Iberdomide Clinical Trials (2026): 35 Studies for Multiple Myeloma & Refractory Multiple Myeloma

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: .

35 Iberdomide clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 14 indications (including Multiple Myeloma & Refractory Multiple Myeloma) and 5,185 total planned enrollment. 4 Phase 3 Iberdomide trials and 12 Phase 2 are listed. 20 Iberdomide clinical trials are actively recruiting at 165 U.S. sites across 33 states. Most recent activity: NCT06896916 (Mar 2036).

Where to Participate: All Iberdomide Trial Sites in the U.S. (165 sites across 33 states)

Every actively recruiting Iberdomidetrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
ALUniversity of Alabama at BirminghamBirmingham35294-3300NCT06121843Map
AZMayo Clinic Hospital in ArizonaPhoenix85054NCT06465316Map
AZMayo Clinic in Arizona - PhoenixPhoenix85054NCT06121843Map
CABeverly Hills Cancer Center /ID# 266921Beverly Hills90211NCT06896916Map
CACity of Hope Comprehensive Cancer CenterDuarte91010NCT06121843Map
CAUCSF/Hematology, Blood & Marrow Transplant, And Cellular Therapy (HBC) ProgramSan Francisco94143NCT05169515Map
CAUniversity of Calfornia, San FranciscoSan Francisco94143NCT06348108Map
CORocky Mountain Cancer CentersAurora80012-5405NCT05827016Map
COUniversity of ColoradoAurora80045NCT05169515Map
COColorado Blood Cancer Institute /ID# 273751Denver80218NCT06896916Map
CTSmilow Cancer Hospital-Derby Care CenterDerby06418NCT06465316Map
CTSmilow Cancer Hospital Care Center - GuilfordGuilford06437NCT06465316Map
CTYale UniversityNew Haven06520NCT06465316Map
CTYale-New Haven Hospital North Haven Medical CenterNorth Haven06473NCT06465316Map
DCLombardi Comprehensive Cancer CenterWashington D.C.20007NCT05199311Map
FLSylvester Comprehensive Cancer Center - The Lennar Foundation Medical CenterCoral Gables33146NCT06215118Map
FLUniversity of Miami Hospital and Clinics Deerfield BeachDeerfield Beach33442NCT06215118Map
FLSylvester Comprehensive Cancer Center- DoralDoral33166NCT06215118Map
FLMayo Clinic FloridaJacksonville32224NCT05827016Map
FLMayo Clinic in FloridaJacksonville32224NCT06121843Map
FLMayo Clinic in FloridaJacksonville32224-9980NCT06465316Map
FLSylvester Comprehensive Cancer CenterMiami33136NCT06215118Map
FLSylvester Comprehensive Cancer Center KendallMiami33176NCT06215118Map
FLUniversity of MiamiMiami33136NCT05896228Map
FLUniversity of Miami Hospital and ClinicsMiami33136NCT06215118Map
FLSylvester Comprehensive Cancer Center PlantationPlantation33324NCT06215118Map
FLH. Lee Moffitt Cancer Center & Research InstituteTampa33612-9416NCT05827016Map
FLMoffitt Cancer CenterTampa33612NCT05169515Map
FLTampa General HospitalTampa33606NCT05827016Map
FLCleveland ClinicWeston33331-3609NCT05827016Map
GAUniversity Cancer Blood CtrAthens30607-1465NCT05827016Map
GAEmory University HospitalAtlanta30322NCT06215118Map
GAEmory University Hospital MidtownAtlanta30308NCT06215118Map
GAEmory University Hospital/Winship Cancer InstituteAtlanta30322NCT04776395Map
GANorthside HospitalAtlanta30342NCT06121843Map
