Golimumab Clinical Trials (2026): 102 Studies for Rheumatoid Arthritis & Colitis, Ulcerative

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

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102 Golimumab clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 39 indications (including Rheumatoid Arthritis & Colitis, Ulcerative) and 35,502 total planned enrollment. 31 Phase 3 Golimumab trials and 17 Phase 2, 22 Phase 4 are listed. 7 Golimumab clinical trials are actively recruiting at 16 U.S. sites across 11 states. Most recent activity: NCT04725422 (Aug 2050).

Where to Participate: All Golimumab Trial Sites in the U.S. (16 sites across 11 states)

Every actively recruiting Golimumabtrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
FLFamily Arthritis CenterLoxahatchee Groves33470NCT05669833Map
FLHealing RheumatologyPlant City33563NCT05669833Map
FLSouthwest Florida RheumatologyRiverview33569NCT05669833Map
GAParris and AssociatesLilburn30047NCT05669833Map
MAUniversity of Massachusetts Chan Medical SchoolWorcester01655NCT05669833Map
NEUniversity of Nebraska Medical CenterOmaha68198NCT03414502Map
NEUniversity of Nebraska Medical CenterOmaha68198NCT05669833Map
NYNew York UniversityNew York10016NCT05669833Map
OHCincy ArthritisBlue Ash45242NCT05669833Map
OHSouthern Ohio RheumatologyWheelersburg45694NCT05669833Map
PAHospital at the University of PennsylvaniaPhiladelphia19104NCT05669833Map
TNCumberland RheumatologyCrossville38555NCT05669833Map
TXHeritage Rheumatology and Arthritis CareColleyville76034NCT05669833Map
TXTexas Arthritis CenterEl Paso79902NCT05669833Map
UTUniversity of UtahSalt Lake City84132NCT05669833Map
WASeattle Children's HospitalSeattle98105NCT04725422Map

Golimumab clinical trials at a glance: phase × recruitment status

Phaserecruitingactive not recruitingcompletedterminatedwithdrawnnot yet recruitingunknownno longer availableTotal
Early P111
P155
P1/P211
P213822117
P2/P3112
P321234131
P41142522
N/A111415123

Recruiting Golimumab clinical trials (7)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT04725422CHOIRCHronic Nonbacterial Osteomyelitis International RegistryChronic Nonbacterial Osteomyelitis2,000Aug 2018
NCT03414502Treatment of Rheumatoid Arthritis With DMARDs: Predictors of ResponseP3Rheumatoid Arthritis400Dec 2007
NCT07258108Sac-TMT Plus KL-A167 in PD-L1+, HR+/HER2- Metastatic Breast Cancer After CDK4/6 InhibitorsP2Breast Cancer35Nov 2025
NCT07138898Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyP2Rheumatic Disease80Sep 2025
NCT07495644Efficacy of Different Biological Treatments in Patients With Inflammatory Bowel Disease After One Year of Treatment in Upper EgyptInflamatory Bowel Disease (Crohn's and Ulcerative Colitis)95Mar 2026
NCT05669833EVOLUTIONGuselkumab vs Golimumab in PsA TNF Inadequate Responder PatientsP3Psoriatic Arthritis63Jul 2023
NCT05313620Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic EventsP4Ulcerative Colitis30Apr 2022

Golimumab clinical trials by indication

Rheumatoid Arthritis (16)

NCTAcronymPhaseStatusTitle
NCT03414502P3recruitingTreatment of Rheumatoid Arthritis With DMARDs: Predictors of Response
NCT05842213ALVOFLEXP3completedComparative, Multicenter Study in Subjects with Rheumatoid Arthritis, ALVOFLEX
NCT03100253RAFTINGP4terminatedRheumatoid Arthritis Treatment After First Anti-TNF INvestiGation
NCT01602302RA-BioStopP4terminatedUltrasound and Withdrawal of Biological DMARDs in Rheumatoid Arthritis
NCT02414984Go-Compl-ArN/AterminatedRegistry for Analysis of Compliance in Colombian Participants With Rheumatoid Arthritis Exposed to Golimumab
NCT02390700GO-IVN/AterminatedObservational Study of Golimumab Intravenous Infusion
NCT01295151SWITCHP4completedSWITCH Clinical Trial for Patients With Rheumatoid Arthritis Who Have Failed an Initial TNF-blocking Drug.
NCT01081717N/AcompletedGolimumab Safety and Surveillance Program Using the Ingenix NHI Database
+ 8 more, see All trials below.

