Autoimmune disease Clinical Trials in Houston, TX

As of June 2026, 65 paid clinical trials are recruiting for Autoimmune disease in Houston, Texas. Autoimmune disease research covers a broad spectrum of immune-modulating therapies — JAK inhibitors, biologics, T-cell modulators, and tolerance-inducing agents — across rheumatologic, dermatologic, neurologic, and GI conditions. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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65 clinical trials for Autoimmune disease

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A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)

for Generalized Myasthenia Gravis

Drug: Telitacicept

20 locations incl. Los Angeles

Sponsor: Vor Biopharma

Sex: All·Age: 18+

Code: NCT06456580·Phase 3·Recruiting

Apply to this trial

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

for Ulcerative Colitis

Drug: Tofacitinib

40 locations incl. Dothan

Sponsor: Takeda

Sex: All·Age: 18 - 65

Code: NCT06095128·Phase 4·Recruiting

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A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE)

for Systemic Lupus Erythematosus

46 locations incl. Anniston

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06411249·Phase 4·Recruiting

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A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

for Crohn's Disease

Drug: Tulisokibart

87 locations incl. Dothan

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 16 - 80

Code: NCT06430801·Phase 3·Recruiting

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A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

for Crohn's Disease

Drug: Ustekinumab

45 locations incl. Dothan

Sponsor: Takeda

Sex: All·Age: 18 - 70

Code: NCT06045754·Phase 4·Recruiting

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An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

for Systemic Lupus Erythematosus

22 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 5 - 17

Code: NCT05835310·Phase 3·Recruiting

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RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

21 locations incl. Orange

Sponsor: Cabaletta Bio

Sex: All·Age: 18 - 65

Code: NCT06121297·Phase 1, Phase 2·Recruiting

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Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

for Ulcerative Colitis

53 locations incl. Sun City

Sponsor: Gilead Sciences

Sex: All·Age: 18 - 75

Code: NCT06029972·Phase 2·Recruiting

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Neuromodulating Cortical Regions Involved in Neurogenic Bladder in MS

for Neurogenic Bladder

1 location in Houston

Sponsor: The Methodist Hospital Research Institute

Sex: Female·Age: 18+

Code: NCT06072703·Recruiting

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A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)

for Systemic Lupus Erythematosus

31 locations incl. Aurora

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT05869955·Phase 1·Recruiting

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A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis

for Atopic Dermatitis

Drug: PF-07275315

52 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT05995964·Phase 2·Recruiting

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Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)

for Knee Pain Chronic

16 locations incl. Parker

Sponsor: Zimmer Biomet

Sex: All·Age: 18+

Code: NCT05787821·Recruiting

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A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

for Hidradenitis Suppurativa

Drug: Upadacitinib

87 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 12+

Code: NCT05889182·Phase 3·Recruiting

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A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

for Ulcerative Colitis

22 locations incl. Mobile

Sponsor: Takeda

Sex: All·Age: 2+

Code: NCT05442567·Phase 3·Recruiting

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G7 Freedom Constrained Vivacit-E Liners

for Osteoarthritis, Hip

10 locations incl. Birmingham

Sponsor: Zimmer Biomet

Sex: All·Age: 18 - 80

Code: NCT05587244·Enrolling By Invitation

Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

for Multiple Sclerosis

12 locations incl. New Haven

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55

Code: NCT05285891·Phase 4·Recruiting

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Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

for Ulcerative Colitis

22 locations incl. Irvine

Sponsor: University of California, San Diego

Sex: All·Age: 18+

Code: NCT05230173·Recruiting

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Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

for Ankylosing Spondylitis

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT04751396·Recruiting

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RA-PRO PRAGMATIC TRIAL

for Rheumatoid Arthritis

48 locations incl. Auburn

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT04692493·Phase 3·Recruiting

Apply to this trial

VNS Prospective Neuromodulation of Immune and Gastrointestinal Systems

for Autoimmune Diseases

4 locations incl. Louisville

Sponsor: University of Louisville

Sex: All·Age: 0 - 60

Code: NCT03953768·Recruiting

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Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

for Generalized Myasthenia Gravis

32 locations incl. Birmingham

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT04202341·Recruiting

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

51 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting

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Improving the Quality of Care for Adults With Inflammatory Bowel Disease

for Crohn's Disease

29 locations incl. Los Angeles

Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All·Age: 18 - 99

Code: NCT02791854·Enrolling By Invitation

Study of the Kono-S Anastomosis Versus the Side-to-side Functional End Anastomosis

for Crohn's Disease

6 locations incl. Boston

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18 - 90

Code: NCT03256240·Recruiting

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

142 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting

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Conditions in Autoimmune disease (Houston, TX)

Crohn's disease· 16 Ulcerative colitis· 13 Lupus (SLE)· 12 Rheumatoid arthritis· 11 Myasthenia gravis· 9 Psoriatic arthritis· 7 Multiple sclerosis· 6 Inflammatory bowel disease (IBD)· 5 Psoriasis· 3 Autoimmune diseases (general)· 3 Atopic dermatitis / eczema· 2 Hidradenitis suppurativa· 2