Telisotuzumab Vedotin Clinical Trials (2026): 8 Studies for Non-Small Cell Lung Cancer & Non Small Cell Lung Cancer

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: .

8 Telisotuzumab Vedotin clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 6 indications (including Non-Small Cell Lung Cancer & Non Small Cell Lung Cancer) and 1,424 total planned enrollment. 2 Phase 3 Telisotuzumab Vedotin trials and 4 Phase 2 are listed. 3 Telisotuzumab Vedotin clinical trials are actively recruiting at 53 U.S. sites across 23 states. Most recent activity: NCT06093503 (Apr 2028).

Where to Participate: All Telisotuzumab Vedotin Trial Sites in the U.S. (53 sites across 23 states)

Every actively recruiting Telisotuzumab Vedotintrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
AZIronwood Cancer and Research Center /ID# 276370Chandler85224NCT06568939Map
ARUniversity of Arkansas for Medical Sciences /ID# 272923Little Rock72205NCT06568939Map
CACity of Hope /ID# 243157Duarte91010NCT04928846Map
CACity Of Hope - Seacliff /ID# 263143Huntington Beach92648NCT04928846Map
CACity of Hope - Orange County Lennar Foundation Cancer Center /ID# 263144Irvine92618NCT04928846Map
CACity Of Hope - Antelope Valley /ID# 263138Lancaster93534NCT04928846Map
CAUCLA / Jonsson Comprehensive Cancer CenterLos Angeles90095NCT07323641Map
CAValkyrie Clinical Trials /ID# 271322Los Angeles90067NCT06568939Map
CAEisenhower Medical Center /ID# 233189Rancho Mirage92270-3221NCT04928846Map
CAPremiere Oncology Foundation /ID# 253954Santa Monica90404NCT04928846Map
CTYale New Haven Hospital /ID# 271584New Haven06510NCT06568939Map
FLCancer Specialists of North Florida - Jacksonville - AC Skinner Parkway /ID# 270899Jacksonville32256NCT06568939Map
FLOcala Oncology Center /ID# 273697Ocala34474NCT06568939Map
FLMemorial Hospital West /ID# 270313Pembroke Pines33028NCT06568939Map
FLComprehensive Hematology Oncology /ID# 270422St. Petersburg33701-4732NCT06568939Map
FLFlorida Cancer Specialists - North /ID# 271995St. Petersburg33705NCT06568939Map
FLFlorida Cancer Specialists - East /ID# 271993West Palm Beach33401NCT06568939Map
GAUniversity Cancer & Blood Center /ID# 270969Athens30607NCT06568939Map
GANorthwest Georgia Oncology Centers /ID# 275374Marietta30060NCT06568939Map
GAMemorial University Medical Center /ID# 272467Savannah31404NCT06568939Map
HIKaiser Permanente Moanalua Medical Center /ID# 238363Honolulu96819-1469NCT04928846Map
HIKaiser Permanente Moanalua Medical Center /ID# 272916Honolulu96819NCT06568939Map
ILUniversity of Illinois Hospital and Health Sciences System /ID# 275345Chicago60607NCT06568939Map
ILIllinois Cancer Specialists /ID# 274678Niles60714NCT06568939Map
ILSpringfield Clinic - First /ID# 272576Springfield62702NCT06568939Map
MSHattiesburg Clinic /ID# 248033Hattiesburg39401NCT04928846Map
MOSt. Lukes Hosp. of Kansas City /ID# 259940Kansas City64111NCT04928846Map
MOHulston Cancer Center /ID# 232226Springfield65807-5287NCT04928846Map
NENHO - Nebraska Hematology-Oncology /ID# 272970Lincoln68506NCT06568939Map
NENebraska Cancer Specialists - Omaha - Wright Street /ID# 271527Omaha68130NCT06568939Map
NVRenown Medical Group - Oncology/Hematology /ID# 247942Reno89502-1464NCT04928846Map
NVRenown Regional Medical Center /ID# 273535Reno89502NCT06568939Map
NJAstera Cancer Care /ID# 272359East Brunswick08816-4096NCT06568939Map
NJRegional Cancer Care Associates /ID# 270783Teaneck07666NCT06568939Map
NYMontefiore Medical Center - Einstein Campus /ID# 277169The Bronx10461NCT06568939Map
NYClinical Research Alliance - Westbury /ID# 270455Westbury11590NCT06568939Map
NCAdventHealth Hendersonville /ID# 265349Hendersonville28792NCT04928846Map
NCFirstHealth of the Carolinas- Speciality Center /ID# 272924Pinehurst28374NCT06568939Map
OHMercy Health - Perrysburg Cancer Center /ID# 270536Perrysburg43551NCT06568939Map
OHGenesis Healthcare System /ID# 273361Zanesville43701NCT06568939Map
PAGuthrie Robert Packer Hospital /ID# 270316Sayre18840NCT06568939Map
PACancer Care Associates Of York /ID# 270971York17403NCT06568939Map
SCMedical University of South Carolina /ID# 251383Charleston29425NCT04928846Map
SCMedical University of South Carolina /ID# 273272Charleston29425NCT06568939Map
SCSaint Francis Cancer Center - Greenville /ID# 276368Greenville29607NCT06568939Map
TNSCRI Oncology Partners /ID# 270162Nashville37203NCT06568939Map
TXTexas Oncology - Dallas - Worth Street /ID# 278947Dallas75246NCT06568939Map
TXTexas Oncology - Northeast Texas /ID# 272000Tyler75702NCT06568939Map
UTCommunity Cancer Trials Of Utah /ID# 276598Ogden84405NCT06568939Map
VAVirginia Cancer Specialists - Fairfax /ID# 272004Fairfax22031NCT06568939Map
WAValley Medical Center /ID# 253950Renton98055-5738NCT04928846Map
WAMedical Oncology Associates - Spokane /ID# 277172Spokane99208NCT06568939Map
WANorthwest Medical Specialties Tacoma /ID# 270534Tacoma98405NCT06568939Map

