Oncology Clinical Trials in Houston, TX

As of June 2026, 983 paid clinical trials are recruiting for Oncology in Houston, Texas. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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983 clinical trials for Oncology

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Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

9 locations incl. Encino

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 99

Code: NCT07590934·Phase 1, Phase 2·Not Yet Recruiting

Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer

for Ovarian Cancer

5 locations incl. Peoria

Sponsor: Nerviano Medical Sciences

Sex: Female·Age: 18+

Code: NCT06930755·Phase 1·Recruiting

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A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

for Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma

9 locations incl. Los Angeles

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07488676·Phase 1, Phase 2·Recruiting

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AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

for Metastatic Castration-resistant Prostate Cancer

24 locations incl. Dothan

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT07611110·Phase 3·Recruiting

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Barriers And Facilitators To Clinical Trial Enrollment: A Qualitative Study Of Pancreatic Cancer Patients

for Pancreatic Cancer

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07591480·Not Yet Recruiting

Food is Medicine in Survivorship: Examining the Feasibility and Impact of a Scalable Food Delivery and Culinary Medicine Program (FoodiiS) Among Pediatric Cancer Survivors and Their Families

for Pediatric Cancer

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07218328·Not Yet Recruiting

Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

for Glioma

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 36 Months+

Code: NCT07076498·Phase 1·Recruiting

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A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

5 locations incl. Rockville

Sponsor: BioNTech SE

Sex: Male·Age: 18+

Code: NCT07365995·Phase 3·Recruiting

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Dual Administration Of Intraperitoneal And Intravenous TROP2-Directed CAR-NK With TGF-Beta Receptor 2 (TGFBR2) Knock Out (KO) Therapy For Colorectal Cancer-Related Peritoneal Carcinomatosis: A Phase 1/2 Trial ("Chip-CRC Trial")

for Colorectal Cancer

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07411599·Phase 1, Phase 2·Recruiting

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A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers

for Lymphoma, Non-Hodgkin's

Drug: LY4584180

21 locations incl. Scottsdale

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07226843·Phase 1·Recruiting

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A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

for Solid Tumors

Drug: INCB161734

68 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07522073·Phase 3·Recruiting

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A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for Myelodysplastic Syndrome

18 locations incl. Orange

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07422480·Phase 3·Recruiting

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Magnetic Sentinel Lymph Node Mapping in Gastric Cancer

for Gastric Adenocarcinoma

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05038098·Phase 1·Not Yet Recruiting

Hyperpolarized Xenon-129 Magnetic Resonance Imaging in Lung Cancer Patients Receiving Radiation Therapy for Investigating Radiation-response and Toxicity

for Lung Cancer

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06909201·Recruiting

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A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC

for Epidermal Growth Factor

6 locations incl. Los Angeles

Sponsor: EpiBiologics

Sex: All·Age: 18+

Code: NCT07462377·Phase 1·Recruiting

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Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung

for Lung Cancer

8 locations incl. Duarte

Sponsor: Vergent Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT07499674·Phase 3·Recruiting

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Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

for Breast Neoplasms

39 locations incl. Birmingham

Sponsor: Natera, Inc.

Sex: All·Age: 18+

Code: NCT07214532·Recruiting

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A Phase 1b Study of HC-7366, an Agonist of ISR With Immunotherapy in Kidney Cancer (SHARK)

for Phase 1b

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07401875·Phase 1·Recruiting

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Trial of Spiritual Care Interventions for Patients With Cancer

for Advanced Cancer

3 locations incl. New York

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18+

Code: NCT07408310·Recruiting

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Study in Advanced Solid Tumor Patients

for Advanced Solid Tumor

5 locations incl. Boston

Sponsor: Callio Therapeutics

Sex: All·Age: 18+

Code: NCT07300943·Phase 1, Phase 2·Recruiting

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A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

for ER+, HER 2- Breast Cancer

10 locations incl. East Brunswick

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18 - 99

Code: NCT07540572·Phase 1, Phase 2·Recruiting

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A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

for Non-small Cell Lung Cancer (NSCLC)

Drug: Durvalumab

38 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361497·Phase 3·Recruiting

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A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

for Non-Small Cell Lung Cancer (NSCLC)

Drug: Pumitamig

40 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361510·Phase 3·Recruiting

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Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

for Urothelial Cancer

Drug: PF-08634404

39 locations incl. Fayetteville

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07421700·Phase 1, Phase 2·Recruiting

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Stem Cells for Erectile Dysfunction Post RALP

for Erectile Dysfunction

1 location in Houston

Sponsor: The Methodist Hospital Research Institute

Sex: Male·Age: 40 - 70

Code: NCT07048314·Phase 1, Phase 2·Not Yet Recruiting

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

for NSCLC Adenocarcinoma

12 locations incl. Orlando

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT07277413·Phase 1·Recruiting

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A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic Non-Small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: Amivantamab

6 locations incl. Irvine

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07227025·Phase 1, Phase 2·Recruiting

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Group-based Comprehensive Lifestyle Program for Women With Metastatic Breast Cancer

for Metastatic Breast Cancer

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 18+

Code: NCT07179809·Not Yet Recruiting

Study of the Kinesin Oral Molecular Degrader BBI-940 in Subjects With Advanced or Metastatic Breast Cancer

for Breast Cancer

8 locations incl. Los Angeles

Sponsor: Boundless Bio, Inc.