GAThe Winship Cancer Institute of Emory UniversityAtlanta30322-1013NCT05827016Map
GAWinship Cancer InstituteAtlanta30322NCT06215118Map
GAAugusta University - Georgia Cancer CenterAugusta30912NCT05827016Map
ILThe University of ChicagoChicago60637NCT05169515Map
ILThe University of Chicago Medical Center - Duchossois Center for Advanced MedicineChicago60637-1426NCT05827016Map
INIndiana CTSI Clinical Research Center (ICRC)Indianapolis46202NCT06215118Map
INIndiana University Health University HospitalIndianapolis46202NCT06215118Map
INIndiana University Melvin and Bren Simon Comprehensive Cancer Center (IUSCCC)Indianapolis46202NCT06215118Map
IAMary Greeley Medical CenterAmes50010NCT06232044Map
IAMcFarland Clinic - AmesAmes50010NCT06232044Map
IAMcFarland Clinic - Trinity Cancer CenterFort Dodge50501NCT06232044Map
IAMcFarland Clinic - MarshalltownMarshalltown50158NCT06232044Map
KSUniversity of Kansas Cancer CenterKansas City66160NCT06465316Map
KSUniversity of Kansas Cancer Center-Overland ParkOverland Park66210NCT06465316Map
KSUniversity of Kansas Cancer Center - The Richard and Annette Bloch Cancer Care PavilionWestwood66205-2003NCT05827016Map
KSUniversity of Kansas Hospital-Westwood Cancer CenterWestwood66205NCT06465316Map
MDUniversity of MarylandBaltimore21201NCT06215118Map
MDMaryland Oncology Hematology, PA- ClintonClinton20735-4230NCT05827016Map
MABeth Israel Deaconess Medical CenterBoston02215NCT06121843Map
MABeth Israel Deaconess Medical CenterBoston02215NCT06518551Map
MABrigham and Women's HospitalBoston02115NCT06215118Map
MADana Farber Cancer InstituteBoston02215NCT06518551Map
MADana-Farber Cancer InstituteBoston02215NCT06121843Map
MADana-Farber Cancer InstituteBoston02215NCT06215118Map
MADana-Farber Cancer InstituteBoston02215NCT06232044Map
MATufts Medical CenterBoston02111NCT06232044Map
MADana-Farber Cancer Institute - Chestnut HillNewton02459NCT06215118Map
MAUMass Memorial Medical CenterWorcester01655NCT05827016Map
MAUniversity of Massachusetts Chan Medical SchoolWorcester01655NCT06215118Map
MIUniversity of Michigan - Rogel Cancer CenterAnn Arbor48109-5000NCT05827016Map
MIHenry Ford Health System - The Henry Ford Cancer Institute (HFCI) - DetroitDetroit48202-2610NCT05827016Map
MIKarmanos Cancer InstituteDetroit48201NCT06107738Map
MICancer & Hematology Centers of Western Michigan (CHCWM)Grand Rapids49503NCT05827016Map
MIKCI at McLaren Greater LansingLansing48910NCT06107738Map
MNMayo Clinic Cancer Center (MCCC) - RochesterRochester55905NCT05827016Map
MNMayo Clinic in RochesterRochester55905NCT06465316Map
MNMayo Clinic in RochesterRochester55905NCT06785415Map
MNMayo Clinic in Rochester, MinnesotaRochester55905NCT06121843Map
MNCoborn Cancer Center at Saint Cloud HospitalSaint Cloud56303NCT06232044Map
MSHattiesburg Clinic - Hematology & OncologyHattiesburg39401NCT05827016Map
MOWashington University /ID# 266972St Louis63110NCT06896916Map
NEMethodist HospitalOmaha68114NCT06215118Map
NEOncology Hematology West P.C. dba Nebraska Cancer - MethodistOmaha68114NCT06215118Map
