LY3549492 Clinical Trials (2026): 9 Studies for Healthy & Obesity
Hipa.ai Research · Source: ClinicalTrials.gov / AACT
Synced daily from ClinicalTrials.gov via AACT. Last sync: .
9 LY3549492 clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 5 indications (including Healthy & Obesity) and 2,170 total planned enrollment. 1 LY3549492 clinical trial is actively recruiting at 49 U.S. sites across 22 states. Most recent activity: NCT06143956 (Feb 2028).
Where to Participate: All LY3549492 Trial Sites in the U.S. (49 sites across 22 states)
Every actively recruiting LY3549492trial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.
| State | Facility | City | Trial | Map |
|---|---|---|---|---|
| AZ | The Institute for Liver Health II dba Arizona Clinical Trials - Mesa | Chandler85225 | NCT06143956 | Map |
| AZ | HOPE Research Institute | Phoenix85032 | NCT06143956 | Map |
| AZ | Headlands Research - Scottsdale | Scottsdale85260 | NCT06143956 | Map |
| AZ | The Institute for Liver Health II dba Arizona Liver Health-Tucson | Tucson85712 | NCT06143956 | Map |
| CA | NorCal Medical Research, Inc | Greenbrae94904 | NCT06143956 | Map |
| CA | Velocity Clinical Research, Huntington Park | Huntington Park90255 | NCT06143956 | Map |
| CA | Peninsula Research Associates | Rolling Hills Estates90274 | NCT06143956 | Map |
| CA | Diablo Clinical Research, Inc. | Walnut Creek94598 | NCT06143956 | Map |
| CT | Stamford Therapeutics Consortium | Stamford06905 | NCT06143956 | Map |
| FL | Northeast Research Institute (NERI) | Fleming Island32003 | NCT06143956 | Map |
| FL | Indago Research & Health Center, Inc | Hialeah33012 | NCT06143956 | Map |
| FL | New Horizon Research Center | Miami33165 | NCT06143956 | Map |
| FL | Suncoast Clinical Research, Inc. | New Port Richey34652 | NCT06143956 | Map |
| FL | Charter Research - Winter Park | Orlando32803 | NCT06143956 | Map |
| FL | Charter Research - Lady Lake | The Villages32162 | NCT06143956 | Map |
| HI | Pacific Diabetes & Endocrine Center | Honolulu96817 | NCT06143956 | Map |
| ID | Medical Research Partners | Ammon83406 | NCT06143956 | Map |
| IL | Great Lakes Clinical Trials - Ravenswood | Chicago60640 | NCT06143956 | Map |
| IL | NorthShore University Health System | Skokie60077 | NCT06143956 | Map |
| IA | Iowa Diabetes and Endocrinology Research Center | West Des Moines50266 | NCT06143956 | Map |
| KS | Cotton O'Neil Diabetes & Endocrinology | Topeka66606 | NCT06143956 | Map |
| KY | Monroe Biomedical Research - Louisville | Louisville40213 | NCT06143956 | Map |
| MA | Knownwell | Needham02492 | NCT06143956 | Map |
| MA | Lucida Clinical Trials | New Bedford02740 | NCT06143956 | Map |
| MI | Headlands Research - Detroit | Southfield48034 | NCT06143956 | Map |
| MI | Arcturus Healthcare , PLC, Troy Internal Medicine Research Division | Troy48098 | NCT06143956 | Map |
| MO | StudyMetrix Research | City of Saint Peters63303 | NCT06143956 | Map |
| MO | Clinvest Headlands Llc | Springfield65807 | NCT06143956 | Map |
| NV | Las Vegas Medical Research | Las Vegas89128 | NCT06143956 | Map |
| NY | Dent Neurologic Institute | Amherst14226 | NCT06143956 | Map |
| NY | Velocity Clinical Research, Syracuse | East Syracuse13057 | NCT06143956 | Map |
| NY | North Suffolk Neurology | Port Jefferson Station11776 | NCT06143956 | Map |
| NY | Rochester Clinical Research, LLC | Rochester14609 | NCT06143956 | Map |
| NC | Medication Management | Greensboro27405 | NCT06143956 | Map |
| NC | Monroe Biomedical Research | Monroe28112 | NCT06143956 | Map |
| NC | Lucas Research, Inc | Morehead City28557 | NCT06143956 | Map |
| NC | Lucas Research, Inc. | New Bern28562 | NCT06143956 | Map |
| OH | CTI Clinical Research Center | Cincinnati45212 | NCT06143956 | Map |
| SC | Tribe Clinical Research, LLC | Greenville29607 | NCT06143956 | Map |
| TN | Quality Medical Research | Nashville37211 | NCT06143956 | Map |
| TX | IMA Clinical Research Austin | Austin78745 | NCT06143956 | Map |
| TX | FutureSearch Trials of Dallas | Dallas75251 | NCT06143956 | Map |
| TX | Velocity Clinical Research, Dallas | Dallas75230 | NCT06143956 | Map |
| TX | PlanIt Research, PLLC | Houston77079 | NCT06143956 | Map |
| TX | Endeavor Clinical Trials | San Antonio78240 | NCT06143956 | Map |
| TX | Tekton Research - Fredericksburg Road | San Antonio78258 | NCT06143956 | Map |
| TX | Texas Valley Clinical Research | Weslaco78596 | NCT06143956 | Map |
| VA | Sovah Clinical Research-River District | Danville24541 | NCT06143956 | Map |
| WA | Central Washington Health Services Association d/b/a Confluence Health | Wenatchee98801 | NCT06143956 | Map |
LY3549492 clinical trials at a glance: phase × recruitment status
| Phase | recruiting | active not recruiting | completed | terminated | Total |
|---|---|---|---|---|---|
| P1 | 1 | 5 | 6 | ||
| P2 | 1 | 1 | 1 | 3 |
Recruiting LY3549492 clinical trials (1)
Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).
