Blinatumomab Consolidation in Real Worldfor B-Cell Acute Lymphoblastic Leukaemia1 location in MilwaukeeSponsor: Medical College of WisconsinSex: All·Age: 18+·Accepts healthy volunteersCode: NCT07117136·RecruitingApply to this trial
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancerfor Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma279 locations incl. GilbertSponsor: NRG OncologySex: All·Age: 18+Code: NCT06958328·Phase 3·RecruitingApply to this trial
Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavityfor Gastric Adenocarcinoma55 locations incl. IrvineSponsor: ECOG-ACRIN Cancer Research GroupSex: All·Age: 18+Code: NCT07001748·Phase 2, Phase 3·RecruitingApply to this trial
Frontline T-cell Engager vs Autologous Stem Cell Transplant (ASCT) and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myelomafor Multiple Myeloma, Newly Diagnosed11 locations incl. BirminghamSponsor: SCRI Development Innovations, LLCSex: All·Age: 19+Code: NCT06974786·Phase 2·RecruitingApply to this trial
MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomesfor Stroke1 location in MilwaukeeSponsor: Medical College of WisconsinSex: All·Age: 18 - 85Code: NCT06930638·Phase 2·RecruitingApply to this trial
Mechanisms of Improving Fecal Continence Muscles Motor Functionfor Fecal Incontinence1 location in MilwaukeeSponsor: Medical College of WisconsinSex: All·Age: 18+·Accepts healthy volunteersCode: NCT06532123·RecruitingApply to this trial
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3for COPD18 locations incl. BirminghamSponsor: Apreo Health, Inc.Sex: All·Age: 40 - 84Code: NCT06891755·RecruitingApply to this trial
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPCfor Prostate Cancer25 locations incl. Palo AltoSponsor: Novartis PharmaceuticalsSex: Male·Age: 18 - 100Code: NCT06855277·Phase 3·RecruitingApply to this trial
Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancerfor Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8149 locations incl. GilbertSponsor: NRG OncologySex: All·Age: 18+Code: NCT06532279·Phase 2·RecruitingApply to this trial
Symptom Monitoring Using Patient-Report to Improve Medication Usefor Breast Cancer Early Stage Breast Cancer (Stage 1-3)3 locations incl. ChicagoSponsor: Medical College of WisconsinSex: Female·Age: 18+Code: NCT06765707·Enrolling By Invitation
Long-Term Extension Study of Vosoritide to Treat Children With Hypochondroplasiafor HypochondroplasiaDrug: Vosoritide4 locations incl. WilmingtonSponsor: BioMarin PharmaceuticalSex: All·Age: All agesCode: NCT07073014·Phase 3·Enrolling By Invitation
A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitisfor Atopic DermatitisDrug: Ruxolitinib20 locations incl. BirminghamSponsor: Incyte CorporationSex: All·Age: 6 - 17Code: NCT06832618·Phase 3·RecruitingApply to this trial
Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)for Myelodysplastic Syndrome138 locations incl. BerkeleySponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT06577441·Phase 2·RecruitingApply to this trial
High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancerfor Head and Neck Squamous Cell Carcinoma200 locations incl. GilbertSponsor: Alliance for Clinical Trials in OncologySex: All·Age: 18+Code: NCT06992427·Phase 3·RecruitingApply to this trial
A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancerfor Metastatic Castration-resistant Prostate Cancer19 locations incl. PhoenixSponsor: Syncromune, Inc.Sex: Male·Age: 18+Code: NCT06533644·Phase 2·RecruitingApply to this trial
Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancerfor Ovarian Cancer21 locations incl. BirminghamSponsor: Regeneron PharmaceuticalsSex: Female·Age: 18+Code: NCT06787612·Phase 2·RecruitingApply to this trial
A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinibfor Chronic Lymphocytic Leukemia20 locations incl. JacksonvilleSponsor: Eli Lilly and CompanySex: All·Age: 18+Code: NCT06876649·Phase 4·RecruitingApply to this trial
A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphomafor Chronic Lymphocytic Leukemia18 locations incl. MiamiSponsor: Eli Lilly and CompanySex: All·Age: 18+Code: NCT06876662·Phase 4·RecruitingApply to this trial
Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)for Acute Myeloid Leukemia129 locations incl. TucsonSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT06672146·Phase 2·RecruitingApply to this trial
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)for Prostate Cancer50 locations incl. PhoenixSponsor: Merck Sharp & Dohme LLCSex: Male·Age: 18+Code: NCT06925737·Phase 3·RecruitingApply to this trial
Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemiafor Severe Aplastic Anemia25 locations incl. BirminghamSponsor: Medical College of WisconsinSex: All·Age: 3 - 75Code: NCT06517641·Phase 2·RecruitingApply to this trial
