How many Saruparib clinical trials are there?

12 Saruparib clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 9 are actively recruiting participants.

Are Saruparib clinical trials recruiting in 2026?

Yes — 9 Saruparib trials are actively recruiting in 2026, with 244 U.S. sites across 37 states. See the recruiting trials and the per-state site list further down this page.

What conditions is Saruparib being studied for?

Saruparib is being studied for Ovarian Cancer, Prostate Cancer, Endometrial Cancer, Biliary Tract Carcinoma, Borderline Resectable Pancreatic Ductal Adenocarcinoma and 21 more. The trials are grouped by indication on this page.

What phase is Saruparib in?

Saruparib clinical trials span 3 Phase 3, 1 Phase 2, 3 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.

Who sponsors Saruparib clinical trials?

The lead sponsor across the most Saruparib trials is AstraZeneca, with 2 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Saruparib Clinical Trials (2026): 12 Studies for Ovarian Cancer & Prostate Cancer

Creator: Hipa.ai Research
Published: 2026-04-29T19:52:43.418Z

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: June 18, 2026.

12 Saruparib clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 11 indications (including Ovarian Cancer & Prostate Cancer) and 5,394 total planned enrollment. 3 Phase 3 Saruparib trials and 1 Phase 2 are listed. 9 Saruparib clinical trials are actively recruiting at 244 U.S. sites across 37 states. Most recent activity: NCT06952803 (Apr 2036).

Where to Participate: All Saruparib Trial Sites in the U.S. (244 sites across 37 states)

Every actively recruiting Saruparibtrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

