Clinical Trials at Texas Children's Hospital

As of June 2026, 120 paid clinical trials are recruiting at Texas Children's Hospital, located at 6621 FANNIN ST, HOUSTON, TX 77030-2303, phone (832) 824-1000 in Houston, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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120 clinical trials at Texas Children's Hospital

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Danon Disease Natural History Study

for Danon Disease

8 locations incl. Phoenix

Sponsor: Rocket Pharmaceuticals Inc.

Sex: All·Age: 8+

Code: NCT06214507·Recruiting

Apply to this trial

Cord Clamping Among Neonates With Congenital Heart Disease

for Congenital Heart Disease (CHD)

18 locations incl. Birmingham

Sponsor: Carl Backes, MD

Sex: All·Age: 37 Weeks - 42 Weeks

Code: NCT06153459·Recruiting

Apply to this trial

Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

for Spinal Muscular Atrophy

15 locations incl. Phoenix

Sponsor: Alcyone Therapeutics, Inc

Sex: All·Age: 3+

Code: NCT05866419·Recruiting

Apply to this trial

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

for Hematologic Malignancy

Drug: Venetoclax

5 locations incl. Aurora

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 0 - 38

Code: NCT06131801·Recruiting

Apply to this trial

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

for Single Ventricle Heart Disease

37 locations incl. Phoenix

Sponsor: Mezzion Pharma Co. Ltd

Sex: All·Age: 12 - 18

Code: NCT05918211·Phase 3·Recruiting

Apply to this trial

Fetal Repair of Complex Gastroschisis: A Safety and Feasibility Trial

for Gastroschisis

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: Female·Age: 18+

Code: NCT05704257·Recruiting

Apply to this trial

Neurophysiologic Biomarkers in Rett Syndrome

for Rett Syndrome

6 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: Female·Age: 1 - 18·Accepts healthy volunteers

Code: NCT05932589·Recruiting

Apply to this trial

Marfan Syndrome Moderate Exercise Trial II

for Marfan Syndrome

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 10 - 25

Code: NCT05809323·Recruiting

Apply to this trial

STXBP1 and SYNGAP1 Related Disorders Natural History Study

for Genetic Disease

5 locations incl. Palo Alto

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT06555965·Recruiting

Apply to this trial

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)

for Obstructive Sleep Apnea

7 locations incl. Aurora

Sponsor: Oregon Health and Science University

Sex: All·Age: 2 - 17

Code: NCT05508971·Recruiting

Apply to this trial

Trivalent CAR-T Cell in Acute B-Lineage Leukemia (TRICAR-ALL)

for Leukemia, B-Cell

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 12 Months - 25

Code: NCT05010564·Phase 1·Recruiting

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EVD Drainage Data and Intracranial Pressure (ICP) Measurements

for Hydrocephalus

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 1 - 21

Code: NCT05546996·Recruiting

Apply to this trial

A Retrospective Study to Characterize Participants With Propionic Acidemia

for Propionic Acidemia

6 locations incl. Stanford

Sponsor: ModernaTX, Inc.

Sex: All·Age: 2+

Code: NCT05769621·Recruiting

Apply to this trial

Neurodevelopmental Outcomes in Children: Strengthening the Caregiver-Child Story

for Food Insecurity

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05809115·Recruiting

Apply to this trial

Modernizing Perinatal Syphilis Testing

for Syphilis

9 locations incl. Los Angeles

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: Up to 45

Code: NCT06082453·Recruiting

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VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

for Solid Tumor

Drug: Atezolizumab

7 locations incl. Chicago

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 6 Months - 30

Code: NCT04796012·Phase 1, Phase 2·Recruiting

Apply to this trial

Distal Radius Interventions for Fracture Treatment

for Fracture Distal Radius

25 locations incl. Phoenix

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 4 - 10

Code: NCT05131685·Recruiting

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A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition

for Primary Immune Regulatory Disorder

13 locations incl. San Francisco

Sponsor: Joseph Oved

Sex: All·Age: All ages

Code: NCT05787574·Phase 2·Recruiting

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Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

