Oncology Clinical Trials in Germantown, TN
As of June 2026, 29 paid clinical trials are recruiting for Oncology in Germantown, Tennessee. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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29 clinical trials for Oncology
·Clear filters·↓ Download CSVSignatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer
A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC
A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis
Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors
A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
Caris Biorepository Research Protocol
About research studies in Germantown
Germantown has approximately 105 recruiting research studies across a wide range of therapeutic areas. Tennessee is home to Vanderbilt University Medical Center and St. Jude Children's Research Hospital — world leaders in pediatric oncology and personalized medicine.
Top Research Study Locations in Germantown
Researchers run research studies in Germantown, TN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| The West Clinic, PLLC dba West Cancer Center | Breast Cancer, Advanced Malignant Tumors, Cancer of the Prostate | 10 |
| The West Clinic - Wolf River | Muscle Invasive Bladder Urothelial Carcinoma, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 9 |
| West Cancer Center | Breast Cancer, Breast Neoplasms, Cancer | 9 |
| Campbell Clinic | Osteo Arthritis Knee, Pain, Postoperative, Acute Comminuted Articular Fracture of Elbow Joint Surfaces | 7 |
| Charles Retina Institute | Neovascular Age-related Macular Degeneration, Corneal Diseases, DME | 7 |
| The Conrad Pearson Clinic | Non-Muscle Invasive Bladder Neoplasms, Benign Prostatic Hyperplasia (BPH), Radical Prostatectomy | 5 |
| West Cancer Center and Research Institute | Advanced Melanoma, Ovarian Cancer, Ovarian Neoplasms | 4 |
| Methodist Le Bonheur Healthcare | Aortic Stenosis, Aortic Stenosis, Calcific, Aortic Valve Stenosis | 3 |
| Stern Cardiovascular Center | Cardiotoxicity, Heart Failure, Heart Failure With Preserved Ejection Fraction | 3 |
| The Stern Cardiovascular Foundation | Cardiovascular Disease and Lipoprotein(a), Diastolic Heart Failure, Heart Failure | 3 |
| The West Clinic | Biliary Tract Cancer, Hepatocellular Carcinoma, Metastatic Breast Cancer | 3 |
| Charles Retina Institute, P.C | AMD, Diabetic Retinopathy, DR, Gene Therapy | 2 |
| Conrad Pearson Clinic | Benign Prostatic Hyperplasia, NMIBC | 2 |
| Stern Cardiovascular Foundation | Heart Failure, Paroxysmal Atrial Fibrillation | 2 |
| Stern Cardiovascular Foundation, Inc. | Heart Failure, Heart Failure With Reduced Ejection Fraction, Hypertension | 2 |
| A | Ankle Surgery, Foot Surgery | 1 |
| Anthos Investigative | Atrial Fibrillation (AF) | 1 |
| Baptist Memorial Hospital Memphis | Aortic Stenosis, Calcific, Aortic Valve Stenosis | 1 |
| Call for Information | Metastatic Castration-Resistant Prostate Cancer | 1 |
| Conrad Pearson-Memphis | FGFR Gene Alterations, FGFR Gene Amplification, FGFR3 Gene Alteration | 1 |
| Exelixis Clinical | Advanced Solid Tumor | 1 |
| GSK Investigational Site | Neoplasms, Head and Neck | 1 |
| Gastro One | Moderately to Severely Active Crohns Disease | 1 |
| GastroOne | Crohn Disease, Ulcerative Colitis | 1 |
| Germantown, TN Investigative | Acute Heart Failure, Heart Failure | 1 |
Active & Upcoming Studies in Germantown (2026)
Recruiting trials in Germantown grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (46 active studies)
- Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer · Natera, Inc.
- A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021) · Phase 3 · Merck Sharp & Dohme LLC
Cardiovascular (14 active studies)
- CCM OPEN HF Registry · Impulse Dynamics
- Novel On-body Evaluation of Cardiac Health for Oncology · Skribe Medical
Eye & vision (10 active studies)
- CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
- A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO · Phase 2 · EyeBiotech Ltd.
Neurology & pain (3 active studies)
- Reverse Shoulder Arthroplasty vs Rotator Cuff Repair for 60+ · Campbell Clinic
- Extended Oral Tranexamic Acid After Total Knee Arthroplasty · Phase 3 · Campbell Clinic
Diabetes & metabolic (1 active study)
Pediatric (1 active study)
- Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients · Phase 1, Phase 2 · St. Jude Children's Research Hospital
Common conditions studied in Germantown
- Heart Failure (7 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Breast Cancer (5 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Hepatocellular Carcinoma (3 active studies). Recruiting Hepatocellular Carcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Neovascular Age-related Macular Degeneration (3 active studies). Recruiting Neovascular Age-related Macular Degeneration studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Non-Muscle Invasive Bladder Neoplasms (3 active studies). Recruiting Non-Muscle Invasive Bladder Neoplasms studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- AMD (2 active studies). Recruiting AMD studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Germantown
- Merck Sharp & Dohme LLC
- Hoffmann-La Roche
- Campbell Clinic
- AbbVie
- Daiichi Sankyo
Local regulations and guidelines
Clinical trials in Tennessee are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Tennessee research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Germantown. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Germantown
Hipa.ai aggregates every recruiting study in Germantown from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Germantown?
There are approximately 105 recruiting clinical trials in Germantown, Tennessee listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Germantown pay participants?
Most recruiting trials in Germantown compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Germantown?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Germantown?
The most common conditions under active study in Germantown include Heart Failure (7), Breast Cancer (5), Hepatocellular Carcinoma (3), Neovascular Age-related Macular Degeneration (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Germantown?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Germantown on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Germantown?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Germantown?
Recruiting research sites in Germantown include The West Clinic, PLLC dba West Cancer Center, The West Clinic - Wolf River, West Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Germantown right now?
The largest active categories in Germantown are Cancer & tumors (46), Cardiovascular (14), Eye & vision (10). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.