NEOncology Hematology West P.C. dba Nebraska Cancer SpecialistsOmaha68130NCT06215118Map
NEUniversity Of Nebraska Medical CenterOmaha68198NCT06121843Map
NHDartmouth Hitchcock Medical CenterLebanon03756NCT06215118Map
NJMSK Basking RidgeBasking Ridge07920NCT06215118Map
NJJohn Theurer Cancer CenterHackensack07601NCT05199311Map
NJJohn Theurer Cancer Center at Hackensack University Medical CenterHackensack07601NCT06121843Map
NJMemorial Sloan Kettering MonmouthMiddletown07748NCT06232044Map
NJMSK MonmouthMiddletown07748NCT06215118Map
NJMemorial Sloan Kettering BergenMontvale07645NCT06232044Map
NJMSK BergenMontvale07645NCT06215118Map
NJMorristown Medical CenterMorristown07960NCT05827016Map
NJRutgers Cancer Institute of New Jersey /ID# 266833New Brunswick08901NCT06896916Map
NYRoswell Park Cancer InstituteBuffalo14263NCT06121843Map
NYMemorial Sloan Kettering CommackCommack11725NCT06232044Map
NYMSK CommackCommack11725NCT06215118Map
NYMemorial Sloan Kettering WestchesterHarrison10604NCT06232044Map
NYMSK WestchesterHarrison10604NCT06215118Map
NYMemorial Sloan Kettering Cancer Center - Investigational Drug Service PharmacyLong Island City11101NCT06215118Map
NYPerlmutter Cancer Center at NYU Langone Hematology Oncology Associates-MineolaMineola11501NCT05827016Map
NYColumbia University Medical Center - Herbert Irving Pavilion LocationNew York10032-3729NCT05827016Map
NYLaura and Isaac Perlmutter Cancer CenterNew York10016NCT06121843Map
NYMemorial Sloan Kettering Cancer CenterNew York10065NCT06121843Map
NYMemorial Sloan Kettering Cancer CenterNew York10065NCT06232044Map
NYMemorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street).New York10021NCT06215118Map
NYMemorial Sloan Kettering Cancer Center - Main CampusNew York10065NCT06215118Map
NYMemorial Sloan Kettering Cancer Center - New York - York Avenue /ID# 270282New York10065NCT06896916Map
NYNYU Langone HealthNew York10016-6402NCT05827016Map
NYMSK NassauUniondale11553NCT06215118Map
NYClinical Research AllianceWestbury11590NCT05827016Map
NCLevine Cancer InstituteCharlotte28204NCT05827016Map
NCLevine Cancer InstituteCharlotte28204NCT05169515Map
NCNovant Health Cancer Institute - ElizabethCharlotte28803-2493NCT05827016Map
NCDuke University HospitalDurham27705-3976NCT05827016Map
NCUniversity Of North Carolina Health Care - Hillsborough Campus /ID# 278230Hillsborough27278NCT06896916Map
NCNovant Health Cancer Institute Hematology - ForsythWinston-Salem27103NCT05827016Map
NCWake Forest University Baptist Medical Center (WFUBMC) - Comprehensive Cancer CenterWinston-Salem27157NCT05827016Map
OHOhioHealth O'Bleness HospitalAthens45701NCT06232044Map
OHOncology Hematology Care, Inc. - Cincinnati - Galbraith RdCincinnati45236-2725NCT05827016Map
OHCleveland ClinicCleveland44195NCT05827016Map
OHCleveland Clinic - Fairview Hospital - Cancer Center (Moll Cancer Center)Cleveland44111NCT05827016Map
OHColumbus Oncology and Hematology Associates IncColumbus43214NCT06232044Map
OHDoctors HospitalColumbus43228NCT06232044Map
OHGrant Medical CenterColumbus43215NCT06232044Map
