Ixo-vec Clinical Trials (2026): 2 Studies for Neovascular Age-Related Macular Degeneration (nAMD) & Wet AMD
Hipa.ai Research · Source: ClinicalTrials.gov / AACT
Synced daily from ClinicalTrials.gov via AACT. Last sync: .
2 Ixo-vec clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 1 indication (including Neovascular Age-Related Macular Degeneration (nAMD) & Wet AMD) and 595 total planned enrollment. 2 Phase 3 Ixo-vec trials are listed. 1 Ixo-vec clinical trial is actively recruiting at 46 U.S. sites across 15 states. Most recent activity: NCT07482176 (Oct 2031).
Where to Participate: All Ixo-vec Trial Sites in the U.S. (46 sites across 15 states)
Every actively recruiting Ixo-vectrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.
| State | Facility | City | Trial | Map |
|---|---|---|---|---|
| AZ | Adverum Clinical Site 126 | Phoenix85014 | NCT07482176 | Map |
| AZ | Adverum Clinical Site 178 | Phoenix85020 | NCT07482176 | Map |
| AZ | Adverum Clinical Site 223 | Phoenix85020 | NCT07482176 | Map |
| AZ | Adverum Clinical Site 229 | Scottsdale85255 | NCT07482176 | Map |
| AR | Adverum Clinical Site 198 | Springdale72764 | NCT07482176 | Map |
| CA | Adverum Clinical Site 109 | Bakersfield93309 | NCT07482176 | Map |
| CA | Adverum Clinical Site 100 | Beverly Hills90211 | NCT07482176 | Map |
| CA | Adverum Clinical Site 201 | Campbell95008 | NCT07482176 | Map |
| CA | Adverum Clinical Site 172 | Encino91436 | NCT07482176 | Map |
| CA | Adverum Clinical Site 169 | Fullerton92835 | NCT07482176 | Map |
| CA | Adverum Clinical Site 224 | Huntington Beach92647 | NCT07482176 | Map |
| CA | Adverum Clinical Site 215 | Redlands92374 | NCT07482176 | Map |
| CA | Adverum Clinical Site 140 | Sacramento95825 | NCT07482176 | Map |
| CA | Adverum Clinical Site 212 | Sacramento95841 | NCT07482176 | Map |
| CA | Adverum Clinical Site 202 | Torrance90503 | NCT07482176 | Map |
| CA | Adverum Clinical Site 189 | Walnut Creek94598 | NCT07482176 | Map |
| CO | Adverum Clinical Site 116 | Denver80207 | NCT07482176 | Map |
| CT | Adverum Clinical Site 165 | Waterford06385 | NCT07482176 | Map |
| FL | Adverum Clinical Site 124 | Deerfield Beach33064 | NCT07482176 | Map |
| FL | Adverum Clinical Site 184 | Deerfield Beach33064 | NCT07482176 | Map |
| FL | Adverum Clinical Site 176 | Fort Lauderdale33308 | NCT07482176 | Map |
| FL | Adverum Clinical Site 221 | Fort Myers33912 | NCT07482176 | Map |
| FL | Adverum Clinical Site 214 | Lakeland33805 | NCT07482176 | Map |
| FL | Adverum Clinical Site 213 | Orlando32806 | NCT07482176 | Map |
| FL | Adverum Clinical Site 183 | South Miami33143 | NCT07482176 | Map |
| GA | Adverum Clinical Site 182 | Augusta30909 | NCT07482176 | Map |
| IN | Adverum Clinical Site 195 | Carmel46032 | NCT07482176 | Map |
| MD | Adverum Clinical Site 204 | Hagerstown21740 | NCT07482176 | Map |
| MS | Adverum Clinical Site 216 | Jackson39202 | NCT07482176 | Map |
| NY | Adverum Clinical Site 225 | Liverpool13088 | NCT07482176 | Map |
| NC | Adverum Clinical Site 196 | Asheville28803 | NCT07482176 | Map |
| NC | Adverum Clinical Site 211 | Greensboro27401 | NCT07482176 | Map |
| NC | Adverum Clinical Site 219 | Greensboro27401 | NCT07482176 | Map |
| NC | Adverum Clinical Site 220 | Hickory28602 | NCT07482176 | Map |
| NC | Adverum Clinical Site 209 | Wake Forest27587 | NCT07482176 | Map |