State	Facility	City	Trial	Map
AZ	Research Site	Gilbert85234	NCT06380751	Map
AZ	Research Site	Phoenix85054	NCT06952803	Map
CA	Research Site	Duarte91010	NCT05797168	Map
CA	Research Site	Fountain Valley92708	NCT06380751	Map
CA	Research Site	Glendale91206	NCT06380751	Map
CA	Research Site	Irvine92618	NCT05797168	Map
CA	Research Site	La Jolla92037	NCT06952803	Map
CA	Research Site	La Jolla92093	NCT06952803	Map
CA	Loma Linda University Medical Center	Loma Linda92354	NCT06769126	Map
CA	Research Site	Los Angeles90089	NCT06380751	Map
CA	Research Site	Los Angeles90048	NCT06952803	Map
CA	Research Site	Newport Beach92663	NCT06380751	Map
CA	Eisenhower Medical Center	Rancho Mirage92270	NCT06769126	Map
CA	University of California Davis Comprehensive Cancer Center	Sacramento95817	NCT06769126	Map
CA	Research Site	San Diego92123	NCT06952803	Map
CA	Research Site	San Luis Obispo93401	NCT06952803	Map
CA	Research Site	Santa Monica90404	NCT05123482	Map
CA	Research Site	Santa Rosa95403	NCT05123482	Map
CO	Research Site	Aurora80045	NCT05797168	Map
CO	Research Site	Aurora80045	NCT06380751	Map
CO	UCHealth University of Colorado Hospital	Aurora80045	NCT06769126	Map
CO	Memorial Hospital North	Colorado Springs80920	NCT06769126	Map
CO	UCHealth Memorial Hospital Central	Colorado Springs80909	NCT06769126	Map
CO	Cancer Care and Hematology-Fort Collins	Fort Collins80528	NCT06769126	Map
CO	Poudre Valley Hospital	Fort Collins80524	NCT06769126	Map
CO	Lutheran Hospital - Cancer Centers of Colorado	Golden80401	NCT06769126	Map
CO	UCHealth Greeley Hospital	Greeley80631	NCT06769126	Map
CO	Research Site	Lakewood80215	NCT06952803	Map
CO	Medical Center of the Rockies	Loveland80538	NCT06769126	Map
CT	Smilow Cancer Hospital-Derby Care Center	Derby06418	NCT06769126	Map
CT	Smilow Cancer Hospital Care Center-Fairfield	Fairfield06824	NCT06769126	Map
CT	Smilow Cancer Hospital Care Center - Guilford	Guilford06437	NCT06769126	Map
CT	Yale University	New Haven06520	NCT06769126	Map
CT	Yale-New Haven Hospital North Haven Medical Center	North Haven06473	NCT06769126	Map
CT	Smilow Cancer Hospital-Torrington Care Center	Torrington06790	NCT06769126	Map
CT	Smilow Cancer Hospital Care Center-Trumbull	Trumbull06611	NCT06769126	Map
CT	Smilow Cancer Hospital-Waterbury Care Center	Waterbury06708	NCT06769126	Map
CT	Smilow Cancer Hospital Care Center - Waterford	Waterford06385	NCT06769126	Map
DE	Helen F Graham Cancer Center	Newark19713	NCT06769126	Map
DE	Medical Oncology Hematology Consultants PA	Newark19713	NCT06769126	Map
FL	Research Site	Hialeah33016	NCT06952803	Map
FL	Research Site	Hollywood33021	NCT06380751	Map
FL	Research Site	Jacksonville32224	NCT06380751	Map
FL	Research Site	Jacksonville32224	NCT06952803	Map
FL	Research Site	Tampa33612	NCT06952803	Map
GA	Research Site	Newnan30265	NCT06952803	Map
GA	Lewis Cancer and Research Pavilion at Saint Joseph's/Candler	Savannah31405	NCT06769126	Map
ID	Kootenai Health - Coeur d'Alene	Coeur d'Alene83814	NCT06769126	Map
ID	Saint Alphonsus Cancer Care Center-Nampa	Nampa83687	NCT06769126	Map
ID	Kootenai Clinic Cancer Services - Post Falls	Post Falls83854	NCT06769126	Map
ID	Kootenai Clinic Cancer Services - Sandpoint	Sandpoint83864	NCT06769126	Map
IL	Northwestern University	Chicago60611	NCT06769126	Map
IL	Research Site	Chicago60611	NCT06380751	Map
IL	Research Site	Chicago60611	NCT06952803	Map
IL	Research Site	Chicago Ridge60415	NCT06952803	Map
IL	Northwestern Medicine Cancer Center Kishwaukee	DeKalb60115	NCT06769126	Map
IL	Research Site	Evanston60201	NCT06380751	Map
IL	Northwestern Medicine Cancer Center Delnor	Geneva60134	NCT06769126	Map
IL	Northwestern Medicine Glenview Outpatient Center	Glenview60026	NCT06769126	Map
IL	Northwestern Medicine Grayslake Outpatient Center	Grayslake60030	NCT06769126	Map
IL	Northwestern Medicine Lake Forest Hospital	Lake Forest60045	NCT06769126	Map