OHOhio State University Comprehensive Cancer CenterColumbus43210NCT06465316Map
OHRiverside Methodist HospitalColumbus43214NCT06232044Map
OHDelaware Health Center-Grady Cancer CenterDelaware43015NCT06232044Map
OHGrady Memorial HospitalDelaware43015NCT06232044Map
OHColumbus Oncology and Hematology AssociatesDublin43016NCT06232044Map
OHDublin Methodist HospitalDublin43016NCT06232044Map
OHMidwest Oncology Associates - Kansas CityKansas64132NCT05827016Map
OHOhioHealth Mansfield HospitalMansfield44903NCT06232044Map
OHOhioHealth Marion General HospitalMarion43302NCT06232044Map
OHCleveland Clinic - Hillcrest Hospital - Hillcrest Cancer CenterMayfield Heights44124NCT05827016Map
OHOhioHealth Pickerington Methodist HospitalPickerington43147NCT06232044Map
OHOhioHealth Westerville Medical Campus/Westerville Cancer CenterWesterville43082NCT06232044Map
OHWooster Milltown Specialty and Surgery CenterWooster44691NCT05827016Map
OKUniversity of Oklahoma Health Sciences CenterOklahoma City73104NCT06232044Map
OKUniversity of Oklahoma Health Sciences CenterOklahoma City73104NCT06465316Map
ORWillamette Valley Cancer InstituteEugene97401NCT05827016Map
PAFox Chase Cancer Center - Jeanes CampusPhiladelphia19111-2433NCT05827016Map
PAThomas Jefferson University HospitalPhiladelphia19107NCT05827016Map
PAUniversity of Pittsburgh - Hillman Cancer CenterPittsburgh15232NCT05827016Map
TNWest Cancer CenterGermantown38138-1762NCT05827016Map
TNTennessee OncologyNashville37203-1625NCT05827016Map
TNTennessee OncologyNashville37203NCT06121843Map
TNVanderbilt University/Ingram Cancer CenterNashville37232NCT06232044Map
TXTexas Oncology - Baylor Charles A. Sammons Cancer CenterDallas75246NCT05827016Map
TXUT Southwestern-Harold C. Simmons Cancer CenterDallas75390-0001NCT05827016Map
TXUniversity of Texas MD Anderson Cancer CenterHouston77030-4000NCT05827016Map
TXUniversity of Texas MD Anderson Cancer CenterHouston77030NCT06121843Map
TXUT MD Anderson Cancer CenterHouston77030NCT05169515Map
UTHuntsman Cancer Institute/University of UtahSalt Lake City84112NCT06232044Map
VAVCU Massey Comprehensive Cancer CenterRichmond23298NCT06465316Map
WAFred Hutchinson Cancer CenterSeattle98109NCT06215118Map
WASwedish Medical Center - Seattle /ID# 268052Seattle98104NCT06896916Map
WAUniversity of WashingtonSeattle98195NCT06215118Map
WISaint Vincent Hospital Cancer Center at Saint Mary'sGreen Bay54303NCT06232044Map
WISaint Vincent Hospital Cancer Center Green BayGreen Bay54301NCT06232044Map
WIMedical College of WisconsinMilwaukee53226NCT06215118Map
WIMedical College of WisconsinMilwaukee53226NCT06232044Map
WIProHealth D N Greenwald CenterMukwonago53149NCT06232044Map
WIProHealth Oconomowoc Memorial HospitalOconomowoc53066NCT06232044Map
WISaint Vincent Hospital Cancer Center at SheboyganSheboygan53081NCT06232044Map
WISheboygan Physicians GroupSheboygan53081NCT06232044Map
WISaint Vincent Hospital Cancer Center at Sturgeon BaySturgeon Bay54235-1495NCT06232044Map
WIProHealth Waukesha Memorial HospitalWaukesha53188NCT06232044Map
WIUW Cancer Center at ProHealth CareWaukesha53188NCT06232044Map