Telisotuzumab Vedotin clinical trials at a glance: phase × recruitment status

Phaserecruitingactive not recruitingterminatedwithdrawntemporarily not availableTotal
P111
P22114
P3112
N/A11

Recruiting Telisotuzumab Vedotin clinical trials (3)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT04928846IVA Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)P3Non Small Cell Lung Cancer698Mar 2022
NCT06568939IVA Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)P2Non-Small Cell Lung Cancer150Jan 2025
NCT07323641Telisotuzumab Vedotin and Osimertinib for the Treatment of Progressive, Incurable, Non Small Cell Lung CancerP2Lung Non-Small Cell Carcinoma60Feb 2026

Telisotuzumab Vedotin clinical trials by indication

Non-Small Cell Lung Cancer (2)

NCTAcronymPhaseStatusTitle
NCT06093503P3withdrawnStudy of Intravenous Telisotuzumab Vedotin in Combination Osimertinib or Standard of Care Chemotherapy to Assess Change in Disease Activity in Adult Participants With Non-Small Cell Lung Cancer That Has a Mutation in the Epidermal Growth Factor Receptor Gene and That Overexpresses the c-Met Protein
NCT06568939IVP2recruitingA Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer (2)

NCTAcronymPhaseStatusTitle
NCT04928846IVP3recruitingA Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
NCT05513703IVP2terminatedA Study to Assess Disease Activity of Intravenously (IV) Infused Telisotuzumab Vedotin in Adult Participants With Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Lung Non-Small Cell Carcinoma (1)

NCTAcronymPhaseStatusTitle
NCT07323641P2recruitingTelisotuzumab Vedotin and Osimertinib for the Treatment of Progressive, Incurable, Non Small Cell Lung Cancer

Non-small Cell Lung Cancer (1)

NCTAcronymPhaseStatusTitle
NCT03539536ABBV-399P2active not recruitingStudy of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung Cancer

Advanced Solid Tumors Cancer (1)

NCTAcronymPhaseStatusTitle
NCT02099058PKP1active not recruitingA Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors

Non-Small Cell Lung Cancer (NSCLC) (1)

NCTAcronymPhaseStatusTitle
NCT04830202N/Atemporarily not availableExpanded Access to Telisotuzumab Vedotin

Telisotuzumab Vedotin pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

AcronymNCTPhaseStatusIndicationEnrollmentPubMed
IVNCT04928846P3recruitingNon Small Cell Lung Cancer698
IVNCT06568939P2recruitingNon-Small Cell Lung Cancer150
ABBV-399NCT03539536P2active not recruitingNon-small Cell Lung Cancer270PMID 38843488
IVNCT05513703P2terminatedNon Small Cell Lung Cancer9

Terminated and withdrawn Telisotuzumab Vedotin trials (2)

Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.

All Telisotuzumab Vedotin trials (8)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT06093503Study of Intravenous Telisotuzumab Vedotin in Combination Osimertinib or Standard of Care Chemotherapy to Assess Change in Disease Activity in Adult Participants With Non-Small Cell Lung Cancer That Has a Mutation in the Epidermal Growth Factor Receptor Gene and That Overexpresses the c-Met ProteinP3withdrawn0AbbVieMay 2024
NCT04928846IVA Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)P3recruiting698AbbVieMar 2022
NCT06568939IVA Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)P2recruiting150AbbVieJan 2025
NCT07323641Telisotuzumab Vedotin and Osimertinib for the Treatment of Progressive, Incurable, Non Small Cell Lung CancerP2recruiting60Jonsson Comprehensive Cancer CenterFeb 2026
NCT03539536ABBV-399Study of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung CancerP2active not recruiting270AbbVieOct 2018
NCT02099058PKA Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid TumorsP1active not recruiting237AbbVieJan 2014
NCT05513703IVA Study to Assess Disease Activity of Intravenously (IV) Infused Telisotuzumab Vedotin in Adult Participants With Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)P2terminated9AbbVieNov 2022
NCT04830202Expanded Access to Telisotuzumab Vedotintemporarily not available0AbbVie

Telisotuzumab Vedotin clinical trials: frequently asked questions

How many Telisotuzumab Vedotin clinical trials are there?
8 Telisotuzumab Vedotin clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 3 are actively recruiting participants.
Are Telisotuzumab Vedotin clinical trials recruiting in 2026?
Yes — 3 Telisotuzumab Vedotin trials are actively recruiting in 2026, with 53 U.S. sites across 23 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Telisotuzumab Vedotin being studied for?
Telisotuzumab Vedotin is being studied for Non-Small Cell Lung Cancer, Non Small Cell Lung Cancer, Advanced Solid Tumors Cancer, Lung Non-Small Cell Carcinoma, Non-small Cell Lung Cancer and 1 more. The trials are grouped by indication on this page.
What phase is Telisotuzumab Vedotin in?
Telisotuzumab Vedotin clinical trials span 2 Phase 3, 4 Phase 2, 1 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Telisotuzumab Vedotin clinical trials?
The lead sponsor across the most Telisotuzumab Vedotin trials is AbbVie, with 1 additional lead sponsor listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Telisotuzumab Vedotinas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

Last refreshed .

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