Colitis, Ulcerative (12)

NCTAcronymPhaseStatusTitle
NCT05242484DUET-UCP2active not recruitingA Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT03596645PURSUIT 2P3active not recruitingA Study to Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis
NCT01900574P1completedA Study to Assess the Safety and Pharmacokinetics of Subcutaneously Administered Golimumab, a Human Anti-TNFα Antibody, in Pediatric Patients With Moderate to Severe Active Ulcerative Colitis
NCT03662542VEGAP2completedA Study of Efficacy and Safety of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT03669029P4unknownOptimization of Golimumab Treatment in Ulcerative Colitis
NCT02318667EVOLUTIONP4completedCorrelation of Soluble Suppression of Tumorigenicity 2 (ST2) With Golimumab (MK-8259) Response in Participants With Ulcerative Colitis (UC) (MK-8529-022).
NCT02412085UC-GOLP4unknownGolimumab in Steroid-dependent Ulcerative Colitis: Induction and Maintenance of Clinical and Endoscopic Remission
NCT01988961P2completedA Study to Evaluate the Accuracy of a Subset of the Length-109 Probe Set Panel (a Genetic Test) in Predicting Response to Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis
+ 4 more, see All trials below.

Ulcerative Colitis (11)

NCTAcronymPhaseStatusTitle
NCT05313620P4recruitingEffect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic Events
NCT04156984P4completedComparison of Two Different Golimumab Dosing Regimens for Ulcerative Colitis
NCT05530122biologicalN/AcompletedPrognosis in UC After First Biological
NCT03182166GOLILORP2completedGolimumab in Ulcerative Colitis (UC) Patients With Loss of Response (LOR) Followed by Dose Optimization
NCT05405465N/AcompletedEffectiveness of Golimumab in Patients With Ulcerative Colitis: Results of a Real-life Study in Switzerland
NCT03018925GOLI2015N/AcompletedGolimumab Effect in the Modulation of Gut Microbiota in Ulcerative Colitis
NCT03124121GO-LEVELP4completedStudy of the Golimumab Exposure-Response Relationship Using Serum Trough Levels
NCT03394586N/AunknownReal-world Data Regarding Treatment of Ulcerative Colitis Patients With Golimumab
+ 3 more, see All trials below.

Psoriatic Arthritis (7)

NCTAcronymPhaseStatusTitle
NCT05669833EVOLUTIONP3recruitingGuselkumab vs Golimumab in PsA TNF Inadequate Responder Patients
NCT04610476P3unknownImpact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic Arthritis
NCT04108468GOLMePsAP3completedGOLimumab and Methotrexate Versus Methotrexate in Very Early PsA
NCT03955861N/AcompletedUltrasound Enthesitis Response in Psoriatic Arthritis
NCT01871649P3completedInitial Treatment With Golimumab in Early PsA
NCT02841176Go-ThermalN/AterminatedThermography in Assessing Treatment Response to Golimumab in Psoriatic Arthritis
NCT02065713GO-DACTP3completedEfficacy of Golimumab in Combination With Methotrexate (MTX) Versus MTX Monotherapy, in Improving Dactylitis, in MTX naïve Psoriatic Arthritis Patients

Arthritis, Rheumatoid (7)

NCTAcronymPhaseStatusTitle
NCT03729349GO FARN/AcompletedGolimumab for Adherence in Rheumatoid Arthritis
NCT04188249N/AunknownEffectiveness and Adherence of Golimumab in Rheumatoid Arthritis
NCT02728934AWAREN/AcompletedComparative and Pragmatic Study of Golimumab Intravenous (IV) (Simponi Aria) Versus Infliximab (Remicade) in Rheumatoid Arthritis
NCT01962974REGAINP3terminatedA Golimumab Phase 3b, Multicenter, Assessment of Intravenous Efficacy in Rheumatoid Arthritis Subjects Who Have Diminished Disease Control Despite Treatment With Infliximab (REMICADE®)
NCT00973479P3completedAn Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate Therapy
NCT00299546CNTO 148P3completedA Study of the Safety and Efficacy of Golimumab (CNTO 148) in Subjects With Active Rheumatoid Arthritis Previously Treated With Biologic Anti-TNFa Agent(s)
NCT00975130GO-MOREP3completedSubcutaneous Golimumab (GLM) Plus DMARDs for Rheumatoid Arthritis, Followed by Intravenous/Subcutaneous GLM Strategy (P06129 AM2)