IL	Loyola University Medical Center	Maywood60153	NCT06769126	Map
IL	Northwestern Medicine Oak Brook	Oak Brook60523	NCT06769126	Map
IL	Northwestern Medicine Orland Park	Orland Park60462	NCT06769126	Map
IL	Research Site	Urbana61801	NCT06380751	Map
IL	Northwestern Medicine Cancer Center Warrenville	Warrenville60555	NCT06769126	Map
IL	Research Site	Winfield60190	NCT06380751	Map
IN	Research Site	Greenwood46143	NCT06952803	Map
IA	Mary Greeley Medical Center	Ames50010	NCT06769126	Map
IA	McFarland Clinic - Ames	Ames50010	NCT06769126	Map
IA	UI Health Care Mission Cancer and Blood - Ankeny Clinic	Ankeny50023	NCT06769126	Map
IA	Mercy Hospital	Cedar Rapids52403	NCT06769126	Map
IA	Oncology Associates at Mercy Medical Center	Cedar Rapids52403	NCT06769126	Map
IA	UI Health Care Mission Cancer and Blood - West Des Moines Clinic	Clive50325	NCT06769126	Map
IA	Iowa Methodist Medical Center	Des Moines50309	NCT06769126	Map
IA	Mercy Medical Center - Des Moines	Des Moines50314	NCT06769126	Map
IA	UI Health Care Mission Cancer and Blood - Des Moines Clinic	Des Moines50309	NCT06769126	Map
IA	UI Health Care Mission Cancer and Blood - Laurel Clinic	Des Moines50314	NCT06769126	Map
IA	McFarland Clinic - Trinity Cancer Center	Fort Dodge50501	NCT06769126	Map
IA	McFarland Clinic - Marshalltown	Marshalltown50158	NCT06769126	Map
IA	UI Health Care Mission Cancer and Blood - Waukee Clinic	Waukee50263	NCT06769126	Map
IA	The Iowa Clinic PC	West Des Moines50266	NCT06769126	Map
KS	University of Kansas Clinical Research Center	Fairway66205	NCT06769126	Map
KS	University of Kansas Cancer Center	Kansas City66160	NCT06769126	Map
KS	The University of Kansas Cancer Center - Olathe	Olathe66061	NCT06769126	Map
KS	University of Kansas Cancer Center-Overland Park	Overland Park66210	NCT06769126	Map
KS	Salina Regional Health Center	Salina67401	NCT06769126	Map
KS	University of Kansas Hospital-Westwood Cancer Center	Westwood66205	NCT06769126	Map
KY	Baptist Health Corbin	Corbin40701	NCT06769126	Map
KY	Baptist Health Hamburg	Lexington40509	NCT06769126	Map
KY	Baptist Health Lexington	Lexington40503	NCT06769126	Map
MD	Research Site	Baltimore21231	NCT05123482	Map
MD	University of Maryland/Greenebaum Cancer Center	Baltimore21201	NCT06769126	Map
MD	Research Site	Bethesda20817	NCT06952803	Map
MD	Research Site	Silver Spring20902	NCT06380751	Map
MD	Research Site	Silver Spring20904	NCT06380751	Map
MD	Research Site	Towson21204	NCT06952803	Map
MA	Research Site	Boston02215	NCT05123482	Map
MA	Research Site	Boston02114	NCT05797168	Map
MA	Research Site	Boston02215	NCT06380751	Map
MA	Tufts Medical Center	Boston02111	NCT06769126	Map
MA	Lahey Hospital and Medical Center	Burlington01805	NCT06769126	Map
MA	Lahey Medical Center-Peabody	Peabody01960	NCT06769126	Map
MA	Research Site	Plymouth02360	NCT06952803	Map
MI	Trinity Health IHA Medical Group Hematology Oncology - Brighton	Brighton48114	NCT06769126	Map
MI	Trinity Health IHA Medical Group Hematology Oncology - Canton	Canton48188	NCT06769126	Map
MI	Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital	Chelsea48118	NCT06769126	Map
MI	Henry Ford Health Saint John Hospital	Detroit48236	NCT06769126	Map
MI	Research Site	Detroit48201	NCT05797168	Map
MI	Research Site	Detroit48202	NCT05938270	Map
MI	Research Site	Detroit48202	NCT06380751	Map
MI	Henry Ford River District Hospital	East China Township48054	NCT06769126	—
MI	Henry Ford Saint John Hospital - Academic	Grosse Pointe Woods48236	NCT06769126	Map
MI	Henry Ford Saint John Hospital - Breast	Grosse Pointe Woods48236	NCT06769126	Map
MI	Henry Ford Saint John Hospital - Van Elslander	Grosse Pointe Woods48236	NCT06769126	Map
MI	University of Michigan Health - Sparrow Lansing	Lansing48912	NCT06769126	Map
MI	Trinity Health Saint Mary Mercy Livonia Hospital	Livonia48154	NCT06769126	Map
