Urology Clinical Trials in Chicago, IL

As of June 2026, 64 paid clinical trials are recruiting for Urology in Chicago, Illinois. Urology trials cover prostate, bladder, and kidney cancer therapies, BPH and overactive bladder pharmacotherapy, and surgical innovations for stones, incontinence, and urologic reconstruction. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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64 clinical trials for Urology

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rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance

for Prostate Adenocarcinoma

1 location in Chicago

Sponsor: Northwestern University

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT05852041·EARLY_Phase 1·Recruiting

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Clinical Trial of Approaches to Prostate Cancer Surgery

for Prostate Cancer

9 locations incl. Duarte

Sponsor: Weill Medical College of Cornell University

Sex: Male·Age: 40 - 80

Code: NCT05155501·Recruiting

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A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer

for Advanced Prostate Cancer

5 locations incl. Scottsdale

Sponsor: Genentech, Inc.

Sex: Male·Age: 18+

Code: NCT05800665·Phase 1·Recruiting

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MRI Risk Maps for Prostate Cancer Diagnosis Using Targeted Biopsy

for Prostate Cancer

1 location in Chicago

Sponsor: University of Chicago

Sex: Male·Age: 18+

Code: NCT05710380·Recruiting

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Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for Metastatic Renal Cell Carcinoma

313 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05327686·Phase 2·Recruiting

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A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

for Overactive Bladder

22 locations incl. Homewood

Sponsor: Valencia Technologies Corporation

Sex: All·Age: 18+

Code: NCT05685433·Recruiting

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A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A)

for Urothelial Carcinoma

10 locations incl. Orange

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT05562830·Phase 1, Phase 2·Recruiting

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MRI And GPS Informing Choices for Prostate Cancer Treatment (MAGIC)

for Prostate Cancer

2 locations incl. Chicago

Sponsor: Northwestern University

Sex: Male·Age: 40 - 76

Code: NCT05424783·Recruiting

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Anti-inflammatory Drugs and Serum Prostate-Specific Antigen Test

for Prostate Cancer

3 locations incl. Chicago

Sponsor: Albany Medical College

Sex: Male·Age: 18 - 80

Code: NCT05629494·Phase 4·Recruiting

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Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

for Prostate Cancer

32 locations incl. Birmingham

Sponsor: Janux Therapeutics

Sex: Male·Age: 18 - 100

Code: NCT05519449·Phase 1·Recruiting

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Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer

for Hereditary Leiomyomatosis and Renal Cell Carcinoma

Drug: Atezolizumab

13 locations incl. La Jolla

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT04981509·Phase 2·Recruiting

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A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

for Urothelial Carcinoma

159 locations incl. Gilbert

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT04879329·Phase 2·Recruiting

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International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors

for Kidney Cancer

7 locations incl. Los Angeles

Sponsor: Azienda Ospedaliero-Universitaria Careggi

Sex: All·Age: 18+

Code: NCT05363657·Recruiting

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Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

387 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting

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Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for Biochemically Recurrent Prostate Carcinoma

Drug: Apalutamide

342 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male·Age: 18+

Code: NCT04423211·Phase 3·Recruiting

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Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

for Prostate Carcinoma

8 locations incl. Duarte

Sponsor: University of Washington

Sex: Male·Age: 40+·Accepts healthy volunteers

Code: NCT04472338·Recruiting

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Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial

for Prostate Adenocarcinoma

Drug: Apalutamide

345 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT04134260·Phase 3·Recruiting

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A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

for Advanced Solid Tumor

Drug: Tulmimetostat

17 locations incl. Atlanta

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04104776·Phase 1, Phase 2·Recruiting

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SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for Cancer, Metastatic

67 locations incl. Birmingham

Sponsor: Massive Bio, Inc.

Sex: All·Age: All ages

Code: NCT03452774·Recruiting

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Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder

for Urothelial Carcinoma

12 locations incl. Phoenix

Sponsor: Noah Hahn, M.D.

Sex: All·Age: 18+

Code: NCT03317158·Phase 1, Phase 2·Recruiting

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International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

48 locations incl. Birmingham

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting

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A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study

for Prostate Cancer

50 locations incl. Anchorage

Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male·Age: 18+

Code: NCT02960022·Phase 2·Recruiting

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Measuring Surgical Recovery After Radical Cystectomy

for Bladder Cancer

11 locations incl. San Francisco

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT03193970·Recruiting

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Blue Light Cystoscopy With Cysview® Registry

for Bladder Cancer

23 locations incl. Birmingham

Sponsor: Photocure

Sex: All·Age: 18+

Code: NCT02660645·Recruiting

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Conditions in Urology (Chicago, IL)

Prostate cancer· 35 Bladder cancer· 13 Metastatic prostate cancer· 8 Kidney cancer· 6 Overactive bladder· 4 Urinary incontinence· 3