Heat, Microvascular Function and Agingfor Aging1 location in MilwaukeeSponsor: William HughesSex: All·Age: 18 - 80·Accepts healthy volunteersCode: NCT06633198·EARLY_Phase 1·RecruitingApply to this trial
Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple Myelomafor Recurrent Multiple Myeloma40 locations incl. AmesSponsor: Alliance for Clinical Trials in OncologySex: All·Age: 18+Code: NCT06232044·Phase 1, Phase 2·RecruitingApply to this trial
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)for Lymphoma, Large B-Cell, DiffuseDrug: Polatuzumab Vedotin70 locations incl. MobileSponsor: Merck Sharp & Dohme LLCSex: All·Age: 18+Code: NCT06890884·Phase 2·RecruitingApply to this trial
Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosisfor Multiple Sclerosis, Relapsing-Remitting12 locations incl. Loma LindaSponsor: Bristol-Myers SquibbSex: All·Age: 10 - 17Code: NCT06408259·Phase 3·RecruitingApply to this trial
A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)for Graft-versus-host Disease (GVHD)Drug: Ruxolitinib30 locations incl. Palo AltoSponsor: Incyte CorporationSex: All·Age: 18+Code: NCT06615050·Phase 3·RecruitingApply to this trial
A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)for Gastrointestinal Stromal Tumor (GIST)32 locations incl. BirminghamSponsor: Kura Oncology, Inc.Sex: All·Age: 18+Code: NCT06655246·Phase 1·RecruitingApply to this trial
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancerfor Carcinoma, Non-Small-Cell LungDrug: LY353798285 locations incl. HuntsvilleSponsor: Eli Lilly and CompanySex: All·Age: 18+Code: NCT06890598·Phase 3·RecruitingApply to this trial
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancerfor Clear Cell Renal Cell Carcinoma414 locations incl. PhoenixSponsor: Alliance for Clinical Trials in OncologySex: All·Age: 18+Code: NCT06661720·Phase 3·RecruitingApply to this trial
A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancerfor Metastatic Castration-resistant Prostate Cancer55 locations incl. BirminghamSponsor: CelgeneSex: Male·Age: 18+Code: NCT06764485·Phase 3·RecruitingApply to this trial
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancerfor Fallopian Tube Endometrioid AdenocarcinomaDrug: Bevacizumab658 locations incl. BirminghamSponsor: NRG OncologySex: All·Age: 18+Code: NCT06580314·Phase 3·RecruitingApply to this trial
A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)for Relapsed or Refractory Multiple Myeloma (RRMM)22 locations incl. BirminghamSponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb CompanySex: All·Age: 18+Code: NCT06615479·Phase 3·RecruitingApply to this trial
A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)for Small Cell Lung CancerDrug: Gocatamig9 locations incl. AuroraSponsor: Merck Sharp & Dohme LLCSex: All·Age: 18+Code: NCT06780137·Phase 1, Phase 2·RecruitingApply to this trial
Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapyfor Prostate Cancer27 locations incl. Los AngelesSponsor: Novartis PharmaceuticalsSex: Male·Age: 18 - 100Code: NCT06780670·Phase 2, Phase 3·RecruitingApply to this trial
A Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirusfor Congenital Cytomegalovirus Infection10 locations incl. BirminghamSponsor: National Institute of Allergy and Infectious Diseases (NIAID)Sex: All·Age: 0 Days - 90 DaysCode: NCT06118515·Phase 1·RecruitingApply to this trial
Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trialfor Castration-Resistant Prostate Carcinoma107 locations incl. BirminghamSponsor: Alliance for Clinical Trials in OncologySex: All·Age: 18+Code: NCT06632977·Phase 2·RecruitingApply to this trial
Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapyfor Anaplastic Large Cell Lymphoma, ALK-Negative158 locations incl. BirminghamSponsor: Eastern Cooperative Oncology GroupSex: All·Age: 18 - 75Code: NCT06724237·Phase 3·RecruitingApply to this trial
A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligofor NonSegmental VitiligoDrug: Ruxolitinib80 locations incl. BirminghamSponsor: Incyte CorporationSex: All·Age: 2 - 11Code: NCT06548360·Phase 3·RecruitingApply to this trial
Autonomic Reactivity and Personalized Neurostimulationfor Functional Gastrointestinal Disorders (FGIDs)1 location in MilwaukeeSponsor: Medical College of WisconsinSex: Female·Age: 11 - 18·Accepts healthy volunteersCode: NCT06863207·RecruitingApply to this trial
DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)for Pulmonary Hypertension Due to Lung Diseases and Hypoxia66 locations incl. BirminghamSponsor: United TherapeuticsSex: All·Age: 18+Code: NCT06388421·RecruitingApply to this trial