MI	Henry Ford Saint John Hospital - Macomb Medical	Macomb48044	NCT06769126	Map
MI	Henry Ford Warren Hospital - Breast Macomb	Macomb48044	NCT06769126	Map
MI	Trinity Health Saint Joseph Mercy Oakland Hospital	Pontiac48341	NCT06769126	Map
MI	Research Site	Royal Oak48073	NCT06380751	Map
MI	Henry Ford Health Warren Hospital	Warren48093	NCT06769126	Map
MI	Henry Ford Madison Heights Hospital - Breast	Warren48093	NCT06769126	Map
MI	Henry Ford Warren Hospital - GLCMS	Warren48093	NCT06769126	Map
MI	Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus	Ypsilanti48197	NCT06769126	Map
MN	Sanford Joe Lueken Cancer Center	Bemidji56601	NCT06769126	Map
MN	Essentia Health Saint Joseph's Medical Center	Brainerd56401	NCT06769126	Map
MN	Mercy Hospital	Coon Rapids55433	NCT06769126	Map
MN	Essentia Health - Deer River Clinic	Deer River56636	NCT06769126	Map
MN	Essentia Health Cancer Center	Duluth55805	NCT06769126	Map
MN	Fairview Southdale Hospital	Edina55435	NCT06769126	Map
MN	Essentia Health Hibbing Clinic	Hibbing55746	NCT06769126	Map
MN	Saint John's Hospital - Healtheast	Maplewood55109	NCT06769126	Map
MN	Abbott-Northwestern Hospital	Minneapolis55407	NCT06769126	Map
MN	Hennepin County Medical Center	Minneapolis55415	NCT06769126	Map
MN	New Ulm Medical Center	New Ulm56073	NCT06769126	Map
MN	Research Site	Rochester55905	NCT06380751	Map
MN	Research Site	Rochester55905	NCT06952803	Map
MN	Park Nicollet Clinic - Saint Louis Park	Saint Louis Park55416	NCT06769126	Map
MN	Regions Hospital	Saint Paul55101	NCT06769126	Map
MN	United Hospital	Saint Paul55102	NCT06769126	Map
MN	Essentia Health Sandstone	Sandstone55072	NCT06769126	Map
MN	Essentia Health Virginia Clinic	Virginia55792	NCT06769126	Map
MO	University of Kansas Cancer Center - Briarcliff	Kansas City64116	NCT06769126	Map
MO	University of Kansas Cancer Center - North	Kansas City64154	NCT06769126	Map
MO	University of Kansas Cancer Center - Lee's Summit	Lee's Summit64064	NCT06769126	Map
MO	Research Site	Springfield65804	NCT06380751	Map
MO	Mercy Hospital Saint Louis	St Louis63141	NCT06769126	Map
MO	Mercy Hospital South	St Louis63128	NCT06769126	Map
MO	Research Site	St Louis63110	NCT05123482	Map
MT	Community Hospital of Anaconda	Anaconda59711	NCT06769126	Map
MT	Billings Clinic Cancer Center	Billings59101	NCT06769126	Map
MT	Bozeman Health Deaconess Hospital	Bozeman59715	NCT06769126	Map
MT	Benefis Sletten Cancer Institute	Great Falls59405	NCT06769126	Map
MT	Community Medical Center	Missoula59804	NCT06769126	Map
NJ	Research Site	Camden08103	NCT06380751	Map
NJ	Research Site	Hackensack07601	NCT06952803	Map
NJ	Research Site	Voorhees Township08043	NCT06952803	Map
NM	Research Site	Albuquerque87109	NCT05123482	Map
NY	Roswell Park Cancer Institute	Buffalo14263	NCT06769126	Map
NY	Research Site	Commack11725	NCT05123482	Map
NY	Research Site	Mineola11501	NCT06380751	Map
NY	Research Site	New York10016	NCT06380751	Map
NY	Research Site	New York10065	NCT06380751	Map
NY	Research Site	New York10065	NCT06952803	Map
NY	University of Rochester	Rochester14642	NCT06769126	Map
NY	Research Site	Stony Brook11790	NCT06380751	Map
NY	Research Site	Syracuse13210	NCT06952803	Map
NY	Wilmot Cancer Institute at Webster	Webster14580	NCT06769126	Map
NC	Research Site	Charlotte28204	NCT05123482	Map
NC	FirstHealth of the Carolinas-Moore Regional Hospital	Pinehurst28374	NCT06769126	Map
ND	Sanford Bismarck Medical Center	Bismarck58501	NCT06769126	Map
ND	Essentia Health Cancer Center-South University Clinic	Fargo58103	NCT06769126	Map
ND	Sanford Broadway Medical Center	Fargo58122	NCT06769126	Map
ND	Sanford Roger Maris Cancer Center	Fargo58122	NCT06769126	Map
OH	Aultman Health Foundation	Canton44710	NCT06769126	Map
OH	Miami Valley Hospital South	Centerville45459	NCT06769126	Map
OH	Research Site	Columbus43201	NCT05797168	Map
OH	Research Site	Columbus43230	NCT06952803	Map
