Telisotuzumab Vedotin Clinical Trials (2026): 8 Studies for Non-Small Cell Lung Cancer & Non Small Cell Lung Cancer
Hipa.ai Research · Source: ClinicalTrials.gov / AACT
Synced daily from ClinicalTrials.gov via AACT. Last sync: .
8 Telisotuzumab Vedotin clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 6 indications (including Non-Small Cell Lung Cancer & Non Small Cell Lung Cancer) and 1,424 total planned enrollment. 2 Phase 3 Telisotuzumab Vedotin trials and 4 Phase 2 are listed. 3 Telisotuzumab Vedotin clinical trials are actively recruiting at 53 U.S. sites across 23 states. Most recent activity: NCT06093503 (Apr 2028).
Where to Participate: All Telisotuzumab Vedotin Trial Sites in the U.S. (53 sites across 23 states)
Every actively recruiting Telisotuzumab Vedotintrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.
| State | Facility | City | Trial | Map |
|---|---|---|---|---|
| AZ | Ironwood Cancer and Research Center /ID# 276370 | Chandler85224 | NCT06568939 | Map |
| AR | University of Arkansas for Medical Sciences /ID# 272923 | Little Rock72205 | NCT06568939 | Map |
| CA | City of Hope /ID# 243157 | Duarte91010 | NCT04928846 | Map |
| CA | City Of Hope - Seacliff /ID# 263143 | Huntington Beach92648 | NCT04928846 | Map |
| CA | City of Hope - Orange County Lennar Foundation Cancer Center /ID# 263144 | Irvine92618 | NCT04928846 | Map |
| CA | City Of Hope - Antelope Valley /ID# 263138 | Lancaster93534 | NCT04928846 | Map |
| CA | UCLA / Jonsson Comprehensive Cancer Center | Los Angeles90095 | NCT07323641 | Map |
| CA | Valkyrie Clinical Trials /ID# 271322 | Los Angeles90067 | NCT06568939 | Map |
| CA | Eisenhower Medical Center /ID# 233189 | Rancho Mirage92270-3221 | NCT04928846 | Map |
| CA | Premiere Oncology Foundation /ID# 253954 | Santa Monica90404 | NCT04928846 | Map |
| CT | Yale New Haven Hospital /ID# 271584 | New Haven06510 | NCT06568939 | Map |
| FL | Cancer Specialists of North Florida - Jacksonville - AC Skinner Parkway /ID# 270899 | Jacksonville32256 | NCT06568939 | Map |
| FL | Ocala Oncology Center /ID# 273697 | Ocala34474 | NCT06568939 | Map |
| FL | Memorial Hospital West /ID# 270313 | Pembroke Pines33028 | NCT06568939 | Map |
| FL | Comprehensive Hematology Oncology /ID# 270422 | St. Petersburg33701-4732 | NCT06568939 | Map |
| FL | Florida Cancer Specialists - North /ID# 271995 | St. Petersburg33705 | NCT06568939 | Map |
| FL | Florida Cancer Specialists - East /ID# 271993 | West Palm Beach33401 | NCT06568939 | Map |
| GA | University Cancer & Blood Center /ID# 270969 | Athens30607 | NCT06568939 | Map |
| GA | Northwest Georgia Oncology Centers /ID# 275374 | Marietta30060 | NCT06568939 | Map |
| GA | Memorial University Medical Center /ID# 272467 | Savannah31404 | NCT06568939 | Map |
| HI | Kaiser Permanente Moanalua Medical Center /ID# 238363 | Honolulu96819-1469 | NCT04928846 | Map |
| HI | Kaiser Permanente Moanalua Medical Center /ID# 272916 | Honolulu96819 | NCT06568939 | Map |
| IL | University of Illinois Hospital and Health Sciences System /ID# 275345 | Chicago60607 | NCT06568939 | Map |
| IL | Illinois Cancer Specialists /ID# 274678 | Niles60714 | NCT06568939 | Map |
| IL | Springfield Clinic - First /ID# 272576 | Springfield62702 | NCT06568939 | Map |
| MS | Hattiesburg Clinic /ID# 248033 | Hattiesburg39401 | NCT04928846 | Map |
| MO | St. Lukes Hosp. of Kansas City /ID# 259940 | Kansas City64111 | NCT04928846 | Map |
| MO | Hulston Cancer Center /ID# 232226 | Springfield65807-5287 | NCT04928846 | Map |
| NE | NHO - Nebraska Hematology-Oncology /ID# 272970 | Lincoln68506 | NCT06568939 | Map |
| NE | Nebraska Cancer Specialists - Omaha - Wright Street /ID# 271527 | Omaha68130 | NCT06568939 | Map |
| NV | Renown Medical Group - Oncology/Hematology /ID# 247942 | Reno89502-1464 | NCT04928846 | Map |
| NV | Renown Regional Medical Center /ID# 273535 | Reno89502 | NCT06568939 | Map |
| NJ | Astera Cancer Care /ID# 272359 | East Brunswick08816-4096 | NCT06568939 | Map |
| NJ | Regional Cancer Care Associates /ID# 270783 | Teaneck07666 | NCT06568939 | Map |
| NY | Montefiore Medical Center - Einstein Campus /ID# 277169 | The Bronx10461 | NCT06568939 | Map |
| NY | Clinical Research Alliance - Westbury /ID# 270455 | Westbury11590 | NCT06568939 | Map |
| NC | AdventHealth Hendersonville /ID# 265349 | Hendersonville28792 | NCT04928846 | Map |
