GI oncology Clinical Trials in Dallas, TX

As of June 2026, 69 paid clinical trials are recruiting for GI oncology in Dallas, Texas. GI oncology trials cover colorectal, pancreatic, gastric, esophageal, liver, and biliary cancers — testing chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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69 clinical trials for GI oncology

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CEUS vs. AMRI for HCC Detection in Patients With Indeterminate Liver Nodules

for HCC

2 locations incl. Ann Arbor

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06184152·Recruiting

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Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

for Non-Small Cell Lung Cancer (NSCLC)

Drug: daraxonrasib

21 locations incl. Duarte

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06128551·Phase 1, Phase 2·Recruiting

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Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

for Diffuse Astrocytoma, IDH-Mutant

6 locations incl. Beverly Hills

Sponsor: Neonc Technologies, Inc.

Sex: All·Age: 18+

Code: NCT06047379·Phase 1, Phase 2·Recruiting

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A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer

for Gastric Adenocarcinoma

14 locations incl. Duarte

Sponsor: Toray Industries, Inc

Sex: All·Age: 18+

Code: NCT06038578·Phase 2·Recruiting

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Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer

for Hepatocellular Carcinoma

10 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05775159·Phase 2·Recruiting

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A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors

for Ovarian Cancer

2 locations incl. Dallas

Sponsor: Hefei TG ImmunoPharma Co., Ltd.

Sex: All·Age: 18+

Code: NCT05746897·Phase 1·Recruiting

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A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

for Hepatocellular Carcinoma

21 locations incl. Birmingham

Sponsor: Tvardi Therapeutics, Incorporated

Sex: All·Age: 18+

Code: NCT05440708·Phase 1, Phase 2·Recruiting

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Namodenoson in the Treatment of Advanced Hepatocellular Carcinoma in Patients With Child-Pugh Class B7 Cirrhosis

for Hepatocellular Carcinoma

1 location in Dallas

Sponsor: Can-Fite BioPharma

Sex: All·Age: 18+

Code: NCT05201404·Phase 3·Recruiting

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Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

for Barretts Esophagus With Dysplasia

23 locations incl. Los Angeles

Sponsor: University of Colorado, Denver

Sex: All·Age: 18 - 89

Code: NCT05753748·Recruiting

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BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia

for Advanced Solid Tumor

9 locations incl. New Haven

Sponsor: SillaJen, Inc.

Sex: All·Age: 18+

Code: NCT05768932·Phase 1·Recruiting

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A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

for Carcinoma, Non-Small-Cell Lung

25 locations incl. Birmingham

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT05208762·Phase 1·Recruiting

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A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

for Colorectal Neoplasms

128 locations incl. Glendale

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT05253651·Phase 3·Recruiting

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Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01)

for Colorectal Cancer

6 locations incl. Encinitas

Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All·Age: 18+

Code: NCT05464030·Phase 1·Recruiting

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Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

for Mesothelioma

25 locations incl. Phoenix

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT05245500·Phase 1·Recruiting

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A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

for Gastric Adenocarcinoma

13 locations incl. Orange

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT05365581·Phase 1·Recruiting

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GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC

for Hepatocellular Carcinoma

7 locations incl. Duarte

Sponsor: Eureka Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT04864054·Phase 1, Phase 2·Recruiting

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ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for Bladder Carcinoma

33 locations incl. Birmingham

Sponsor: Guardant Health, Inc.

Sex: All·Age: 18+

Code: NCT05059444·Recruiting

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Chemotherapy + Anakinra in Patients With Pancreatic Adenocarcinoma (PDAC)

for Pancreatic Adenocarcinoma

1 location in Dallas

Sponsor: Baylor Research Institute

Sex: All·Age: 18+

Code: NCT04926467·Phase 2·Recruiting

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Minimally Invasive Molecular Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Adenocarcinoma

for Barrett Esophagus

9 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT03961945·Recruiting

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Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

for Solid Tumor

Drug: Givastomig

11 locations incl. Orange

Sponsor: I-Mab Biopharma US Limited

Sex: All·Age: 18+

Code: NCT04900818·Phase 1·Recruiting

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Ultra-fractionated Radiotherapy for Rectal Cancer

for Rectal Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT04677413·Phase 1·Recruiting

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A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

for Advanced Cancer

40 locations incl. Birmingham

Sponsor: Artios Pharma Ltd

Sex: All·Age: 18+

Code: NCT04657068·Phase 1, Phase 2·Recruiting

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for Advanced Solid Tumor

32 locations incl. Irvine

Sponsor: PMV Pharmaceuticals, Inc

Sex: All·Age: 12+

Code: NCT04585750·Phase 1, Phase 2·Recruiting

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Pancreatic Cancer Early Detection Consortium

for Pancreas Cancer

45 locations incl. Phoenix

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04970056·Recruiting

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Early-Onset Colorectal Cancer Patients Too Young for Screening

for Colorectal Cancer

1 location in Dallas

Sponsor: Methodist Health System

Sex: All·Age: 35+

Code: NCT07559825·Recruiting

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Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal Cancer

for Esophagus Adenocarcinoma

1 location in Dallas

Sponsor: Dallas VA Medical Center

Sex: All·Age: 18+

Code: NCT04018872·Phase 2·Recruiting

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A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

for Advanced/Metastatic Solid Tumors

23 locations incl. La Jolla

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT03526835·Phase 1, Phase 2·Recruiting

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SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for Cancer, Metastatic

67 locations incl. Birmingham

Sponsor: Massive Bio, Inc.

Sex: All·Age: All ages

Code: NCT03452774·Recruiting

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American Hepato-Pancreato-Biliary Association (AHPBA) Pancreatic Irreversible Electroporation (IRE) Registry

for Pancreatic Cancer

11 locations incl. Birmingham

Sponsor: University of Louisville

Sex: All·Age: 18+

Code: NCT02674100·Recruiting

Apply to this trial

Conditions in GI oncology (Dallas, TX)

Colorectal cancer· 22 Pancreatic cancer· 20 Gastric cancer· 19 Esophageal cancer· 14 Liver cancer· 11 Biliary tract cancer· 9 Gastroesophageal junction cancer· 7 Metastatic colorectal cancer· 2 Rectal cancer· 1