for Medulloblastoma

10 locations incl. Palo Alto

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 59 Months

Code: NCT05535166·Phase 2·Recruiting

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ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

for Adamantinomatous Craniopharyngioma

8 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 - 39

Code: NCT05233397·Phase 2·Recruiting

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EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study

for Heart Failure

15 locations incl. Los Angeles

Sponsor: Berlin Heart, Inc

Sex: All·Age: Up to 21

Code: NCT05610787·Enrolling By Invitation

EBV Specific T-Lymphocytes for Treatment of EBV-Positive Lymphoma

for EBV-Related Hodgkin Lymphoma

2 locations incl. Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: All ages

Code: NCT04664179·Phase 1·Recruiting

Apply to this trial

Systematic Light Exposure in Pediatric Brain Tumor Survivors

for Brain Tumor

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 10 - 18

Code: NCT05340881·Recruiting

Apply to this trial

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

45 locations incl. Phoenix

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting

Apply to this trial

Rett Syndrome Registry

for Rett Syndrome

18 locations incl. Birmingham

Sponsor: International Rett Syndrome Foundation

Sex: All·Age: 0 - 99

Code: NCT05432349·Recruiting

Apply to this trial

Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

for Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)

32 locations incl. Birmingham

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 Day - 17

Code: NCT05267821·Phase 2, Phase 3·Recruiting

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Uterine Transplant for Women With Absolute Uterine Factor Infertility (AUFI)

for Mayer Rokitansky Kuster Hauser Syndrome

1 location in Houston

Sponsor: John Goss

Sex: Female·Age: 20 - 65

Code: NCT05263076·Recruiting

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A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

for Colitis, Ulcerative

36 locations incl. Phoenix

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 2 - 17

Code: NCT05076175·Phase 2, Phase 3·Recruiting

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Open-label Study of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH)

for Secondary Hemophagocytic Lymphohistiocytosis (sHLH)

18 locations incl. Birmingham

Sponsor: Electra Therapeutics Inc.

Sex: All·Age: 6+

Code: NCT05416307·Phase 2, Phase 3·Recruiting

Apply to this trial

The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis

for Autoimmune Encephalitis

Drug: Inebilizumab

35 locations incl. Birmingham

Sponsor: University of Utah

Sex: All·Age: 12+

Code: NCT04372615·Phase 2·Recruiting

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EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease

for COVID-19

50 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 0 - 17

Code: NCT05261139·Phase 3·Recruiting

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A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

for Crohn's Disease (CD)

22 locations incl. Phoenix

Sponsor: Takeda

Sex: All·Age: 2 - 17

Code: NCT04779320·Phase 3·Recruiting

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TReatment for ImmUne Mediated PathopHysiology

for Acute Liver Failure

24 locations incl. Los Angeles

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 1 - 18

Code: NCT04862221·Phase 2·Recruiting

Apply to this trial

HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome

for Angelman Syndrome

6 locations incl. San Diego

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 0 - 50

Code: NCT05127226·Phase 1, Phase 2·Recruiting

Apply to this trial

Improving Continuous Renal Replacement Therapy Outcomes in Neonates and Infants Through Interdisciplinary Collaboration

for Acute Kidney Injury

9 locations incl. Palo Alto

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT05161078·Enrolling By Invitation

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

for Sarcoma

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 1 - 25

Code: NCT04995003·Phase 1·Recruiting

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Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations

for Healthy Children

5 locations incl. Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 6 Months - 8·Accepts healthy volunteers

Code: NCT04639830·Recruiting

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A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study

for Propionic Acidemia

7 locations incl. Los Angeles

Sponsor: ModernaTX, Inc.

Sex: All·Age: 1+

Code: NCT05130437·Phase 1, Phase 2·Recruiting

Apply to this trial

Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy

for Cardiomyopathy

21 locations incl. Little Rock

Sponsor: Tenaya Therapeutics

Sex: All·Age: 0 - 18

Code: NCT05112237·Recruiting

Apply to this trial

Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome

for Alagille Syndrome

18 locations incl. San Diego

Sponsor: Albireo, an Ipsen Company

Sex: All·Age: All ages

Code: NCT05035030·Phase 3·Recruiting

Apply to this trial