| NC | FirstHealth of the Carolinas- Speciality Center /ID# 272924 | Pinehurst28374 | NCT06568939 | Map |
| OH | Mercy Health - Perrysburg Cancer Center /ID# 270536 | Perrysburg43551 | NCT06568939 | Map |
| OH | Genesis Healthcare System /ID# 273361 | Zanesville43701 | NCT06568939 | Map |
| PA | Guthrie Robert Packer Hospital /ID# 270316 | Sayre18840 | NCT06568939 | Map |
| PA | Cancer Care Associates Of York /ID# 270971 | York17403 | NCT06568939 | Map |
| SC | Medical University of South Carolina /ID# 251383 | Charleston29425 | NCT04928846 | Map |
| SC | Medical University of South Carolina /ID# 273272 | Charleston29425 | NCT06568939 | Map |
| SC | Saint Francis Cancer Center - Greenville /ID# 276368 | Greenville29607 | NCT06568939 | Map |
| TN | SCRI Oncology Partners /ID# 270162 | Nashville37203 | NCT06568939 | Map |
| TX | Texas Oncology - Dallas - Worth Street /ID# 278947 | Dallas75246 | NCT06568939 | Map |
| TX | Texas Oncology - Northeast Texas /ID# 272000 | Tyler75702 | NCT06568939 | Map |
| UT | Community Cancer Trials Of Utah /ID# 276598 | Ogden84405 | NCT06568939 | Map |
| VA | Virginia Cancer Specialists - Fairfax /ID# 272004 | Fairfax22031 | NCT06568939 | Map |
| WA | Valley Medical Center /ID# 253950 | Renton98055-5738 | NCT04928846 | Map |
| WA | Medical Oncology Associates - Spokane /ID# 277172 | Spokane99208 | NCT06568939 | Map |
| WA | Northwest Medical Specialties Tacoma /ID# 270534 | Tacoma98405 | NCT06568939 | Map |
Telisotuzumab Vedotin clinical trials at a glance: phase × recruitment status
| Phase | recruiting | active not recruiting | terminated | withdrawn | temporarily not available | Total |
|---|---|---|---|---|---|---|
| P1 | 1 | 1 | ||||
| P2 | 2 | 1 | 1 | 4 | ||
| P3 | 1 | 1 | 2 | |||
| N/A | 1 | 1 |
Recruiting Telisotuzumab Vedotin clinical trials (3)
Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).
| NCT ID | Title | Phase | Indication | Enrollment | Started |
|---|---|---|---|---|---|
| NCT04928846 | IVA Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC) | P3 | Non Small Cell Lung Cancer | 698 | Mar 2022 |
| NCT06568939 | IVA Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC) | P2 | Non-Small Cell Lung Cancer | 150 | Jan 2025 |
| NCT07323641 | Telisotuzumab Vedotin and Osimertinib for the Treatment of Progressive, Incurable, Non Small Cell Lung Cancer | P2 | Lung Non-Small Cell Carcinoma | 60 | Feb 2026 |
Telisotuzumab Vedotin clinical trials by indication
Non-Small Cell Lung Cancer (2)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06093503 | — | P3 | withdrawn | Study of Intravenous Telisotuzumab Vedotin in Combination Osimertinib or Standard of Care Chemotherapy to Assess Change in Disease Activity in Adult Participants With Non-Small Cell Lung Cancer That Has a Mutation in the Epidermal Growth Factor Receptor Gene and That Overexpresses the c-Met Protein |
| NCT06568939 | IV | P2 | recruiting | A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC) |
Non Small Cell Lung Cancer (2)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT04928846 | IV | P3 | recruiting | A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC) |
| NCT05513703 | IV | P2 | terminated | A Study to Assess Disease Activity of Intravenously (IV) Infused Telisotuzumab Vedotin in Adult Participants With Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) |
Lung Non-Small Cell Carcinoma (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07323641 | — | P2 | recruiting | Telisotuzumab Vedotin and Osimertinib for the Treatment of Progressive, Incurable, Non Small Cell Lung Cancer |
Non-small Cell Lung Cancer (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT03539536 | ABBV-399 | P2 | active not recruiting | Study of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung Cancer |
Advanced Solid Tumors Cancer (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT02099058 | PK | P1 | active not recruiting | A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors |
Non-Small Cell Lung Cancer (NSCLC) (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT04830202 | — | N/A | temporarily not available | Expanded Access to Telisotuzumab Vedotin |
Telisotuzumab Vedotin pivotal trial highlights (Phase 2/3/4)
Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.