Ankylosing Spondylitis (6)

NCTAcronymPhaseStatusTitle
NCT05164198RECASTP4unknownREduCed Dose of TNFi in Patients With Ankylosing SpondyliTis (RECAST)
NCT03557853GO-COXN/AcompletedClinical and Radiological Manifestations of Coxitis in Patients With Ankylosing Spondylitis Treated With Golimumab
NCT02758782CONSULP4completedNSAIDs Added to Anti-TNF Therapy Versus Anti-TNF Therapy Alone on Progression of Structural Damage in Ankylosing Spondylitis
NCT02186873P3completedA Study of Golimumab in Participants With Active Ankylosing Spondylitis
NCT01668004GO-EASYP4completedThe Incidence of Extra-Articular Manifestations in Participants With Ankylosing Spondylitis Treated With Golimumab (MK-8259-012)
NCT01248793P3completedStudy of the Safety and Efficacy of Golimumab in Chinese Patients With Ankylosing Spondylitis

Arthritis, Psoriatic (3)

NCTAcronymPhaseStatusTitle
NCT05071664AFFINITYP2completedA Study of Guselkumab and Golimumab Combination Therapy in Participants With Active Psoriatic Arthritis
NCT02181673P3completedA Study of Golimumab in Participants With Active Psoriatic Arthritis
NCT00265096GO-REVEALP3completedA Study of the Safety and Efficacy of Golimumab in Patients With Active Psoriatic Arthritis

Diabetes Mellitus, Type 1 (3)

NCTAcronymPhaseStatusTitle
NCT04729296P2withdrawnAnti-TNFα to Delay or Prevent Progression to Stage 3 T1D
NCT02846545T1GERP2completedA Study of SIMPONI® to Arrest Beta-cell Loss in Type 1 Diabetes
NCT03945903N/Ano longer availablePre-Approval Access to Golimumab Subcutaneous for the Treatment of Stage 3 Type-1 Diabetes Mellitus in Children and Young Adults

Spondylitis, Ankylosing (3)

NCTAcronymPhaseStatusTitle
NCT03733925P4completedA Study of Golimumab in the Treatment of Indian Participants With Active Spondyloarthropathy of Ankylosing Spondylitis or Psoriatic Arthritis
NCT01453725GO-AHEADP3completedEffect of Golimumab in Participants With Active Axial Spondyloarthritis (P07642, MK-8259-006)
NCT00265083P3completedA Study of the Safety and Efficacy of Golimumab in Subjects With Active Ankylosing Spondylitis

Axial Spondyloarthritis (3)

NCTAcronymPhaseStatusTitle
NCT03270501GO-GUTP3completedEfficacy of Golimumab in Early Axial Spondyloarthritis in Relation to Gut Inflammation
NCT02437162P3terminatedA Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Anti-TNFα Naive Participants With Active Radiographic Axial Spondyloarthritis
NCT02438787P3terminatedA Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Anti-TNF(Alpha) Refractory Participants With Active Radiographic Axial Spondyloarthritis

Major Depressive Disorder (2)

NCTAcronymPhaseStatusTitle
NCT04156425N/AunknownThe Role of PKC Activation in the Immune-inflammatory Mechanism of Major Depressive Depression
NCT04531423N/AunknownPKC as Serum Biomarkers for Depression

Spondyloarthritis (2)

NCTAcronymPhaseStatusTitle
NCT03253796GO-BACKP4completedGolimumab (MK-8259 / SCH900259) Treatment Withdrawal in Participants With Non-radiographic Axial Spondyloarthritis (GO-BACK) (MK-8259-038)
NCT01610947SPACINGN/AcompletedEffect of Spacing of Anti-TNF Drugs in Ankylosing Spondylitis With Low Disease Activity

Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis) (1)

NCTAcronymPhaseStatusTitle
NCT07495644N/Anot yet recruitingEfficacy of Different Biological Treatments in Patients With Inflammatory Bowel Disease After One Year of Treatment in Upper Egypt

