Trastuzumab-Deruxtecan (T-DXd) Evidence: Trial Results and Peer-Reviewed Publications

Hipa.ai Research · Source: PubMed & ClinicalTrials.gov / AACT · Last updated: May 8, 2026

The clinical evidence base for Trastuzumab-Deruxtecan (T-DXd) comprises 1 peer-reviewed publications across 1 journals, 0 pivotal-trial primary-outcome rows reported to ClinicalTrials.gov, spanning indications including Breast Neoplasms. Most recent publication: TUXEDO-4: phase II study of trastuzumab-deruxtecan in HER2-low breast cancer with new or progressing brain metastases., Future Oncol, 2025.

Top peer-reviewed publications

Curated set of pivotal-trial result papers and recent publications in high-tier journals.

TUXEDO-4: phase II study of trastuzumab-deruxtecan in HER2-low breast cancer with new or progressing brain metastases.
Marhold M, Vaz Batista M, Blancas I, et al. · Future Oncol · 2025
PubMed: PMID 40018758 · NCT06048718 (TUXEDO-4) · Breast Neoplasms

Publications by year

2025–2025: 1 publications.

2025

Publications by indication

Breast Neoplasms (1)

TUXEDO-4: phase II study of trastuzumab-deruxtecan in HER2-low breast cancer with new or progressing brain metastases.
Future Oncol · 2025 · PMID 40018758 · NCT06048718

Publications by journal

Future Oncol1 paper

All Trastuzumab-Deruxtecan (T-DXd) publications (1)

2025 (1 paper)

TUXEDO-4: phase II study of trastuzumab-deruxtecan in HER2-low breast cancer with new or progressing brain metastases.
Marhold M, Vaz Batista M, Blancas I, et al. · Future Oncol · 2025 · Derived
PubMed: PMID 40018758 · NCT06048718 (TUXEDO-4) · Breast Neoplasms

Sources and methodology

Publications: ctgov.study_references (PubMed PMIDs auto-attached by ClinicalTrials.gov to each trial), reference types RESULT, DERIVED, and BACKGROUND.
Per-arm outcome values: ctgov.outcome_measurements joined to ctgov.design_outcomes where outcome_type = 'PRIMARY', restricted to phase PHASE3 and PHASE2/PHASE3.
Publication metadata (title, journal, year, authors): PubMed E-utilities efetch.fcgi
Data freshness: Fri, 08 May 2026 19:23:40 GMT.

This page summarizes published evidence for general reference and does not constitute medical advice. For clinical decisions, consult the linked primary publications and your healthcare provider. Data sourced from PubMed and the ClinicalTrials.gov / AACT database maintained by the Clinical Trials Transformation Initiative (CTTI).