Paid Clinical Trials in Kentucky

Kentucky has 1,050 paid clinical trials enrolling now across cities including Louisville, Lexington and Edgewood. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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1,050 clinical trials

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A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

14 locations incl. Palo Alto

Sponsor: Regeneron Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT05125016·Phase 1, Phase 2·Recruiting

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The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid Tumors

for Non-Small-Cell Lung Carcinoma

1 location in Elizabethtown

Sponsor: VastBiome

Sex: All·Age: 18+

Code: NCT05037825·Recruiting

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First in Human Study of TORL-1-23 in Participants With Advanced Cancer

for Advanced Solid Tumor

9 locations incl. Fullerton

Sponsor: TORL Biotherapeutics, LLC

Sex: All·Age: 18+

Code: NCT05103683·Phase 1·Recruiting

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Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

for Renal Pelvis and Ureter Urothelial Carcinoma

Drug: Durvalumab

258 locations incl. Kingman

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04628767·Phase 2, Phase 3·Recruiting

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Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

for Breast Cancer, NOS

347 locations incl. Fairbanks

Sponsor: Eastern Cooperative Oncology Group

Sex: All·Age: 18 - 39

Code: NCT05108298·Recruiting

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Desara ® One Single Incision Sling 522 Study

for Stress Urinary Incontinence

15 locations incl. Phoenix

Sponsor: Caldera Medical, Inc.

Sex: Female·Age: 18+

Code: NCT04772131·Recruiting

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Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

for Non-Small Cell Lung Cancer

Drug: Bevacizumab

18 locations incl. Duarte

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT05005403·Phase 1·Recruiting

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Time-Restricted Feeding Intervention in Metabolically-Unhealthy Postmenopausal Women

for Metabolic Syndrome

1 location in Lexington

Sponsor: Julie Pendergast

Sex: Female·Age: 45 - 65·Accepts healthy volunteers

Code: NCT04893226·Recruiting

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US National OCS Liver Perfusion (OLP) Registry

for Liver Transplant

22 locations incl. Birmingham

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05940857·Recruiting

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Augmented Renal Clearance in Neurocritical Care

for TBI (Traumatic Brain Injury)

2 locations incl. Lexington

Sponsor: University of Alberta

Sex: All·Age: 18 - 85

Code: NCT07410624·Recruiting

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Intermediate Visual Space Perception

for Vision

1 location in Louisville

Sponsor: University of Louisville

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT05419713·Recruiting

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JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

for AAA

29 locations incl. Huntsville

Sponsor: Endologix

Sex: All·Age: 21+

Code: NCT05064540·Recruiting

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Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome

for Interstitial Cystitis

1 location in Louisville

Sponsor: University of Louisville

Sex: Female·Age: 18 - 65·Accepts healthy volunteers

Code: NCT04845217·Phase 1, Phase 2·Recruiting

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Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

843 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting

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A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

for B-cell Malignancy

31 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05006716·Phase 1, Phase 2·Recruiting

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Perform Humeral System Study

for Osteoarthritis Shoulder

6 locations incl. Lexington

Sponsor: Stryker Trauma and Extremities

Sex: All·Age: 18+

Code: NCT05067543·Recruiting

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Blue Protocol and Eko Artificial Intelligence Are Best (BEA-BEST)

for Acute Respiratory Failure

1 location in Louisville

Sponsor: University of Louisville

Sex: All·Age: 18 - 100

Code: NCT05144633·Recruiting

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Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib

for Carcinoma, Non-Small Cell Lung

Drug: Osimertinib

10 locations incl. Los Angeles

Sponsor: Genprex, Inc.

Sex: All·Age: 18+

Code: NCT04486833·Phase 1, Phase 2·Recruiting

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Study of Palliative Radiation Combined with Pembrolizumab in Unresectable Metastatic Stage IV Breast Cancer

for Metastatic Breast Cancer

1 location in Louisville

Sponsor: University of Louisville

Sex: Female·Age: 18+

Code: NCT04990921·Phase 2·Recruiting

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High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

for Metastatic Prostate Cancer

17 locations incl. Aurora

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05011383·Phase 2·Recruiting

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Non-invasive Spinal Stimulation as an Adjuvant Therapy for Trunk Control After Pediatric SCI

for Spinal Cord Injuries

1 location in Louisville

Sponsor: University of Louisville

Sex: All·Age: 3 - 12

Code: NCT05091463·Enrolling By Invitation

Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

for Acute Myocardial Infarction

Drug: Selatogrel

81 locations incl. Alexander City

Sponsor: Viatris Innovation GmbH

Sex: All·Age: 18+

Code: NCT04957719·Phase 3·Enrolling By Invitation

Zimmer Biomet Shoulder Arthroplasty PMCF

for Shoulder Fractures

12 locations incl. Irvine

Sponsor: Zimmer Biomet

Sex: All·Age: 20+

Code: NCT04984291·Recruiting

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A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

29 locations incl. Birmingham

Sponsor: UCB Biopharma SRL

Sex: All·Age: 16+

Code: NCT04976322·Phase 3·Enrolling By Invitation

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

149 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting

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A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine

for Chronic Migraine in Children

22 locations incl. New Haven

Sponsor: H. Lundbeck A/S

Sex: All·Age: 12 - 17

Code: NCT04965675·Phase 3·Recruiting

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Trial of Therapeutic Hypothermia in Patients With ARDS

for Respiratory Distress Syndrome, Adult

19 locations incl. Los Angeles

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 85

Code: NCT04545424·Phase 2·Recruiting

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

812 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting

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APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

for Pancreatic Acinar Cell Carcinoma

Drug: Olaparib

452 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04858334·Phase 2·Recruiting

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Persona Revision Knee System Outcomes

for Arthroplasty Complications

16 locations incl. Fayetteville

Sponsor: Zimmer Biomet

Sex: All·Age: 18+

Code: NCT04821154·Recruiting

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Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

for Metastatic Lung Small Cell Carcinoma

223 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT04804644·Phase 3·Recruiting

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Trial-Ready Cohort-Down Syndrome (TRC-DS)

for Down Syndrome

18 locations incl. Phoenix

Sponsor: University of Southern California

Sex: All·Age: 25 - 55

Code: NCT04165109·Recruiting

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Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC

for Peritoneal Carcinomatosis

2 locations incl. Lexington

Sponsor: Prakash Pandalai

Sex: All·Age: 18+

Code: NCT04779554·Phase 2·Recruiting

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A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

for Acute Leukemia

26 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 2+

Code: NCT04811560·Phase 1, Phase 2·Recruiting

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GORE® ENFORM Biomaterial Product Study

for Hernia, Ventral

9 locations incl. San Diego

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT04718168·Recruiting

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An Internet-based Program to Help Cancer Survivors Manage Pain

for Cancer

149 locations incl. Fort Smith

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT04462302·Recruiting

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A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

for Pulmonary Arterial Hypertension

28 locations incl. Phoenix

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07218029·Phase 3·Recruiting

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Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

for Locally Advanced (Inoperable) or Metastatic Breast Cancer

54 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18 - 99

Code: NCT04862663·Phase 3·Recruiting

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Administration of Allogeneic-MSC in Patients With Non-Ischemic Dilated Cardiomyopathy

for Non-ischemic Dilated Cardiomyopathy

4 locations incl. Stanford

Sponsor: Joshua M Hare

Sex: All·Age: 18 - 80

Code: NCT04476901·Phase 2·Recruiting

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Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

for Metastatic Non Small Cell Lung Cancer

46 locations incl. Gilbert

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT04614103·Phase 2·Recruiting

Apply to this trial