NCT04707885·Recruiting

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A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

for Relapsed/Refractory Multiple Myeloma

Drug: Daratumumab

16 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT04973605·Phase 1, Phase 2·Recruiting

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Donor-Derived Ex-Vivo Expanded Natural Killer Cell Infusions in Children and Young Adults With High Risk Acute Myeloid Leukemia Receiving Myeloablative HLA-Haploidentical Hematopoietic Cell Transplant

for Acute Myeloid Leukemia

13 locations incl. Phoenix

Sponsor: Michael Pulsipher

Sex: All·Age: 0 - 25

Code: NCT04836390·Phase 2·Enrolling By Invitation

IT Matters: The Erectile Restoration Registry

for Erectile Dysfunction

21 locations incl. Los Angeles

Sponsor: Boston Scientific Corporation

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT04200937·Enrolling By Invitation

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

for Endometrial Cancer

24 locations incl. Phoenix

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT05051722·Recruiting

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Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

for Pulmonary Embolism

57 locations incl. Long Beach

Sponsor: Penumbra Inc.

Sex: All·Age: 18+

Code: NCT04798261·Recruiting

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

812 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting

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Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

for Metastatic Lung Small Cell Carcinoma

223 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT04804644·Phase 3·Recruiting

Apply to this trial