Iberdomide clinical trials at a glance: phase × recruitment status

Phaserecruitingactive not recruitingcompletedterminatedsuspendednot yet recruitingavailableTotal
Early P111
P16219
P1/P25218
P256112
P32114
N/A11

Recruiting Iberdomide clinical trials (20)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT06896916IVStudy of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple MyelomaP1Multiple Myeloma135Aug 2025
NCT05827016A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple MyelomaP3Multiple Myeloma1,216Jun 2023
NCT06518551Elotuzumab + Iberdomide + Dexamethasone Post Ide-Cel in RRMMP1/P2Myeloma49Nov 2024
NCT06762769MODIFYIsatuximab and Iberdomide as Immunotherapy for High Risk in Smouldering MyelomaP2Smouldering Myeloma63Jun 2025
NCT06785415Elotuzumab, Daratumumab, Iberdomide, and Dexamethasone for the Treatment of Relapsed Multiple MyelomaP1/P2Recurrent Multiple Myeloma37Mar 2025
NCT05272826BOREALISStudy of Iberdomide, Bortezomib, Dexamethasone With Isatuximab Added on Demand for ND-NTE MM PatientsP2Multiple Myeloma75Dec 2024
NCT05896228Iber-KDdIberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With Relapsed/Refractory Multiple MyelomaP2Refractory Multiple Myeloma30Feb 2024
NCT06232044Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple MyelomaP1/P2Recurrent Multiple Myeloma88Apr 2025
NCT07437963Testing the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten WorseP1/P2Recurrent Ganglioneuroblastoma76Jul 2026
NCT05169515A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin LymphomaP1Non-Hodgkin Lymphoma121Oct 2022
NCT04776395Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple MyelomaP2Smoldering Plasma Cell Myeloma68Jul 2021
NCT06348108Talquetamab in Combination With Iberdomide and Dexamethasone for Relapsed or Refractory Multiple MyelomaP1Multiple Myeloma32Jul 2025
NCT06216158Iberdomide vs. Iberdomide Plus Isatuximab Maintenance Therapy Post ASCT in Newly Diagnosed Multiple MyelomaP3Multiple Myeloma411Apr 2024
NCT05558319GEM21menos65NDMM Patients Candidates for ASCT Comparing Extended VRD Plus vs. Isa-VRD vs. Isa-V-IberdomideP3Newly Diagnosed Multiple Myeloma480Oct 2022
NCT06121843BMS-986393A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple MyelomaP1Multiple Myeloma147Feb 2024
NCT05583617PLYCOMA Study Evaluating the Safety and Efficacy of Multiple Treatments in Participants With Multiple MyelomaP1/P2Multiple Myeloma200Nov 2023
NCT06215118PF-06863135A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and Iberdomide in Patients With Relapsed or Refractory Multiple Myeloma (MagnetisMM-30)P1Multiple Myeloma87Feb 2024
NCT06465316TECVAYLITesting Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple MyelomaP1Recurrent Multiple Myeloma26Dec 2024
NCT06107738IBEXIberdomide and Daratumumab As Maintenance Therapy After an Autologous Stem Cell Transplant for Multiple MyelomaP2Multiple Myeloma60Dec 2023
NCT05199311CC-220Carfilzomib, Iberdomide (CC-220) and Dexamethasone (KID) in Transplant Eligible Multiple MyelomaP1/P2Multiple Myeloma66May 2022

Iberdomide clinical trials by indication

Multiple Myeloma (20)

NCTAcronymPhaseStatusTitle
NCT06896916IVP1recruitingStudy of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma
NCT05827016P3recruitingA Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma
NCT04975997EXCALIBER-RRMMP3active not recruitingOpen-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
NCT05272826BOREALISP2recruitingStudy of Iberdomide, Bortezomib, Dexamethasone With Isatuximab Added on Demand for ND-NTE MM Patients
NCT05177536P2active not recruitingIberdomide Maintenance Therapy in Patients With Multiple Myeloma
NCT05527340P2active not recruitingIberdomide-dexamethasone Alone or in Combination With Standard MM Treatment Regimens in Transplant Ineligible Newly Diagnosed Patients.
NCT06348108P1recruitingTalquetamab in Combination With Iberdomide and Dexamethasone for Relapsed or Refractory Multiple Myeloma
NCT06216158P3recruitingIberdomide vs. Iberdomide Plus Isatuximab Maintenance Therapy Post ASCT in Newly Diagnosed Multiple Myeloma
+ 12 more, see All trials below.