Breast Cancer (1)

NCTAcronymPhaseStatusTitle
NCT07258108P2recruitingSac-TMT Plus KL-A167 in PD-L1+, HR+/HER2- Metastatic Breast Cancer After CDK4/6 Inhibitors

Rheumatic Disease (1)

NCTAcronymPhaseStatusTitle
NCT07138898P2not yet recruitingImmunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty

Metastatic Castration-Resistant Prostate Carcinoma (1)

NCTAcronymPhaseStatusTitle
NCT05960578P2active not recruitingGolimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP Study

Crohn's Disease (1)

NCTAcronymPhaseStatusTitle
NCT05242471DUET-CDP2active not recruitingA Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease

Infection (1)

NCTAcronymPhaseStatusTitle
NCT04115423N/AunknownA Retrospective Cohort Study on the Risk of Serious Infections in Rheumatoid Arthritis Patients Receiving Tocilizumab

Behcet Syndrome (1)

NCTAcronymPhaseStatusTitle
NCT04218565P2terminatedGolimumab for the Treatment of Refractory Behcet's Uveitis

Inflammatory Bowel Diseases (1)

NCTAcronymPhaseStatusTitle
NCT03885713BioIBDP4completedIdentification of Predictive Biomarkers for Response to Biologic Therapies and Tofacitinib in Inflammatory Bowel Disease

Type 1 Diabetes Mellitus (1)

NCTAcronymPhaseStatusTitle
NCT03632759Early P1completedTargeting Beta Cell Dysfunction With Liraglutide or Golimumab in Longstanding T1D

Chronic Nonbacterial Osteomyelitis (1)

NCTAcronymPhaseStatusTitle
NCT04725422CHOIRN/ArecruitingCHronic Nonbacterial Osteomyelitis International Registry

Pre-Symptomatic Type 1 Diabetes (1)

NCTAcronymPhaseStatusTitle
NCT03298542P1completedA Study to Evaluate SIMPONI (Golimumab) Therapy in Children, Adolescents and Young Adults With Pre-Symptomatic Type 1 Diabetes

ULCERATIVE COLITIS (1)

NCTAcronymPhaseStatusTitle
NCT02425865In-TARGETP4completedIntensive Treatment to Reach the Target With Golimumab in ulcErative coliTis - In-TARGET

RheumatoId Arthritis (1)

NCTAcronymPhaseStatusTitle
NCT03016260RABIOPREDN/AterminatedRABIOPRED - a Validation Study of Theranostic Test to PREDict Treatment Response of Anti-TNFα BIologicals in Rheumatoid Arthritis

Colitis (1)

NCTAcronymPhaseStatusTitle
NCT02687724GOAL-ARCP4unknownGolimumab (GLM) Dose Optimisation to Adequate Levels to Achieve Response in Colitis

Inflammatory Bowel Disease (1)

NCTAcronymPhaseStatusTitle
NCT03043677N/AcompletedEx-vivo Modulatory Effect of Biological Drugs for Inflammatory Bowel Disease on the Mucosa and on Peripheral Blood Mononuclear Cells

Arthritis, Juvenile (1)

NCTAcronymPhaseStatusTitle
NCT02277444GO-VIVAP3completedA Study to Evaluate the Pharmacokinetics, Efficacy and Safety of Intravenous Golimumab in Pediatric Participants With Active Polyarticular Course Juvenile Idiopathic Arthritis Despite Methotrexate Therapy

Hepatosplenic T-Cell Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT01804166HSTCLP4completedA Research Study to Bank Samples for Future Evaluation to Identify Biomarkers That Predispose Crohn's Disease and Ulcerative Colitis Patients to Develop Hepatosplenic T-Cell Lymphoma (HSTCL)

Spondyloarthropathy (1)

NCTAcronymPhaseStatusTitle
NCT01718951P4completedGolimumab Versus Pamidronate for the Treatment of Axial Spondyloarthropathy: a 48-week Trial

Autoimmune Inner Ear Disease (1)

NCTAcronymPhaseStatusTitle
NCT01526174AIEDP1/P2terminatedIntratympanic Injection for Autoimmune Inner Ear Disease

Peripheral Spondylarthritis (1)

NCTAcronymPhaseStatusTitle
NCT01426815CRESPAP3completedExploration of TNF-alpha Blockade With Golimumab in the Induction of Clinical Remission in Patients With Early Peripheral Spondyloarthritis (SpA) According to ASAS-criteria

Juvenile Idiopathic Arthritis (1)

NCTAcronymPhaseStatusTitle
NCT01230827JIAP3terminatedA Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate (GO KIDS)

Healthy Volunteers (1)

NCTAcronymPhaseStatusTitle
NCT01258777P1completedA Study of the Pharmacokinetics of Golimumab in Japanese and Caucasian Male Subjects

Healthy Adult Chinese Males (1)

NCTAcronymPhaseStatusTitle
NCT01288157P1completedA Study of the Pharmacokinetics of Golimumab in Chinese Male Subjects

JIA Associated Uveitis (1)

NCTAcronymPhaseStatusTitle
NCT04200833N/AcompletedGolimumab in Juvenile Idiopathic Arthritis-associated Uveitis Failing Adalimumab

Arthritis (1)

NCTAcronymPhaseStatusTitle
NCT01004432ENBRELP3completedGolimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)

Sarcoidosis (1)

NCTAcronymPhaseStatusTitle
NCT00955279SCP2completedA Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis

Asthma (1)

NCTAcronymPhaseStatusTitle
NCT00675649P2withdrawnA Clinical Trial Evaluating the Safety and Effectiveness of Golimumab in Patients With Severe, Persistent Asthma

Golimumab pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

AcronymNCTPhaseStatusIndicationEnrollmentPubMed
BioIBDNCT03885713P4completedInflammatory Bowel Diseases180PMID 26353983
RECASTNCT05164198P4unknownAnkylosing Spondylitis448
In-TARGETNCT02425865P4completedULCERATIVE COLITIS202
RAFTINGNCT03100253P4terminatedRheumatoid Arthritis208
GO-BACKNCT03253796P4completedSpondyloarthritis323PMID 36919768
CONSULNCT02758782P4completedAnkylosing Spondylitis156PMID 28601821
RA-BioStopNCT01602302P4terminatedRheumatoid Arthritis40
GOAL-ARCNCT02687724P4unknownColitis136
HSTCLNCT01804166P4completedHepatosplenic T-Cell Lymphoma1
GO-LEVELNCT03124121P4completedUlcerative Colitis112PMID 32506695
EVOLUTIONNCT02318667P4completedColitis, Ulcerative38PMID 31516554
UC-GOLNCT02412085P4unknownColitis, Ulcerative100
GO-COLITISNCT02092285P4completedUlcerative Colitis205PMID 30002864
PIMSNCT02186886P4unknownUlcerative Colitis50
SWITCHNCT01295151P4completedRheumatoid Arthritis122PMID 32859608
SMARTNCT02155335P4completedUlcerative Colitis100PMID 29920582
GO-EASYNCT01668004P4completedAnkylosing Spondylitis101PMID 30385705
PURSUIT 2NCT03596645P3active not recruitingColitis, Ulcerative84PMID 41503939
EVOLUTIONNCT05669833P3recruitingPsoriatic Arthritis63PMID 40102973
GO-VIVANCT02277444P3completedArthritis, Juvenile130PMID 33493312
ALVOFLEXNCT05842213P3completedRheumatoid Arthritis502PMID 41182658
GO-GUTNCT03270501P3completedAxial Spondyloarthritis64PMID 23139267
GOLMePsANCT04108468P3completedPsoriatic Arthritis84
CRESPANCT01426815P3completedPeripheral Spondylarthritis60PMID 36200875
GO-DACTNCT02065713P3completedPsoriatic Arthritis44PMID 32193187
CNTO 148NCT00488631P3completedColitis, Ulcerative1,228PMID 37691729
GO-AHEADNCT01453725P3completedSpondylitis, Ankylosing198PMID 26139307
REGAINNCT01962974P3terminatedArthritis, Rheumatoid7
JIANCT01230827P3terminatedJuvenile Idiopathic Arthritis173PMID 28507219
ENBRELNCT01004432P3completedArthritis433PMID 28035867
CNTO 148NCT00299546P3completedArthritis, Rheumatoid461PMID 27889300
GO-FORWARDNCT00264550P3completedRheumatoid Arthritis444PMID 21083889
GO-MORENCT00975130P3completedArthritis, Rheumatoid3,366PMID 23740226
GO-REVEALNCT00265096P3completedArthritis, Psoriatic407PMID 27803138
DUET-CDNCT05242471P2active not recruitingCrohn's Disease703
DUET-UCNCT05242484P2active not recruitingColitis, Ulcerative577
AFFINITYNCT05071664P2completedArthritis, Psoriatic91
GOLILORNCT03182166P2completedUlcerative Colitis51
VEGANCT03662542P2completedColitis, Ulcerative214PMID 38488354
T1GERNCT02846545P2completedDiabetes Mellitus, Type 184PMID 33207093
SCNCT00955279P2completedSarcoidosis173PMID 25594886
REGN88NCT01217814P2terminatedRheumatoid Arthritis16

Terminated and withdrawn Golimumab trials (16)

Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.

All Golimumab trials (102)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT04725422CHOIRCHronic Nonbacterial Osteomyelitis International Registryrecruiting2,000Seattle Children's HospitalAug 2018
NCT05242471DUET-CDA Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's DiseaseP2active not recruiting703Janssen Research & Development, LLCJul 2022
NCT03414502Treatment of Rheumatoid Arthritis With DMARDs: Predictors of ResponseP3recruiting400University of NebraskaDec 2007
NCT05242484DUET-UCA Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative ColitisP2active not recruiting577Janssen Research & Development, LLCSep 2022
NCT07258108Sac-TMT Plus KL-A167 in PD-L1+, HR+/HER2- Metastatic Breast Cancer After CDK4/6 InhibitorsP2recruiting35Sun Yat-sen UniversityNov 2025
NCT07138898Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyP2not yet recruiting80NYU Langone HealthSep 2025
NCT04729296Anti-TNFα to Delay or Prevent Progression to Stage 3 T1DP2withdrawn0National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Jul 2021
NCT07495644Efficacy of Different Biological Treatments in Patients With Inflammatory Bowel Disease After One Year of Treatment in Upper Egyptnot yet recruiting95Assiut UniversityMar 2026
NCT05960578Golimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP StudyP2active not recruiting8University of WashingtonMay 2024
NCT03596645PURSUIT 2A Study to Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative ColitisP3active not recruiting84Janssen Research & Development, LLCOct 2018
NCT05669833EVOLUTIONGuselkumab vs Golimumab in PsA TNF Inadequate Responder PatientsP3recruiting63University of PennsylvaniaJul 2023
NCT05313620Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic EventsP4recruiting30Fundación de Investigación Biomédica - Hospital Universitario de La PrincesaApr 2022
NCT04610476Impact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic ArthritisP3unknown270University of Erlangen-Nürnberg Medical SchoolOct 2020
NCT04156425The Role of PKC Activation in the Immune-inflammatory Mechanism of Major Depressive DepressionN/Aunknown180Shanghai Mental Health CenterJul 2020
NCT03885713BioIBDIdentification of Predictive Biomarkers for Response to Biologic Therapies and Tofacitinib in Inflammatory Bowel DiseaseP4completed180Fundación de Investigación Biomédica - Hospital Universitario de La PrincesaSep 2019
NCT05164198RECASTREduCed Dose of TNFi in Patients With Ankylosing SpondyliTis (RECAST)P4unknown448Hanyang University Seoul HospitalJan 2022
NCT02277444GO-VIVAA Study to Evaluate the Pharmacokinetics, Efficacy and Safety of Intravenous Golimumab in Pediatric Participants With Active Polyarticular Course Juvenile Idiopathic Arthritis Despite Methotrexate TherapyP3completed130Janssen Research & Development, LLCDec 2014
NCT05842213ALVOFLEXComparative, Multicenter Study in Subjects with Rheumatoid Arthritis, ALVOFLEXP3completed502Alvotech Swiss AGMar 2023
NCT05071664AFFINITYA Study of Guselkumab and Golimumab Combination Therapy in Participants With Active Psoriatic ArthritisP2completed91Janssen Research & Development, LLCOct 2021
NCT04156984Comparison of Two Different Golimumab Dosing Regimens for Ulcerative ColitisP4completed27David DrobneApr 2021
NCT03270501GO-GUTEfficacy of Golimumab in Early Axial Spondyloarthritis in Relation to Gut InflammationP3completed64University GhentNov 2017
NCT04108468GOLMePsAGOLimumab and Methotrexate Versus Methotrexate in Very Early PsAP3completed84The Leeds Teaching Hospitals NHS TrustOct 2015