| NCT ID | Title | Phase | Indication | Enrollment | Started |
|---|---|---|---|---|---|
| NCT06143956 | LY900038A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight | P2 | Obesity | 1,481 | Nov 2023 |
LY3549492 clinical trials by indication
Healthy (4)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07232732 | — | P1 | active not recruiting | A Study of LY3549492 in Healthy Participants and Participants With Overweight or Obesity |
| NCT06869018 | T2D | P1 | completed | A Study of LY3549492 in Japanese Participants With Type 2 Diabetes Mellitus (T2D) and Healthy Japanese Participants |
| NCT07085468 | — | P2 | terminated | A Study of LY3549492 in Healthy Weight Adult Participants |
| NCT04758234 | — | P1 | completed | A Study of LY3549492 in Healthy Participants |
Obesity (2)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06143956 | LY900038 | P2 | recruiting | A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight |
| NCT06683508 | — | P2 | completed | A Study to Investigate Weight Management With LY3549492 Compared With Placebo in Adult Participants With Obesity or Overweight |
Type 2 Diabetes (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07073170 | — | P1 | completed | A Study of LY3549492 in Chinese Participants With Type 2 Diabetes Mellitus |
Healthy Male (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06194500 | — | P1 | completed | A Study of Carbon-14-Labeled [14C]-LY3549492 in Healthy Participants |
Diabetes Mellitus, Type 2 (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT05327595 | T2DM | P1 | completed | A Study of LY3549492 in Participants With Type 2 Diabetes Mellitus (T2DM) |
LY3549492 pivotal trial highlights (Phase 2/3/4)
Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.
| Acronym | NCT | Phase | Status | Indication | Enrollment | PubMed |
|---|---|---|---|---|---|---|
| LY900038 | NCT06143956 | P2 | recruiting | Obesity | 1,481 | — |
Terminated and withdrawn LY3549492 trials (1)
Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.
- NCT07085468terminatedA Study of LY3549492 in Healthy Weight Adult Participants
All LY3549492 trials (9)
Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.
| NCT ID | Acronym | Title | Phase | Status | Enrollment | Sponsor | Started |
|---|---|---|---|---|---|---|---|
| NCT06143956 | LY900038 | A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight | P2 | recruiting | 1,481 | Eli Lilly and Company | Nov 2023 |
| NCT07232732 | A Study of LY3549492 in Healthy Participants and Participants With Overweight or Obesity | P1 | active not recruiting | 120 | Eli Lilly and Company | Oct 2025 | |
| NCT06683508 | A Study to Investigate Weight Management With LY3549492 Compared With Placebo in Adult Participants With Obesity or Overweight | P2 | completed | 288 | Eli Lilly and Company | Nov 2024 | |
| NCT06869018 | T2D | A Study of LY3549492 in Japanese Participants With Type 2 Diabetes Mellitus (T2D) and Healthy Japanese Participants | P1 | completed | 92 | Eli Lilly and Company | May 2025 |
| NCT07073170 | A Study of LY3549492 in Chinese Participants With Type 2 Diabetes Mellitus | P1 | completed | 36 | Eli Lilly and Company | Jul 2025 | |
| NCT07085468 | A Study of LY3549492 in Healthy Weight Adult Participants | P2 | terminated | 1 | Eli Lilly and Company | Jul 2025 | |
| NCT05327595 | T2DM | A Study of LY3549492 in Participants With Type 2 Diabetes Mellitus (T2DM) | P1 | completed | 80 | Eli Lilly and Company | May 2022 |
| NCT06194500 | A Study of Carbon-14-Labeled [14C]-LY3549492 in Healthy Participants | P1 | completed | 18 | Eli Lilly and Company | Jan 2024 | |
| NCT04758234 | A Study of LY3549492 in Healthy Participants | P1 | completed | 54 | Eli Lilly and Company | Feb 2021 |
LY3549492 clinical trials: frequently asked questions
- How many LY3549492 clinical trials are there?
- 9 LY3549492 clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 1 is actively recruiting participants. 6 are marked completed.
- Are LY3549492 clinical trials recruiting in 2026?
- Yes — 1 LY3549492 trial is actively recruiting in 2026, with 49 U.S. sites across 22 states. See the recruiting trials and the per-state site list further down this page.
- What conditions is LY3549492 being studied for?
- LY3549492 is being studied for Healthy, Obesity, Overweight, Diabetes Mellitus, Type 2, Type 2 Diabetes Mellitus (T2D) and 2 more. The trials are grouped by indication on this page.
- What phase is LY3549492 in?
- LY3549492 clinical trials span 3 Phase 2, 6 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
- Who sponsors LY3549492 clinical trials?
- The lead sponsor across the most LY3549492 trials is Eli Lilly and Company. Each trial row links to the full study detail page including sponsor information.
Sources and methodology
Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming LY3549492as an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.
Last refreshed .
Related pages on Hipa.ai: