Iadademstat Clinical Trials (2026): 8 Studies for Acute Myeloid Leukemia & Acute Myeloid Leukemia Refractory
Hipa.ai Research · Source: ClinicalTrials.gov / AACT
Synced daily from ClinicalTrials.gov via AACT. Last sync: .
8 Iadademstat clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 7 indications (including Acute Myeloid Leukemia & Acute Myeloid Leukemia Refractory) and 273 total planned enrollment. 5 Iadademstat clinical trials are actively recruiting at 54 U.S. sites across 22 states. Most recent activity: NCT07113691 (Jan 2030).
Where to Participate: All Iadademstat Trial Sites in the U.S. (54 sites across 22 states)
Every actively recruiting Iadademstattrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.
| State | Facility | City | Trial | Map |
|---|---|---|---|---|
| AZ | Banner MD Anderson Cancer Center | Gilbert85234 | NCT05546580 | Map |
| AZ | The University of Arizona Cancer Center - North Campus | Tucson85724-5024 | NCT05546580 | Map |
| CA | City of Hope Comprehensive Cancer Center | Duarte91010 | NCT06287775 | Map |
| CA | City of Hope at Irvine Lennar | Irvine92618 | NCT06287775 | Map |
| CA | UC San Diego Moores Cancer Center | La Jolla92093 | NCT06287775 | Map |
| CA | University of California Davis Comprehensive Cancer Center | Sacramento95817 | NCT06287775 | Map |
| CT | Yale University | New Haven06520 | NCT06287775 | Map |
| CT | Yale University | New Haven06510 | NCT07113691 | Map |
| CT | Yale-New Haven Hospital North Haven Medical Center | North Haven06473 | NCT06287775 | Map |
| CT | Smilow Cancer Hospital Care Center-Trumbull | Trumbull06611 | NCT06287775 | Map |
| DC | MedStar Georgetown University Hospital | Washington D.C.20007 | NCT06287775 | Map |
| FL | UF Health Cancer Institute - Gainesville | Gainesville32610 | NCT06287775 | Map |
| FL | Miami Cancer Institute | Miami33176 | NCT05546580 | Map |
| FL | Sylvester Comprehensive Cancer Center | Miami33136 | NCT05546580 | Map |
| GA | Emory Saint Joseph's Hospital | Atlanta30342 | NCT06287775 | Map |
| GA | Emory University Hospital Midtown | Atlanta30308 | NCT06287775 | Map |
| GA | Emory University Hospital/Winship Cancer Institute | Atlanta30322 | NCT06287775 | Map |
| IL | University of Chicago Comprehensive Cancer Center | Chicago60637 | NCT06287775 | Map |
| IL | UC Comprehensive Cancer Center at Silver Cross | New Lenox60451 | NCT06287775 | Map |
| IL | University of Chicago Medicine-Orland Park | Orland Park60462 | NCT06287775 | Map |
| IN | UChicago Medicine Northwest Indiana | Crown Point46307 | NCT06287775 | Map |
| KS | University of Kansas Clinical Research Center | Fairway66205 | NCT06287775 | Map |
| KS | University of Kansas Cancer Center | Kansas City66160 | NCT06287775 | Map |
| KS | University of Kansas Hospital-Indian Creek Campus | Overland Park66211 | NCT06287775 | Map |
| KS | University of Kansas Hospital-Westwood Cancer Center | Westwood66205 | NCT06287775 | Map |
| KY | University of Kentucky/Markey Cancer Center | Lexington40536 | NCT06287775 | Map |
| MD | Johns Hopkins University/Sidney Kimmel Cancer Center | Baltimore21287 | NCT06287775 | Map |
| MD | The John Hopkins University School of Medicine | Baltimore21287-0013 | NCT05546580 | Map |
| MD | University of Maryland/Greenebaum Cancer Center | Baltimore21201 | NCT06287775 | Map |
| MA | Massachusetts General Hospital (MGH) | Boston02114 | NCT05546580 | Map |
| NJ | Memorial Sloan Kettering Basking Ridge | Basking Ridge07920 | NCT06287775 | Map |
| NJ | Memorial Sloan Kettering Monmouth | Middletown07748 | NCT06287775 | Map |
| NJ | Memorial Sloan Kettering Bergen | Montvale07645 | NCT06287775 | Map |
| NJ | Rutgers, The State University | Piscataway08854 | NCT05546580 | Map |
| NY | Memorial Sloan Kettering Commack | Commack11725 | NCT06287775 | Map |
| NY | Memorial Sloan Kettering Westchester | Harrison10604 | NCT06287775 | Map |
| NY | Icahn School of Medicine at Mount Sinai and Mount Sinai Hospital | New York10029 | NCT05546580 | Map |
| NY | Memorial Sloan Kettering Cancer Center | New York10065 | NCT06287775 | Map |
| NY | Memorial Sloan Kettering Nassau | Uniondale11553 | NCT06287775 | Map |
| NC | Carolinas Medical Center/Levine Cancer Institute | Charlotte28203 | NCT06287775 | Map |
| NC | Atrium Health Cabarrus/LCI-Concord | Concord28025 | NCT06287775 | Map |
| NC | Duke University Medical Center | Durham27705 | NCT05546580 | Map |
| NC | Wake Forest University Health Sciences | Winston-Salem27157 | NCT06287775 | Map |
| OH | Case Western Reserve University | Cleveland44106 | NCT06287775 | Map |
| OH | Ohio State University Comprehensive Cancer Center | Columbus43210 | NCT06287775 | Map |
| OR | OHSU Knight Cancer Institute | Portland97239 | NCT06357182 | Map |
| OR | Oregon Health & Science University | Portland97239 | NCT05546580 | Map |
| PA | University of Pittsburgh Cancer Institute (UPCI) | Pittsburgh15232 | NCT06287775 | Map |
| TN | Sarah Cannon Research Institute, LLC | Nashville37203 | NCT05546580 | Map |
| VA | University of Virginia Cancer Center | Charlottesville22908 | NCT06287775 | Map |
| VA | VCU Massey Comprehensive Cancer Center | Richmond23298 | NCT06287775 | Map |
| WV | West Virginia University | Morgantown26506 | NCT05546580 | Map |
| WI | Froedtert Hospital & the Medical College of Wisconsin | Milwaukee53226 | NCT06502145 | Map |
| WI | Froedtert Hospital & The Medical College of Wisconsin | Milwaukee53226 | NCT05546580 | Map |
Iadademstat clinical trials at a glance: phase × recruitment status
| Phase | recruiting | terminated | suspended | Total |
|---|---|---|---|---|
| P1 | 4 | 1 | 5 | |
| P1/P2 | 1 | 1 | ||
| P2 | 1 | 1 | 2 |
Recruiting Iadademstat clinical trials (5)
Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).
| NCT ID | Title | Phase | Indication | Enrollment | Started |
|---|---|---|---|---|---|
| NCT07113691 | TIARAIadademstat + SBRT With Atezo in ES-SCLC | P1 | Extensive Stage Small Cell Lung Cancer (ES-SCLC) | 15 | Jan 2026 |
| NCT06287775 | Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer | P1/P2 | Extensive Stage Lung Small Cell Carcinoma | 45 | Apr 2025 |
| NCT06502145 | Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome | P1 | Myelodysplastic Syndromes | 12 | Jan 2025 |
| NCT06357182 | Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia | P1 | Acute Myeloid Leukemia | 24 | Aug 2024 |
| NCT05546580 | FRIDAStudy of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+) | P1 | Acute Myeloid Leukemia, in Relapse | 50 | Nov 2022 |
Iadademstat clinical trials by indication
Acute Myeloid Leukemia (2)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06514261 | — | P1 | suspended | Testing the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AML |
| NCT06357182 | — | P1 | recruiting | Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia |
Extensive Stage Small Cell Lung Cancer (ES-SCLC) (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07113691 | TIARA | P1 | recruiting | Iadademstat + SBRT With Atezo in ES-SCLC |
Accelerated Phase Myeloproliferative Neoplasm (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06661915 | — | P2 | suspended | A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs) |
Extensive Stage Lung Small Cell Carcinoma (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06287775 | — | P1/P2 | recruiting | Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer |
Myelodysplastic Syndromes (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06502145 | — | P1 | recruiting | Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome |
Small-cell Lung Cancer (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT05420636 | — | P2 | terminated | Iadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NET |
Acute Myeloid Leukemia, in Relapse (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT05546580 | FRIDA | P1 | recruiting | Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+) |
Terminated and withdrawn Iadademstat trials (3)
Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.
- NCT06661915suspendedA Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)
- NCT06514261suspendedTesting the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AML
- NCT05420636terminatedIadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NET
All Iadademstat trials (8)
Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.
| NCT ID | Acronym | Title | Phase | Status | Enrollment | Sponsor | Started |
|---|---|---|---|---|---|---|---|
| NCT07113691 | TIARA | Iadademstat + SBRT With Atezo in ES-SCLC | P1 | recruiting | 15 | Yale University | Jan 2026 |
| NCT06287775 | Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer | P1/P2 | recruiting | 45 | National Cancer Institute (NCI) | Apr 2025 | |
| NCT06661915 | A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs) | P2 | suspended | 62 | National Cancer Institute (NCI) | Aug 2025 | |
| NCT06502145 | Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome | P1 | recruiting | 12 | Medical College of Wisconsin | Jan 2025 | |
| NCT06514261 | Testing the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AML | P1 | suspended | 45 | National Cancer Institute (NCI) | Dec 2024 | |
| NCT06357182 | Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia | P1 | recruiting | 24 | OHSU Knight Cancer Institute | Aug 2024 | |
| NCT05546580 | FRIDA | Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+) | P1 | recruiting | 50 | Oryzon Genomics S.A. | Nov 2022 |
| NCT05420636 | Iadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NET | P2 | terminated | 20 | Fox Chase Cancer Center | Dec 2022 |
Iadademstat clinical trials: frequently asked questions
- How many Iadademstat clinical trials are there?
- 8 Iadademstat clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 5 are actively recruiting participants.
- Are Iadademstat clinical trials recruiting in 2026?
- Yes — 5 Iadademstat trials are actively recruiting in 2026, with 54 U.S. sites across 22 states. See the recruiting trials and the per-state site list further down this page.
- What conditions is Iadademstat being studied for?
- Iadademstat is being studied for Acute Myeloid Leukemia, Acute Myeloid Leukemia Refractory, Acute Myeloid Leukemia, in Relapse, Blast Phase Myeloproliferative Neoplasm, Essential Thrombocythemia and 13 more. The trials are grouped by indication on this page.
- What phase is Iadademstat in?
- Iadademstat clinical trials span 2 Phase 2, 5 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
- Who sponsors Iadademstat clinical trials?
- The lead sponsor across the most Iadademstat trials is National Cancer Institute (NCI), with 5 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.
Sources and methodology
Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Iadademstatas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.
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