Recurrent Multiple Myeloma (3)

NCTAcronymPhaseStatusTitle
NCT06785415P1/P2recruitingElotuzumab, Daratumumab, Iberdomide, and Dexamethasone for the Treatment of Relapsed Multiple Myeloma
NCT06232044P1/P2recruitingTesting the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple Myeloma
NCT06465316TECVAYLIP1recruitingTesting Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple Myeloma

Recurrent Ganglioneuroblastoma (1)

NCTAcronymPhaseStatusTitle
NCT07437963P1/P2not yet recruitingTesting the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten Worse

Smouldering Myeloma (1)

NCTAcronymPhaseStatusTitle
NCT06762769MODIFYP2recruitingIsatuximab and Iberdomide as Immunotherapy for High Risk in Smouldering Myeloma

Myeloma (1)

NCTAcronymPhaseStatusTitle
NCT06518551P1/P2recruitingElotuzumab + Iberdomide + Dexamethasone Post Ide-Cel in RRMM

Refractory Multiple Myeloma (1)

NCTAcronymPhaseStatusTitle
NCT05896228Iber-KDdP2recruitingIberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With Relapsed/Refractory Multiple Myeloma

Healthy Volunteers (1)

NCTAcronymPhaseStatusTitle
NCT05899738CC-220P1completedA Study to Compare the Relative Bioavailability of Two Iberdomide (CC-220) Formulations and to Assess The Effect Of Food on the Drug Levels of Iberdomide in Healthy Adult Participants

Newly Diagnosed Multiple Myeloma (1)

NCTAcronymPhaseStatusTitle
NCT05558319GEM21menos65P3not yet recruitingNDMM Patients Candidates for ASCT Comparing Extended VRD Plus vs. Isa-VRD vs. Isa-V-Iberdomide

Non-Hodgkin Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT05169515P1recruitingA Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma

Plasma Cell Myeloma (1)

NCTAcronymPhaseStatusTitle
NCT05392946P1/P2active not recruitingIberdomide, Daratumumab, Bortezomib, and Dexamethasone for Treatment of Newly Diagnosed Multiple Myeloma, IDEAL Study

Multiple Myeloma at First Relapse (1)

NCTAcronymPhaseStatusTitle
NCT04998786I2D IFM2021_03P2active not recruitingA Multi-center Open-label Phase 2 Study of Ixazomib, Iberdomide and Dexamethasone in Elderly Patients With Multiple Myeloma at First Relapse."

Renal Insufficiency (1)

NCTAcronymPhaseStatusTitle
NCT04933747CC-220P1completedStudy to Evaluate Safety and Tolerability of Iberdomide (CC-220) in Participants With Kidney Impairment Compared to Participants With Normal Kidney Function

Smoldering Plasma Cell Myeloma (1)

NCTAcronymPhaseStatusTitle
NCT04776395P2recruitingIberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma

Other (1)

NCTAcronymPhaseStatusTitle
NCT07434960N/AavailableExpanded Access for Iberdomide

Iberdomide pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

AcronymNCTPhaseStatusIndicationEnrollmentPubMed
EXCALIBER-RRMMNCT04975997P3active not recruitingMultiple Myeloma939
GEM21menos65NCT05558319P3not yet recruitingNewly Diagnosed Multiple Myeloma480
MODIFYNCT06762769P2recruitingSmouldering Myeloma63
BOREALISNCT05272826P2recruitingMultiple Myeloma75
Iber-KDdNCT05896228P2recruitingRefractory Multiple Myeloma30
I2D IFM2021_03NCT04998786P2active not recruitingMultiple Myeloma at First Relapse75
ICONNCT04392037P2active not recruitingMultiple Myeloma60
AHCTNCT05354557P2active not recruitingMultiple Myeloma16
IBEXNCT06107738P2recruitingMultiple Myeloma60

Terminated and withdrawn Iberdomide trials (2)

Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.