OH	Miami Valley Hospital	Dayton45409	NCT06769126	Map
OH	Miami Valley Hospital North	Dayton45415	NCT06769126	Map
OH	Premier Blood and Cancer Center	Dayton45409	NCT06769126	Map
OH	Atrium Medical Center-Middletown Regional Hospital	Franklin45005-1066	NCT06769126	Map
OH	Miami Valley Cancer Care and Infusion	Greenville45331	NCT06769126	Map
OH	Upper Valley Medical Center	Troy45373	NCT06769126	Map
OK	University of Oklahoma Health Sciences Center	Oklahoma City73104	NCT06769126	Map
OR	Providence Newberg Medical Center	Newberg97132	NCT06769126	Map
OR	Providence Willamette Falls Medical Center	Oregon City97045	NCT06769126	Map
OR	OHSU Knight Cancer Institute	Portland97239	NCT04005690	Map
OR	Providence Portland Medical Center	Portland97213	NCT06769126	Map
OR	Providence Saint Vincent Medical Center	Portland97225	NCT06769126	Map
OR	Research Site	Portland97239	NCT05797168	Map
OR	Research Site	Springfield97477	NCT06952803	Map
PA	Research Site	Hershey17033	NCT06380751	Map
PA	Research Site	Hershey17033	NCT06952803	Map
PA	Research Site	Lancaster17601	NCT06952803	Map
PA	Research Site	Philadelphia19104	NCT06380751	Map
PA	Research Site	Pittsburgh15213	NCT05123482	Map
PA	Research Site	Pittsburgh15215	NCT06380751	Map
PA	Research Site	Pittsburgh15212	NCT06952803	Map
RI	Research Site	Providence02903	NCT05797168	Map
RI	Research Site	Providence02905	NCT05797168	Map
RI	Research Site	Providence02903	NCT05938270	Map
RI	Research Site	Providence02903	NCT06952803	Map
SC	Saint Joseph's/Candler - Bluffton Campus	Bluffton29910	NCT06769126	Map
SC	Prisma Health Cancer Institute - Spartanburg	Boiling Springs29316	NCT06769126	Map
SC	Prisma Health Cancer Institute - Easley	Easley29640	NCT06769126	Map
SC	Tidelands Georgetown Memorial Hospital	Georgetown29440	NCT06769126	Map
SC	Prisma Health Cancer Institute - Butternut	Greenville29605	NCT06769126	Map
SC	Prisma Health Cancer Institute - Eastside	Greenville29615	NCT06769126	Map
SC	Prisma Health Cancer Institute - Faris	Greenville29605	NCT06769126	Map
SC	Prisma Health Cancer Institute - Greer	Greer29650	NCT06769126	Map
SC	Research Site	Myrtle Beach29572	NCT06952803	Map
SC	Prisma Health Cancer Institute - Seneca	Seneca29672	NCT06769126	Map
SD	Sanford Cancer Center Oncology Clinic	Sioux Falls57104	NCT06769126	Map
SD	Sanford USD Medical Center - Sioux Falls	Sioux Falls57117-5134	NCT06769126	Map
TN	Research Site	Chattanooga37404	NCT06380751	Map
TN	Research Site	Nashville37203	NCT06380751	Map
TN	Research Site	Nashville37209	NCT06952803	Map
TX	Research Site	Austin78705	NCT06952803	Map
TX	Research Site	Austin78745	NCT06952803	Map
TX	M D Anderson Cancer Center	Houston77030	NCT06769126	Map
TX	Research Site	Houston77030	NCT05123482	Map
TX	Research Site	Houston77030	NCT05797168	Map
TX	Research Site	Houston77030	NCT06380751	Map
TX	Research Site	Houston77054	NCT06380751	Map
TX	Research Site	Houston77074	NCT06952803	Map
TX	Research Site	San Antonio78240	NCT06380751	Map
TX	Research Site	San Antonio78229	NCT06952803	Map
TX	Research Site	Spring77380	NCT06952803	Map
VA	Research Site	Fairfax22031	NCT05797168	Map
VA	Research Site	Fairfax22031	NCT07446855	Map
VA	Research Site	Norfolk23502	NCT06380751	Map
VA	Research Site	Norfolk23502	NCT06952803	Map
VA	VCU Massey Cancer Center at Stony Point	Richmond23235	NCT06769126	Map
VA	VCU Massey Comprehensive Cancer Center	Richmond23298	NCT06769126	Map
VA	Research Site	Roanoke24014	NCT06952803	Map
VA	VCU Community Memorial Health Center	South Hill23970	NCT06769126	Map
VA	VCU Health Tappahannock Hospital	Tappahannock22560	NCT06769126	Map
VA	Research Site	Virginia Beach23462	NCT06952803	Map
WA	Research Site	Tacoma98405	NCT06380751	Map
WV	Research Site	Morgantown26506	NCT06380751	Map
WI	Duluth Clinic Ashland	Ashland54806	NCT06769126	Map
WI	Gundersen Lutheran Medical Center	La Crosse54601	NCT06769126	Map

