Breast cancer Clinical Trials in Los Angeles, CA

As of June 2026, 66 paid clinical trials are recruiting for Breast cancer in Los Angeles, California. Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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Oncology· 851 Women's health· 140 Breast oncology· 102

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66 clinical trials for Breast cancer

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Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

for Breast Cancer

79 locations incl. Phoenix

Sponsor: BriaCell Therapeutics Corporation

Sex: All·Age: 18+

Code: NCT06072612·Phase 3·Recruiting

Apply to this trial

Reinvigorating TNBC Response to Immunotherapy With Combination Myeloid Inhibition and Radiation

for TNBC - Triple-Negative Breast Cancer

1 location in Los Angeles

Sponsor: Stephen Shiao

Sex: Female·Age: 18+

Code: NCT05491226·Phase 2·Recruiting

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OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

for Breast Cancer

Drug: Palazestrant

47 locations incl. Tucson

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06016738·Phase 3·Recruiting

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[177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer

for Breast Cancer

Drug: Ribociclib

6 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT05870579·Phase 1·Recruiting

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Access to Genetic Testing in Underserved Patients With Cancer

for Breast Carcinoma

2 locations incl. Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06422455·Recruiting

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

1208 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting

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Utilizing Advocates and Supporters to Increase Lung Cancer Screening Rates in Eligible Participants

for Breast Carcinoma

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 40 - 80·Accepts healthy volunteers

Code: NCT05978128·Recruiting

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First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

for Breast Cancer

28 locations incl. Los Angeles

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05768139·Phase 1, Phase 2·Recruiting

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(Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer

for Breast Neoplasms

15 locations incl. Phoenix

Sponsor: Atossa Therapeutics, Inc.

Sex: Female·Age: 18+

Code: NCT05607004·Phase 2·Recruiting

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Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer

for Breast Cancer

45 locations incl. Dothan

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05563220·Phase 1, Phase 2·Recruiting

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Randomized Feasibility Trial for Mesh in Pre-Pectoral Reconstruction

for Breast Cancer

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: Female·Age: 22 - 75

Code: NCT05190978·Recruiting

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Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

for Breast Neoplasms

11 locations incl. Fullerton

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05386108·Phase 1, Phase 2·Recruiting

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Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

for Breast Cancer

51 locations incl. Mobile

Sponsor: Greenwich LifeSciences, Inc.

Sex: All·Age: 18 - 100

Code: NCT05232916·Phase 3·Recruiting

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Faith in Action! A Church-Based Navigation Model to Increase Breast Cancer Screening in Korean Women

for Breast Cancer Female

2 locations incl. Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: Female·Age: 45 - 80·Accepts healthy volunteers

Code: NCT05298605·Recruiting

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Breast Cancer Survivorship Biorepository

for Anatomic Stage I Breast Cancer AJCC v8

1 location in Los Angeles

Sponsor: University of Southern California

Sex: Female·Age: 18+

Code: NCT05786664·Recruiting

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FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer

for Breast Cancer

8 locations incl. La Jolla

Sponsor: Regor Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT05304962·Phase 1·Recruiting

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A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study

for Ovarian Neoplasms

Drug: Niraparib

13 locations incl. Tucson

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT04641247·Phase 2·Recruiting

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DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)

for Breast Cancer

19 locations incl. Tucson

Sponsor: Criterium, Inc.

Sex: All·Age: All ages

Code: NCT04567420·Phase 2·Recruiting

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Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses

for Breast Carcinoma

2 locations incl. Los Angeles

Sponsor: University of Southern California

Sex: Female·Age: 18+

Code: NCT06171607·Phase 1·Recruiting

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for Advanced Solid Tumor

32 locations incl. Irvine

Sponsor: PMV Pharmaceuticals, Inc

Sex: All·Age: 12+

Code: NCT04585750·Phase 1, Phase 2·Recruiting

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A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

for Advanced Malignant Neoplasm

4 locations incl. Los Angeles

Sponsor: AtlasMedx, Incorporated

Sex: All·Age: 18+

Code: NCT04503265·Phase 1, Phase 2·Recruiting

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Converting HR+ Breast Cancer Into an Individualized Vaccine

for Breast Cancer

8 locations incl. Los Angeles

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18 - 90

Code: NCT03804944·Phase 2·Recruiting

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Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

for Breast Cancer

451 locations incl. Fairbanks

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 35+

Code: NCT03488693·Phase 3·Recruiting

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Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

for Breast Cancer Screening

11 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: Female·Age: 30 - 74·Accepts healthy volunteers

Code: NCT02620852·Recruiting

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Core Biopsies for Establishing a Breast Tumor Tissue Repository

for Breast Cancer

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT02250352·Recruiting

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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

42 locations incl. Birmingham

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting

Apply to this trial