All Iberdomide trials (35)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT06896916IVStudy of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple MyelomaP1recruiting135AbbVieAug 2025
NCT05827016A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple MyelomaP3recruiting1,216Bristol-Myers SquibbJun 2023
NCT06518551Elotuzumab + Iberdomide + Dexamethasone Post Ide-Cel in RRMMP1/P2recruiting49Omar Nadeem, MDNov 2024
NCT06762769MODIFYIsatuximab and Iberdomide as Immunotherapy for High Risk in Smouldering MyelomaP2recruiting63University College, LondonJun 2025
NCT04975997EXCALIBER-RRMMOpen-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)P3active not recruiting939CelgeneJun 2022
NCT06785415Elotuzumab, Daratumumab, Iberdomide, and Dexamethasone for the Treatment of Relapsed Multiple MyelomaP1/P2recruiting37Mayo ClinicMar 2025
NCT05272826BOREALISStudy of Iberdomide, Bortezomib, Dexamethasone With Isatuximab Added on Demand for ND-NTE MM PatientsP2recruiting75Canadian Myeloma Research GroupDec 2024
NCT05896228Iber-KDdIberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With Relapsed/Refractory Multiple MyelomaP2recruiting30Benjamin T Diamond, MDFeb 2024
NCT05177536Iberdomide Maintenance Therapy in Patients With Multiple MyelomaP2active not recruiting40University of NebraskaJun 2022
NCT06232044Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple MyelomaP1/P2recruiting88Alliance for Clinical Trials in OncologyApr 2025
NCT04998786I2D IFM2021_03A Multi-center Open-label Phase 2 Study of Ixazomib, Iberdomide and Dexamethasone in Elderly Patients With Multiple Myeloma at First Relapse."P2active not recruiting75Nantes University HospitalDec 2021
NCT05527340Iberdomide-dexamethasone Alone or in Combination With Standard MM Treatment Regimens in Transplant Ineligible Newly Diagnosed Patients.P2active not recruiting140PETHEMA FoundationDec 2022
NCT07437963Testing the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten WorseP1/P2not yet recruiting76National Cancer Institute (NCI)Jul 2026
NCT05169515A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin LymphomaP1recruiting121Hoffmann-La RocheOct 2022
NCT04776395Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple MyelomaP2recruiting68Emory UniversityJul 2021
NCT06348108Talquetamab in Combination With Iberdomide and Dexamethasone for Relapsed or Refractory Multiple MyelomaP1recruiting32Alfred Chung, MDJul 2025
NCT06216158Iberdomide vs. Iberdomide Plus Isatuximab Maintenance Therapy Post ASCT in Newly Diagnosed Multiple MyelomaP3recruiting411University of Heidelberg Medical CenterApr 2024
NCT05558319GEM21menos65NDMM Patients Candidates for ASCT Comparing Extended VRD Plus vs. Isa-VRD vs. Isa-V-IberdomideP3not yet recruiting480PETHEMA FoundationOct 2022
NCT05392946Iberdomide, Daratumumab, Bortezomib, and Dexamethasone for Treatment of Newly Diagnosed Multiple Myeloma, IDEAL StudyP1/P2active not recruiting49Mayo ClinicAug 2022
NCT05434689COMMANDERCOMbination Regimens in MM Post AHCT to elimiNate MRD Utilizing IbERdomideP1/P2active not recruiting80University of Alabama at BirminghamJan 2023
NCT06121843BMS-986393A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple MyelomaP1recruiting147Juno Therapeutics, Inc., a Bristol-Myers Squibb CompanyFeb 2024
NCT05583617PLYCOMA Study Evaluating the Safety and Efficacy of Multiple Treatments in Participants With Multiple MyelomaP1/P2recruiting200Hoffmann-La RocheNov 2023
NCT06215118PF-06863135A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and Iberdomide in Patients With Relapsed or Refractory Multiple Myeloma (MagnetisMM-30)P1recruiting87PfizerFeb 2024
NCT04564703Iberdomide (Cc220) Maintenance After Asct in Newly Diagnosed MM PatientsP2active not recruiting160Stichting European Myeloma NetworkFeb 2021
NCT04392037ICONIberdomide Combined With Low-dose Cyclophosphamide and DexamethasoneP2active not recruiting60Amsterdam UMC, location VUmcFeb 2021
NCT06179888Iberdomide Versus Observation Off Therapy After Idecabtagene Vicleucel CAR-T for Multiple MyelomaP2suspended78National Cancer Institute (NCI)Aug 2024
NCT05354557AHCTStudy of Iberdomide in People With Multiple Myeloma Who Have Had an Autologous Hematopoietic Stem Cell Transplant (AHCT)P2active not recruiting16Memorial Sloan Kettering Cancer CenterApr 2022
NCT06465316TECVAYLITesting Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple MyelomaP1recruiting26National Cancer Institute (NCI)Dec 2024
NCT06107738IBEXIberdomide and Daratumumab As Maintenance Therapy After an Autologous Stem Cell Transplant for Multiple MyelomaP2recruiting60Barbara Ann Karmanos Cancer InstituteDec 2023
NCT05560399CC-220A Study of Iberdomide (CC-220) in Combination With Elotuzumab and Dexamethasone for Relapsed/Refractory Multiple MyelomaEarly P1active not recruiting7Icahn School of Medicine at Mount SinaiFeb 2023
NCT05199311CC-220Carfilzomib, Iberdomide (CC-220) and Dexamethasone (KID) in Transplant Eligible Multiple MyelomaP1/P2recruiting66Hackensack Meridian HealthMay 2022
NCT07434960Expanded Access for Iberdomideavailable0Bristol-Myers Squibb
NCT05289492Study of Novel Regimens in Relapsed or Refractory Multiple MyelomaP1terminated16iTeos TherapeuticsMay 2022
NCT05899738CC-220A Study to Compare the Relative Bioavailability of Two Iberdomide (CC-220) Formulations and to Assess The Effect Of Food on the Drug Levels of Iberdomide in Healthy Adult ParticipantsP1completed32Bristol-Myers SquibbMay 2023
NCT04933747CC-220Study to Evaluate Safety and Tolerability of Iberdomide (CC-220) in Participants With Kidney Impairment Compared to Participants With Normal Kidney FunctionP1completed26CelgeneAug 2021

Iberdomide clinical trials: frequently asked questions

How many Iberdomide clinical trials are there?
35 Iberdomide clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 18 are actively recruiting participants. 2 are marked completed.
Are Iberdomide clinical trials recruiting in 2026?
Yes — 18 Iberdomide trials are actively recruiting in 2026, with 165 U.S. sites across 33 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Iberdomide being studied for?
Iberdomide is being studied for Multiple Myeloma, Refractory Multiple Myeloma, Recurrent Multiple Myeloma, Relapsed Multiple Myeloma, Non-Hodgkin Lymphoma and 12 more. The trials are grouped by indication on this page.
What phase is Iberdomide in?
Iberdomide clinical trials span 4 Phase 3, 12 Phase 2, 9 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Iberdomide clinical trials?
The lead sponsor across the most Iberdomide trials is Bristol-Myers Squibb, with 26 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Iberdomideas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

Last refreshed .

Related pages on Hipa.ai:

Iberdomide Clinical Trials (2026): 35 Studies | Hipa.ai