Sex: All·Age: 18+

Code: NCT07408089·Phase 1·Recruiting

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Treatment of Immune Checkpoint Inhibitor-related Diarrhea and/ or Colitis With Ustekinumab in Cancer Patients

for Cancer

Drug: Ustekinumab

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06807593·Phase 2·Recruiting

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A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

for Esophageal Squamous Cell Carcinoma

5 locations incl. Austin

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT07503808·Phase 1·Recruiting

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A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

for Metastatic Castration-Resistant Prostate Cancer

20 locations incl. Goodyear

Sponsor: Kyntra Bio

Sex: Male·Age: 18+

Code: NCT06842498·Phase 2·Recruiting

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Phase 1 Study of JV-394 Autologous Anti-CD94 CAR T for r/r CD94+ T/NK Cell Neoplasms

for Neoplasms

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07382817·Phase 1·Recruiting

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Safety and Proof-of-Concept Study of RPT1G in Adults With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes

for Acute Myeloid Leukemia

2 locations incl. New York

Sponsor: Remedy Plan, Inc.

Sex: All·Age: 18+

Code: NCT07107126·Phase 1·Recruiting

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Trial of THEO-260 (Administered Via Intraperitoneal Route) in Ovarian Cancer Patients

for Ovarian Cancer

1 location in Houston

Sponsor: Theolytics Limited

Sex: Female·Age: 18+

Code: NCT07211659·Phase 1·Recruiting

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Phase 1b Trial of BMS-986504 in Combination With Olaparib in Patients With MTAP Loss

for Advanced Cancer

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07382544·Phase 1·Recruiting

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Development of a Shared Decision Tool to Facilitate Uptake of the Levonorgestrel-releasing Intrauterine System for the Primary Prevention of Endometrial Cancer

for Levonorgestrel

2 locations incl. Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 18+

Code: NCT07382583·Recruiting

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Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

for Carcinoma, Renal Cell

Drug: PF-08634404

101 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07227415·Phase 1, Phase 2·Recruiting

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A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

29 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07266441·Phase 2·Recruiting

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A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

for Advanced Solid Tumor

6 locations incl. Boston

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT07213830·Phase 1, Phase 2·Recruiting

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Conditions in Oncology (Houston, TX)

Solid tumor· 206 Non-small cell lung cancer (NSCLC)· 129 Breast cancer· 113 Cancer (any)· 90 Acute myeloid leukemia (AML)· 71 Ovarian cancer· 60 Colorectal cancer· 59 Pancreatic cancer· 59 Prostate cancer· 49 Hematologic malignancy· 44 Non-Hodgkin lymphoma· 42 Endometrial cancer· 41 Myelodysplastic syndromes (MDS)· 40 Head and neck cancer· 40 Lung cancer· 35 Melanoma· 33 Metastatic breast cancer· 31 Gastric cancer· 31 Multiple myeloma· 30 Esophageal cancer· 27 Bladder cancer· 25 Liver cancer· 23 Glioblastoma· 21 Triple-negative breast cancer· 20 Leukemia (other)· 20 Biliary tract cancer· 19 Cervical cancer· 19 Kidney cancer· 17 Metastatic prostate cancer· 16 Chronic lymphocytic leukemia (CLL)· 16 Diffuse large B-cell lymphoma (DLBCL)· 15 Glioma· 14 Sarcoma· 12 HER2-negative breast cancer· 11 Chronic myelomonocytic leukemia· 11 Myelofibrosis· 11 Follicular lymphoma· 11 Small lymphocytic lymphoma· 11 Hodgkin lymphoma· 10 Mesothelioma· 10 HER2-positive breast cancer· 9 Acute lymphoblastic leukemia· 9 Mantle cell lymphoma· 9 Metastatic colorectal cancer· 8 Gastroesophageal junction cancer· 8 Fallopian tube cancer· 8 Brain metastases· 7 Myeloproliferative neoplasm· 7 Neuroblastoma· 7 Brain cancer· 6 Marginal zone lymphoma· 6 Skin cancer· 6 Thyroid cancer· 6 Soft tissue sarcoma· 6 Pediatric cancer· 6 Small cell lung cancer· 5 Ewing sarcoma· 5 Rhabdomyosarcoma· 5 Neuroendocrine tumors· 5 Gastrointestinal cancer· 4 Burkitt lymphoma· 4 Colon cancer· 3 Rectal cancer· 3 Gynecologic cancer· 3 Osteosarcoma· 3 Uterine cancer· 2