Saruparib clinical trials at a glance: phase × recruitment status

Phase	recruiting	active not recruiting	withdrawn	Total
Early P1	1			1
P1	2	1		3
P1/P2	3		1	4
P2	1			1
P3	2	1		3

Recruiting Saruparib clinical trials (9)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT ID	Title	Phase	Indication	Enrollment	Started
NCT06952803	EvoPAR-PR02A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation	P3	Prostate Cancer	700	Aug 2025
NCT06380751	EvoPAR-BR01Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer	P3	Advanced Breast Cancer	500	Aug 2024
NCT07446855	PARTHENONStudy of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours	P1/P2	Solid Tumours	180	Mar 2026
NCT06769126	Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study	P2	Extensive Stage Lung Small Cell Carcinoma	900	Nov 2025
NCT04005690	Targeted Pathway Inhibition in Patients With Pancreatic Cancer	Early P1	Locally Advanced Pancreatic Ductal Adenocarcinoma	90	Aug 2019
NCT05797168	FONTANAPhase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors	P1/P2	Ovarian Cancer	506	Jun 2023
NCT05123482	A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies	P1/P2	Breast Cancer	460	Oct 2021
NCT06713369	AZD5305AZD5305 hADME in Patients With Advanced Solid Malignancies	P1	Locally Advanced or Metastatic Solid Tumor	8	Apr 2025
NCT05938270	ASCERTAINA Study to Investigate the Biological Effects of Saruparib (AZD5305), Darolutamide, and in Combination in Men With Newly Diagnosed Prostate Cancer.	P1	Prostate Cancer	120	Sep 2023

Saruparib clinical trials by indication

Prostate Cancer (2)

NCT	Acronym	Phase	Status	Title
NCT06952803	EvoPAR-PR02	P3	recruiting	A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation
NCT05938270	ASCERTAIN	P1	recruiting	A Study to Investigate the Biological Effects of Saruparib (AZD5305), Darolutamide, and in Combination in Men With Newly Diagnosed Prostate Cancer.

Solid Tumours (1)

NCT	Acronym	Phase	Status	Title
NCT07446855	PARTHENON	P1/P2	recruiting	Study of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours

Extensive Stage Lung Small Cell Carcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT06769126	—	P2	recruiting	Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

Advanced/Recurrent Ovarian Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT07060365	—	P1/P2	withdrawn	A Master Protocol Study to Investigate Biomarker-guided Novel Anticancer Agent(s) as Monotherapy or Combination Therapy in Participants With Advanced/Recurrent Ovarian Cancer

Locally Advanced or Metastatic Solid Tumor (1)

NCT	Acronym	Phase	Status	Title
NCT06713369	AZD5305	P1	recruiting	AZD5305 hADME in Patients With Advanced Solid Malignancies

Advanced Solid Malignancies (1)

NCT	Acronym	Phase	Status	Title
NCT06899061	—	P1	active not recruiting	Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib

Advanced Breast Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT06380751	EvoPAR-BR01	P3	recruiting	Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Metastatic Castration-Sensitive Prostate Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT06120491	EvoPAR-PR01	P3	active not recruiting	Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents

Ovarian Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT05797168	FONTANA	P1/P2	recruiting	Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

Breast Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT05123482	—	P1/P2	recruiting	A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

Locally Advanced Pancreatic Ductal Adenocarcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT04005690	—	Early P1	recruiting	Targeted Pathway Inhibition in Patients With Pancreatic Cancer

Saruparib pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

Acronym	NCT	Phase	Status	Indication	Enrollment	PubMed
EvoPAR-PR02	NCT06952803	P3	recruiting	Prostate Cancer	700	—
EvoPAR-PR01	NCT06120491	P3	active not recruiting	Metastatic Castration-Sensitive Prostate Cancer	1,889	—
EvoPAR-BR01	NCT06380751	P3	recruiting	Advanced Breast Cancer	500	—

Terminated and withdrawn Saruparib trials (1)

Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.

NCT07060365withdrawnA Master Protocol Study to Investigate Biomarker-guided Novel Anticancer Agent(s) as Monotherapy or Combination Therapy in Participants With Advanced/Recurrent Ovarian Cancer

All Saruparib trials (12)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT ID	Acronym	Title	Phase	Status	Enrollment	Sponsor	Started
NCT06952803	EvoPAR-PR02	A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation	P3	recruiting	700	AstraZeneca	Aug 2025
NCT06120491	EvoPAR-PR01	Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents	P3	active not recruiting	1,889	AstraZeneca	Nov 2023
NCT06380751	EvoPAR-BR01	Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer	P3	recruiting	500	AstraZeneca	Aug 2024
NCT07446855	PARTHENON	Study of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours	P1/P2	recruiting	180	AstraZeneca	Mar 2026
NCT06769126		Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study	P2	recruiting	900	SWOG Cancer Research Network	Nov 2025
NCT04005690		Targeted Pathway Inhibition in Patients With Pancreatic Cancer	Early P1	recruiting	90	OHSU Knight Cancer Institute	Aug 2019
NCT05797168	FONTANA	Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors	P1/P2	recruiting	506	AstraZeneca	Jun 2023
NCT05123482		A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies	P1/P2	recruiting	460	AstraZeneca	Oct 2021
NCT06713369	AZD5305	AZD5305 hADME in Patients With Advanced Solid Malignancies	P1	recruiting	8	AstraZeneca	Apr 2025
NCT05938270	ASCERTAIN	A Study to Investigate the Biological Effects of Saruparib (AZD5305), Darolutamide, and in Combination in Men With Newly Diagnosed Prostate Cancer.	P1	recruiting	120	AstraZeneca	Sep 2023
NCT06899061		Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib	P1	active not recruiting	41	AstraZeneca	Mar 2025
NCT07060365		A Master Protocol Study to Investigate Biomarker-guided Novel Anticancer Agent(s) as Monotherapy or Combination Therapy in Participants With Advanced/Recurrent Ovarian Cancer	P1/P2	withdrawn	0	AstraZeneca	Sep 2025

Saruparib clinical trials: frequently asked questions

How many Saruparib clinical trials are there?: 12 Saruparib clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 9 are actively recruiting participants.
Are Saruparib clinical trials recruiting in 2026?: Yes — 9 Saruparib trials are actively recruiting in 2026, with 244 U.S. sites across 37 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Saruparib being studied for?: Saruparib is being studied for Ovarian Cancer, Prostate Cancer, Endometrial Cancer, Biliary Tract Carcinoma, Borderline Resectable Pancreatic Ductal Adenocarcinoma and 21 more. The trials are grouped by indication on this page.
What phase is Saruparib in?: Saruparib clinical trials span 3 Phase 3, 1 Phase 2, 3 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Saruparib clinical trials?: The lead sponsor across the most Saruparib trials is AstraZeneca, with 2 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Saruparibas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

Last refreshed June 18, 2026.

Related pages on Hipa.ai:

Saruparib overview