| Acronym | NCT | Phase | Status | Indication | Enrollment | PubMed |
|---|---|---|---|---|---|---|
| IV | NCT04928846 | P3 | recruiting | Non Small Cell Lung Cancer | 698 | — |
| IV | NCT06568939 | P2 | recruiting | Non-Small Cell Lung Cancer | 150 | — |
| ABBV-399 | NCT03539536 | P2 | active not recruiting | Non-small Cell Lung Cancer | 270 | PMID 38843488 |
| IV | NCT05513703 | P2 | terminated | Non Small Cell Lung Cancer | 9 | — |
Terminated and withdrawn Telisotuzumab Vedotin trials (2)
Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.
- NCT06093503withdrawnStudy of Intravenous Telisotuzumab Vedotin in Combination Osimertinib or Standard of Care Chemotherapy to Assess Change in Disease Activity in Adult Participants With Non-Small Cell Lung Cancer That Has a Mutation in the Epidermal Growth Factor Receptor Gene and That Overexpresses the c-Met Protein
- NCT05513703terminatedA Study to Assess Disease Activity of Intravenously (IV) Infused Telisotuzumab Vedotin in Adult Participants With Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
All Telisotuzumab Vedotin trials (8)
Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.
| NCT ID | Acronym | Title | Phase | Status | Enrollment | Sponsor | Started |
|---|---|---|---|---|---|---|---|
| NCT06093503 | Study of Intravenous Telisotuzumab Vedotin in Combination Osimertinib or Standard of Care Chemotherapy to Assess Change in Disease Activity in Adult Participants With Non-Small Cell Lung Cancer That Has a Mutation in the Epidermal Growth Factor Receptor Gene and That Overexpresses the c-Met Protein | P3 | withdrawn | 0 | AbbVie | May 2024 | |
| NCT04928846 | IV | A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC) | P3 | recruiting | 698 | AbbVie | Mar 2022 |
| NCT06568939 | IV | A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC) | P2 | recruiting | 150 | AbbVie | Jan 2025 |
| NCT07323641 | Telisotuzumab Vedotin and Osimertinib for the Treatment of Progressive, Incurable, Non Small Cell Lung Cancer | P2 | recruiting | 60 | Jonsson Comprehensive Cancer Center | Feb 2026 | |
| NCT03539536 | ABBV-399 | Study of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung Cancer | P2 | active not recruiting | 270 | AbbVie | Oct 2018 |
| NCT02099058 | PK | A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors | P1 | active not recruiting | 237 | AbbVie | Jan 2014 |
| NCT05513703 | IV | A Study to Assess Disease Activity of Intravenously (IV) Infused Telisotuzumab Vedotin in Adult Participants With Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) | P2 | terminated | 9 | AbbVie | Nov 2022 |
| NCT04830202 | Expanded Access to Telisotuzumab Vedotin | — | temporarily not available | 0 | AbbVie | — |
Telisotuzumab Vedotin clinical trials: frequently asked questions
- How many Telisotuzumab Vedotin clinical trials are there?
- 8 Telisotuzumab Vedotin clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 3 are actively recruiting participants.
- Are Telisotuzumab Vedotin clinical trials recruiting in 2026?
- Yes — 3 Telisotuzumab Vedotin trials are actively recruiting in 2026, with 53 U.S. sites across 23 states. See the recruiting trials and the per-state site list further down this page.
- What conditions is Telisotuzumab Vedotin being studied for?
- Telisotuzumab Vedotin is being studied for Non-Small Cell Lung Cancer, Non Small Cell Lung Cancer, Advanced Solid Tumors Cancer, Lung Non-Small Cell Carcinoma, Non-small Cell Lung Cancer and 1 more. The trials are grouped by indication on this page.
- What phase is Telisotuzumab Vedotin in?
- Telisotuzumab Vedotin clinical trials span 2 Phase 3, 4 Phase 2, 1 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
- Who sponsors Telisotuzumab Vedotin clinical trials?
- The lead sponsor across the most Telisotuzumab Vedotin trials is AbbVie, with 1 additional lead sponsor listed in the data. Each trial row links to the full study detail page including sponsor information.
Sources and methodology
Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Telisotuzumab Vedotinas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.
Last refreshed .
Related pages on Hipa.ai: