Ritlecitinib Clinical Trials (2026): 25 Studies for Alopecia Areata & Healthy Volunteers

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: .

25 Ritlecitinib clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 13 indications (including Alopecia Areata & Healthy Volunteers) and 5,618 total planned enrollment. 6 Phase 3 Ritlecitinib trials and 7 Phase 2 are listed. 7 Ritlecitinib clinical trials are actively recruiting at 81 U.S. sites across 29 states. Most recent activity: NCT07029828 (Jun 2030).

Where to Participate: All Ritlecitinib Trial Sites in the U.S. (81 sites across 29 states)

Every actively recruiting Ritlecitinibtrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
ALC2 Research CenterMontgomery36117NCT06531109Map
AZMedical Dermatology SpecialistsPhoenix85006NCT07228390Map
ARBurke Pharmaceutical ResearchHot Springs71913NCT07228390Map
CAKern Research. Inc.Bakersfield93301NCT07219615Map
CACalifornia Dermatology & Clinical Research InstituteEncinitas92024NCT07029711Map
CACalifornia Dermatology & Clinical Research InstituteEncinitas92024NCT07029828Map
CACENTER FOR DERMATOLOGY CLINICAL RESEARCH, IncFremont94538NCT06531109Map
CARao DermatologyFresno93720NCT06531109Map
CAUniversity of California - IrvineIrvine92617NCT07029711Map
CAAntelope Valley Clinical TrialsLancaster93534NCT07219615Map
CANorthridge Clinical TrialsNorthridge91325NCT07228390Map
CACura Clinical ResearchOxnard93030NCT06531109Map
CASkin & Beauty Center - PasadenaPasadena91105NCT07219615Map
CAInvestigational Drug Service - Rady Children's Hospital-San DiegoSan Diego92123NCT07029711Map
CAUniversity of California, San Diego/Rady Children's Hospital-San Diego;San Diego92123NCT07029711Map
CASouthern California Clinical ResearchSanta Ana92701NCT06531109Map
CASouthern California Clinical ResearchSanta Ana92701NCT07029711Map
COChildren's Hospital ColoradoAurora80045NCT07029711Map
DCChildren's National Medical CenterWashington D.C.20010NCT07029711Map
FLDermatology of BocaBoca Raton33431NCT06531109Map
FLPediatric Skin Research,LLCCoral Gables33146NCT06531109Map
FLSuncoast Skin SolutionsJacksonville32256NCT06531109Map
FLPediatric Skin ResearchMiami33156NCT07029711Map
FLPediatric Skin ResearchMiami33156NCT07029828Map
FLSkin Research of South Florida LLCMiami33173NCT06531109Map
FLUniversity of MiamiMiami33136NCT06531109Map
FLD&H Tamarac Research CenterTamarac33321NCT07029711Map
FLD&H Tamarac Research CenterTamarac33321NCT07228390Map
ILAsthma and Allergy Center of ChicagoRiver Forest60305NCT07219615Map
ILEndeavor Health Clinical OperationsSkokie60077NCT07029711Map
INDawes Fretzin Clinical Research Group, LLCIndianapolis46250NCT07029711Map
INDawes Fretzin Clinical Research Group, LLCIndianapolis46250NCT07029828Map
INOptions Research GroupWest Lafayette47906NCT07228390Map
KSEssential Medical Research - Overland ParkOverland Park66213NCT07228390Map
KSSkin and Hair CenterOverland Park66213NCT07228390Map
KYEquity Medical - Bowling GreenBowling Green42104NCT07029711Map
MDKindred Hair and Skin CenterMarriottsville21104NCT06531109Map
MDKindred Hair and Skin CenterMarriottsville21104NCT07029711Map
MDChesapeake Clinical ResearchWhite Marsh21162NCT07219615Map
MABrigham & Women's Hospital/Harvard Medical SchoolBoston02115NCT06531109Map
MIOakland Hills DermatologyAuburn Hills48326NCT06531109Map
MIRevival Research Institute, LLCTroy48084NCT07219615Map
MIRevival Research Institute, LLCTroy48084NCT07228390Map
MIMichigan Dermatology InstituteWaterford48328NCT06531109Map
MIMichigan Dermatology InstituteWaterford48328NCT07029711Map
MNUniversity of Minnesota Health Clinical Research Unit (M Health CRU)Minneapolis55455NCT07029711Map
NEEar, Nose & Throat Consultants, LLCOmaha68144NCT07029828Map
NEEar, Nose and Throat Consultants, LLCOmaha68144NCT07029711Map
NESkin Specialists, PC dba Schlessinger MDOmaha68144NCT07029711Map
NESkin Specialists, PC dba Schlessinger MDOmaha68144NCT07029828Map
NEComplete Behavior Health (Dr. Brittany Marshall, Licensed Psychologist)Papillion68046NCT07029711Map
NEComplete Behavior Health (Dr. Brittany Marshall, Licensed Psychologist)Papillion68046NCT07029828Map
NHStracskinPortsmouth03801NCT07228390Map
NMRegents of the University of New MexicoAlbuquerque87131NCT07029711Map
NMRegents of the University of New MexicoAlbuquerque87131NCT07029828Map
NMUniversity of New Mexico Health Sciences CenterAlbuquerque87102NCT07029711Map
NMUniversity of New Mexico Health Sciences CenterAlbuquerque87102NCT07029828Map
NMUniversity of New Mexico-IDS PharmacyAlbuquerque87106NCT07029711Map
NMUniversity of New Mexico-IDS PharmacyAlbuquerque87106NCT07029828Map
NYEquity MedicalNew York10455NCT07029711Map
NYIcahn School of Medicine at Mount SinaiNew York10029NCT06373458Map
NCHickory Dermatology Research CenterHickory28602NCT06531109Map
OKAllergy, Asthma, & Clinical Research CenterOklahoma City73120NCT07219615Map
ORNorthwest Dermatology InstitutePortland97210NCT07029711Map
ORNorthwest Dermatology InstitutePortland97210NCT07029828Map
ORNW Dermatology InstitutePortland97210NCT06531109Map
PAPenn State Health Milton S. Hershey Medical CenterHershey17033NCT07029711Map
PAUPMCPittsburgh15213NCT06531109Map
SCMedical University of South Carolina Department of Dermatology and Dermatologic SurgeryCharleston29425NCT07029711Map
TNGoodlettsville Dermatology ResearchGoodlettsville37072NCT06531109Map
TXDriscoll Children's HospitalCorpus Christi78411NCT07029711Map
TX3A ResearchEl Paso79902NCT07029828Map
TXAustin Institute for Clinical ResearchPflugerville78660NCT07029711Map
TXTexas Dermatology and Laser SpecialistsSan Antonio78218NCT07029711Map
TXTexas Dermatology and Laser SpecialistsSan Antonio78218NCT07029828Map
TXEpiphany DermatologySouthlake76092NCT06531109Map
TXComplete DermatologySugar Land77479NCT07219615Map
VARaven Clinical ReseachFairfax22033NCT06531109Map
VARaven Clinical ReseachMcLean22102NCT06531109Map
WAFrontier DermatologyMill Creek98012NCT06531109Map
WIRaven Clinical ReseachBurlington53105NCT06531109Map