| SC | Adverum Clinical Site 241 | Bluffton29910 | NCT07482176 | Map |
| SC | Adverum Clinical Site 222 | Ladson29456 | NCT07482176 | Map |
| TX | Adverum Clinical Site 127 | Austin78705 | NCT07482176 | Map |
| TX | Adverum Clinical Site 107 | Conroe77384 | NCT07482176 | Map |
| TX | Adverum Clinical Site 194 | Dallas75231 | NCT07482176 | Map |
| TX | Adverum Clinical Site 162 | McAllen78503 | NCT07482176 | Map |
| TX | Adverum Clinical Site 232 | San Marcos78666 | NCT07482176 | Map |
| TX | Adverum Clinical Site 228 | Schertz78154 | NCT07482176 | Map |
| TX | Adverum Clinical Site 231 | The Woodlands77384 | NCT07482176 | Map |
| TX | Adverum Clinical Site 237 | Tyler75703 | NCT07482176 | Map |
| VA | Adverum Clinical Site 199 | Lynchburg24502 | NCT07482176 | Map |
Ixo-vec clinical trials at a glance: phase × recruitment status
| Phase | recruiting | active not recruiting | Total |
|---|---|---|---|
| P3 | 1 | 1 | 2 |
Recruiting Ixo-vec clinical trials (1)
Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).
| NCT ID | Title | Phase | Indication | Enrollment | Started |
|---|---|---|---|---|---|
| NCT07482176 | AQUARIUSEfficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS) | P3 | Neovascular Age-Related Macular Degeneration (nAMD) | 284 | Mar 2026 |
Ixo-vec pivotal trial highlights (Phase 2/3/4)
Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.
| Acronym | NCT | Phase | Status | Indication | Enrollment | PubMed |
|---|---|---|---|---|---|---|
| AQUARIUS | NCT07482176 | P3 | recruiting | Neovascular Age-Related Macular Degeneration (nAMD) | 284 | — |
| ARTEMIS | NCT06856577 | P3 | active not recruiting | Neovascular Age-Related Macular Degeneration (nAMD) | 311 | — |
All Ixo-vec trials (2)
Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.
| NCT ID | Acronym | Title | Phase | Status | Enrollment | Sponsor | Started |
|---|---|---|---|---|---|---|---|
| NCT07482176 | AQUARIUS | Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS) | P3 | recruiting | 284 | Adverum Biotechnologies, Inc. | Mar 2026 |
| NCT06856577 | ARTEMIS | Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular Degeneration | P3 | active not recruiting | 311 | Adverum Biotechnologies, Inc. | Feb 2025 |
Ixo-vec clinical trials: frequently asked questions
- How many Ixo-vec clinical trials are there?
- 2 Ixo-vec clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 1 is actively recruiting participants.
- Are Ixo-vec clinical trials recruiting in 2026?
- Yes — 1 Ixo-vec trial is actively recruiting in 2026, with 46 U.S. sites across 15 states. See the recruiting trials and the per-state site list further down this page.
- What conditions is Ixo-vec being studied for?
- Ixo-vec is being studied for Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD. The trials are grouped by indication on this page.
- What phase is Ixo-vec in?
- Ixo-vec clinical trials span 2 Phase 3. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
- Who sponsors Ixo-vec clinical trials?
- The lead sponsor across the most Ixo-vec trials is Adverum Biotechnologies, Inc.. Each trial row links to the full study detail page including sponsor information.
Sources and methodology
Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Ixo-vecas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.
Last refreshed .
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