Ixo-vec Clinical Trials (2026): 2 Studies for Neovascular Age-Related Macular Degeneration (nAMD) & Wet AMD

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: .

2 Ixo-vec clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 1 indication (including Neovascular Age-Related Macular Degeneration (nAMD) & Wet AMD) and 595 total planned enrollment. 2 Phase 3 Ixo-vec trials are listed. 1 Ixo-vec clinical trial is actively recruiting at 46 U.S. sites across 15 states. Most recent activity: NCT07482176 (Oct 2031).

Where to Participate: All Ixo-vec Trial Sites in the U.S. (46 sites across 15 states)

Every actively recruiting Ixo-vectrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
AZAdverum Clinical Site 126Phoenix85014NCT07482176Map
AZAdverum Clinical Site 178Phoenix85020NCT07482176Map
AZAdverum Clinical Site 223Phoenix85020NCT07482176Map
AZAdverum Clinical Site 229Scottsdale85255NCT07482176Map
ARAdverum Clinical Site 198Springdale72764NCT07482176Map
CAAdverum Clinical Site 109Bakersfield93309NCT07482176Map
CAAdverum Clinical Site 100Beverly Hills90211NCT07482176Map
CAAdverum Clinical Site 201Campbell95008NCT07482176Map
CAAdverum Clinical Site 172Encino91436NCT07482176Map
CAAdverum Clinical Site 169Fullerton92835NCT07482176Map
CAAdverum Clinical Site 224Huntington Beach92647NCT07482176Map
CAAdverum Clinical Site 215Redlands92374NCT07482176Map
CAAdverum Clinical Site 140Sacramento95825NCT07482176Map
CAAdverum Clinical Site 212Sacramento95841NCT07482176Map
CAAdverum Clinical Site 202Torrance90503NCT07482176Map
CAAdverum Clinical Site 189Walnut Creek94598NCT07482176Map
COAdverum Clinical Site 116Denver80207NCT07482176Map
CTAdverum Clinical Site 165Waterford06385NCT07482176Map
FLAdverum Clinical Site 124Deerfield Beach33064NCT07482176Map
FLAdverum Clinical Site 184Deerfield Beach33064NCT07482176Map
FLAdverum Clinical Site 176Fort Lauderdale33308NCT07482176Map
FLAdverum Clinical Site 221Fort Myers33912NCT07482176Map
FLAdverum Clinical Site 214Lakeland33805NCT07482176Map
FLAdverum Clinical Site 213Orlando32806NCT07482176Map
FLAdverum Clinical Site 183South Miami33143NCT07482176Map
GAAdverum Clinical Site 182Augusta30909NCT07482176Map
INAdverum Clinical Site 195Carmel46032NCT07482176Map
MDAdverum Clinical Site 204Hagerstown21740NCT07482176Map
MSAdverum Clinical Site 216Jackson39202NCT07482176Map
NYAdverum Clinical Site 225Liverpool13088NCT07482176Map
NCAdverum Clinical Site 196Asheville28803NCT07482176Map
NCAdverum Clinical Site 211Greensboro27401NCT07482176Map
NCAdverum Clinical Site 219Greensboro27401NCT07482176Map
NCAdverum Clinical Site 220Hickory28602NCT07482176Map
NCAdverum Clinical Site 209Wake Forest27587NCT07482176Map
SCAdverum Clinical Site 241Bluffton29910NCT07482176Map
SCAdverum Clinical Site 222Ladson29456NCT07482176Map
TXAdverum Clinical Site 127Austin78705NCT07482176Map
TXAdverum Clinical Site 107Conroe77384NCT07482176Map
TXAdverum Clinical Site 194Dallas75231NCT07482176Map
TXAdverum Clinical Site 162McAllen78503NCT07482176Map
TXAdverum Clinical Site 232San Marcos78666NCT07482176Map
TXAdverum Clinical Site 228Schertz78154NCT07482176Map
TXAdverum Clinical Site 231The Woodlands77384NCT07482176Map
TXAdverum Clinical Site 237Tyler75703NCT07482176Map
VAAdverum Clinical Site 199Lynchburg24502NCT07482176Map

Ixo-vec clinical trials at a glance: phase × recruitment status

Phaserecruitingactive not recruitingTotal
P3112

Recruiting Ixo-vec clinical trials (1)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT07482176AQUARIUSEfficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)P3Neovascular Age-Related Macular Degeneration (nAMD)284Mar 2026

Ixo-vec pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

AcronymNCTPhaseStatusIndicationEnrollmentPubMed
AQUARIUSNCT07482176P3recruitingNeovascular Age-Related Macular Degeneration (nAMD)284
ARTEMISNCT06856577P3active not recruitingNeovascular Age-Related Macular Degeneration (nAMD)311

All Ixo-vec trials (2)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT07482176AQUARIUSEfficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)P3recruiting284Adverum Biotechnologies, Inc.Mar 2026
NCT06856577ARTEMISEfficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular DegenerationP3active not recruiting311Adverum Biotechnologies, Inc.Feb 2025

Ixo-vec clinical trials: frequently asked questions

How many Ixo-vec clinical trials are there?
2 Ixo-vec clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 1 is actively recruiting participants.
Are Ixo-vec clinical trials recruiting in 2026?
Yes — 1 Ixo-vec trial is actively recruiting in 2026, with 46 U.S. sites across 15 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Ixo-vec being studied for?
Ixo-vec is being studied for Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD. The trials are grouped by indication on this page.
What phase is Ixo-vec in?
Ixo-vec clinical trials span 2 Phase 3. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Ixo-vec clinical trials?
The lead sponsor across the most Ixo-vec trials is Adverum Biotechnologies, Inc.. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Ixo-vecas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

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