Ritlecitinib clinical trials at a glance: phase × recruitment status

Phaserecruitingactive not recruitingcompletedterminatedwithdrawnavailableTotal
P177
P2311117
P32316
N/A21115

Recruiting Ritlecitinib clinical trials (7)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT07029828B7981028A Long-Term Study to Learn About The Study Medicine Called Ritlecitinib in Children With Severe Alopecia Areata.P3Severe Alopecia Areata140Sep 2025
NCT06531109PRESTOCharacterization And Clinical Outcomes of AA Patients Treated With RitlecitinibAlopecia Areata850Aug 2024
NCT06373458Ritlecitinib in Patients With Keloids or Those Undergoing KeloidectomyP2Keloid30Aug 2024
NCT07029711B7981027A Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia AreataP3Severe Alopecia Areata225Jul 2025
NCT07219615A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.P2Chronic Spontaneous Urticaria200Oct 2025
NCT07228390A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.P2Hidradenitis Suppurativa240Nov 2025
NCT06573593Efficacy and Safety of JAK Inhibitors in Patients With AA: RWE StudyAlopecia Areata150Jul 2024

Ritlecitinib clinical trials by indication

Alopecia Areata (6)

NCTAcronymPhaseStatusTitle
NCT06531109PRESTON/ArecruitingCharacterization And Clinical Outcomes of AA Patients Treated With Ritlecitinib
NCT06573593N/ArecruitingEfficacy and Safety of JAK Inhibitors in Patients With AA: RWE Study
NCT06873945ALLEGRO-100P3active not recruitingA Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia Areata
NCT07226531N/Aactive not recruitingUtilization and Effectiveness of Ritlecitinib in a Real-World Population With Severe AA in the US
NCT05650333AAP1completedA Study to Learn About the Study Medicine (Called Ritlecitinib) For the Potential Treatment of Severe Alopecia Areata (AA) In Children 6 To Less Than 12 Years of Age
NCT05522556PF-06651600N/AavailablePre-approval Single-patient Expanded Access for Ritlecitinib (PF-06651600)

Healthy Volunteers (4)

NCTAcronymPhaseStatusTitle
NCT06369454P1completedA Study to Learn About How Different Forms of the Study Medicine Called Ritlecitinib Pass the Intestines of Healthy Male Adults When Taken With or Without Food
NCT06172348P1completedA Study to Learn About Three Forms of The Study Medicine (Ritlecitinib) in Healthy Adults
NCT05852340P1completedA Study to Assess Two Forms of The Study Medicine (Ritlecitinib) in Healthy Adult Participants
NCT05097716PKP1completedStudy to Evaluate the Effect of Multiple-Dose Ritlecitinib on the Pharmacokinetics (PK) of Tolbutamide

Severe Alopecia Areata (3)

NCTAcronymPhaseStatusTitle
NCT07029828B7981028P3recruitingA Long-Term Study to Learn About The Study Medicine Called Ritlecitinib in Children With Severe Alopecia Areata.
NCT07029711B7981027P3recruitingA Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia Areata
NCT07200128N/AcompletedA Study to Learn About the Medicine Called Ritlecitinib in Adults With Severe Alopecia Areata in Real-world Settings

Chronic Spontaneous Urticaria (2)

NCTAcronymPhaseStatusTitle
NCT07219615P2recruitingA Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.
NCT06795373PF-06651600P2withdrawnRitlecitinib (PF-06651600) in Participants With Chronic Spontaneous Urticaria

Stable Nonsegmental Vitiligo (2)

NCTAcronymPhaseStatusTitle
NCT06072183Tranquillo 2P3active not recruitingA 104-Week Study of Ritlecitinib Oral Capsules in Adults With Nonsegmental Vitiligo (Active and Stable) Tranquillo 2
NCT05583526TranquilloP3completedA 52-Week Study of Ritlecitinib Oral Capsules in Adults and Adolescents With Nonsegmental Vitiligo (Active and Stable) Tranquillo

Hidradenitis Suppurativa (1)

NCTAcronymPhaseStatusTitle
NCT07228390P2recruitingA 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.

Keloid (1)

NCTAcronymPhaseStatusTitle
NCT06373458P2recruitingRitlecitinib in Patients With Keloids or Those Undergoing Keloidectomy

Vitiligo (1)

NCTAcronymPhaseStatusTitle
NCT06163326Tranquillo LTEP3active not recruitingA 52-Week Study to Learn About the Safety and Effects of Ritlecitinib in Participants With Nonsegmental Vitiligo

Diabetes Mellitus, Type 1 (1)

NCTAcronymPhaseStatusTitle
NCT05743244JAKP2active not recruitingJanus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)

CTCL (1)

NCTAcronymPhaseStatusTitle
NCT05879458P2terminatedRitlecitinib in CTCL

Celiac Disease (1)

NCTAcronymPhaseStatusTitle
NCT05636293P2completedDouble Blind, Placebo-controlled Trial to Establish Safety and Efficacy of Ritlecitinib in Celiac Disease Patients in Remission

Healthy (1)

NCTAcronymPhaseStatusTitle
NCT05128058P1completedA Target Occupancy Study With Ritlecitinib.

Healthy Participants (1)

NCTAcronymPhaseStatusTitle
NCT05040295P1completedA Single Dose Study To Test Two Pediatric Forms Of Ritlecitinib Compared With Adult Ritlecitinib In Healthy Adults

Ritlecitinib pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

AcronymNCTPhaseStatusIndicationEnrollmentPubMed
B7981028NCT07029828P3recruitingSevere Alopecia Areata140
Tranquillo 2NCT06072183P3active not recruitingStable Nonsegmental Vitiligo1,571
B7981027NCT07029711P3recruitingSevere Alopecia Areata225
Tranquillo LTENCT06163326P3active not recruitingVitiligo394
ALLEGRO-100NCT06873945P3active not recruitingAlopecia Areata550PMID 41083802
TranquilloNCT05583526P3completedStable Nonsegmental Vitiligo607
JAKNCT05743244P2active not recruitingDiabetes Mellitus, Type 178
PF-06651600NCT06795373P2withdrawnChronic Spontaneous Urticaria0

Terminated and withdrawn Ritlecitinib trials (2)

Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.

All Ritlecitinib trials (25)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT07029828B7981028A Long-Term Study to Learn About The Study Medicine Called Ritlecitinib in Children With Severe Alopecia Areata.P3recruiting140PfizerSep 2025
NCT06531109PRESTOCharacterization And Clinical Outcomes of AA Patients Treated With Ritlecitinibrecruiting850PfizerAug 2024
NCT06373458Ritlecitinib in Patients With Keloids or Those Undergoing KeloidectomyP2recruiting30Icahn School of Medicine at Mount SinaiAug 2024
NCT06072183Tranquillo 2A 104-Week Study of Ritlecitinib Oral Capsules in Adults With Nonsegmental Vitiligo (Active and Stable) Tranquillo 2P3active not recruiting1,571PfizerNov 2023
NCT05743244JAKJanus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)P2active not recruiting78National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Oct 2023
NCT07029711B7981027A Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia AreataP3recruiting225PfizerJul 2025
NCT07219615A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.P2recruiting200PfizerOct 2025
NCT07228390A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.P2recruiting240PfizerNov 2025
NCT06163326Tranquillo LTEA 52-Week Study to Learn About the Safety and Effects of Ritlecitinib in Participants With Nonsegmental VitiligoP3active not recruiting394PfizerJan 2024
NCT06573593Efficacy and Safety of JAK Inhibitors in Patients With AA: RWE Studyrecruiting150Second Affiliated Hospital, School of Medicine, Zhejiang UniversityJul 2024
NCT06873945ALLEGRO-100A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia AreataP3active not recruiting550PfizerApr 2025
NCT07226531Utilization and Effectiveness of Ritlecitinib in a Real-World Population With Severe AA in the USactive not recruiting300PfizerDec 2025
NCT05636293Double Blind, Placebo-controlled Trial to Establish Safety and Efficacy of Ritlecitinib in Celiac Disease Patients in RemissionP2completed62Massachusetts General HospitalMar 2023
NCT06795373PF-06651600Ritlecitinib (PF-06651600) in Participants With Chronic Spontaneous UrticariaP2withdrawn0Ahuva D CicesDec 2025
NCT05583526TranquilloA 52-Week Study of Ritlecitinib Oral Capsules in Adults and Adolescents With Nonsegmental Vitiligo (Active and Stable) TranquilloP3completed607PfizerDec 2022
NCT05879458Ritlecitinib in CTCLP2terminated7Icahn School of Medicine at Mount SinaiMay 2023
NCT07200128A Study to Learn About the Medicine Called Ritlecitinib in Adults With Severe Alopecia Areata in Real-world Settingscompleted123PfizerFeb 2025
NCT06369454A Study to Learn About How Different Forms of the Study Medicine Called Ritlecitinib Pass the Intestines of Healthy Male Adults When Taken With or Without FoodP1completed12PfizerMay 2024
NCT06172348A Study to Learn About Three Forms of The Study Medicine (Ritlecitinib) in Healthy AdultsP1completed12PfizerFeb 2024
NCT05650333AAA Study to Learn About the Study Medicine (Called Ritlecitinib) For the Potential Treatment of Severe Alopecia Areata (AA) In Children 6 To Less Than 12 Years of AgeP1completed15PfizerMar 2023
NCT05852340A Study to Assess Two Forms of The Study Medicine (Ritlecitinib) in Healthy Adult ParticipantsP1completed12PfizerMay 2023
NCT05522556PF-06651600Pre-approval Single-patient Expanded Access for Ritlecitinib (PF-06651600)available0Pfizer
NCT05128058A Target Occupancy Study With Ritlecitinib.P1completed16PfizerOct 2021
NCT05097716PKStudy to Evaluate the Effect of Multiple-Dose Ritlecitinib on the Pharmacokinetics (PK) of TolbutamideP1completed12PfizerNov 2021
NCT05040295A Single Dose Study To Test Two Pediatric Forms Of Ritlecitinib Compared With Adult Ritlecitinib In Healthy AdultsP1completed12PfizerSep 2021

Ritlecitinib clinical trials: frequently asked questions

How many Ritlecitinib clinical trials are there?
25 Ritlecitinib clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 7 are actively recruiting participants. 10 are marked completed.
Are Ritlecitinib clinical trials recruiting in 2026?
Yes — 7 Ritlecitinib trials are actively recruiting in 2026, with 81 U.S. sites across 29 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Ritlecitinib being studied for?
Ritlecitinib is being studied for Alopecia Areata, Healthy Volunteers, Severe Alopecia Areata, Active Nonsegmental Vitiligo, Chronic Spontaneous Urticaria and 15 more. The trials are grouped by indication on this page.
What phase is Ritlecitinib in?
Ritlecitinib clinical trials span 6 Phase 3, 7 Phase 2, 7 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Ritlecitinib clinical trials?
The lead sponsor across the most Ritlecitinib trials is Pfizer, with 5 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Ritlecitinibas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

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