NCT03729349GO FARGolimumab for Adherence in Rheumatoid Arthritiscompleted222Janssen Inc.Jan 2019
NCT02425865In-TARGETIntensive Treatment to Reach the Target With Golimumab in ulcErative coliTis - In-TARGETP4completed202Groupe d'Etude Therapeutique des Affections Inflammatoires DigestivesDec 2016
NCT04218565Golimumab for the Treatment of Refractory Behcet's UveitisP2terminated1Wenjie ZhengFeb 2020
NCT04531423PKC as Serum Biomarkers for DepressionN/Aunknown100Shanghai Mental Health CenterOct 2020
NCT01900574A Study to Assess the Safety and Pharmacokinetics of Subcutaneously Administered Golimumab, a Human Anti-TNFα Antibody, in Pediatric Patients With Moderate to Severe Active Ulcerative ColitisP1completed35Janssen Research & Development, LLCAug 2013
NCT05530122biologicalPrognosis in UC After First Biologicalcompleted192Tampere University HospitalJan 2009
NCT03100253RAFTINGRheumatoid Arthritis Treatment After First Anti-TNF INvestiGationP4terminated208Mario Negri Institute for Pharmacological ResearchMar 2018
NCT03182166GOLILORGolimumab in Ulcerative Colitis (UC) Patients With Loss of Response (LOR) Followed by Dose OptimizationP2completed51Centre Hospitalier Universitaire de Saint EtienneNov 2017
NCT03733925A Study of Golimumab in the Treatment of Indian Participants With Active Spondyloarthropathy of Ankylosing Spondylitis or Psoriatic ArthritisP4completed100Johnson & Johnson Private LimitedJan 2019
NCT03662542VEGAA Study of Efficacy and Safety of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative ColitisP2completed214Janssen Research & Development, LLCNov 2018
NCT03632759Targeting Beta Cell Dysfunction With Liraglutide or Golimumab in Longstanding T1DEarly P1completed16Carla Greenbaum, MDAug 2018
NCT04115423A Retrospective Cohort Study on the Risk of Serious Infections in Rheumatoid Arthritis Patients Receiving Tocilizumabunknown9,508Sungkyunkwan UniversityApr 2020
NCT04200833Golimumab in Juvenile Idiopathic Arthritis-associated Uveitis Failing Adalimumabcompleted10Medical University of GrazMar 2010
NCT03955861Ultrasound Enthesitis Response in Psoriatic Arthritiscompleted80Belfast Health and Social Care TrustFeb 2019
NCT03557853GO-COXClinical and Radiological Manifestations of Coxitis in Patients With Ankylosing Spondylitis Treated With Golimumabcompleted39MSD Pharmaceuticals LLCJun 2016
NCT05405465Effectiveness of Golimumab in Patients With Ulcerative Colitis: Results of a Real-life Study in Switzerlandcompleted103University of ZurichJan 2018
NCT03298542A Study to Evaluate SIMPONI (Golimumab) Therapy in Children, Adolescents and Young Adults With Pre-Symptomatic Type 1 DiabetesP1completed8Janssen Research & Development, LLCOct 2017
NCT03253796GO-BACKGolimumab (MK-8259 / SCH900259) Treatment Withdrawal in Participants With Non-radiographic Axial Spondyloarthritis (GO-BACK) (MK-8259-038)P4completed323Merck Sharp & Dohme LLCNov 2017
NCT04188249Effectiveness and Adherence of Golimumab in Rheumatoid Arthritisunknown200Peking Union Medical College HospitalJul 2019
NCT02758782CONSULNSAIDs Added to Anti-TNF Therapy Versus Anti-TNF Therapy Alone on Progression of Structural Damage in Ankylosing SpondylitisP4completed156Charite University, Berlin, GermanySep 2016
NCT02846545T1GERA Study of SIMPONI® to Arrest Beta-cell Loss in Type 1 DiabetesP2completed84Janssen Research & Development, LLCAug 2016
NCT01602302RA-BioStopUltrasound and Withdrawal of Biological DMARDs in Rheumatoid ArthritisP4terminated40Medical University of GrazJun 2012
NCT03018925GOLI2015Golimumab Effect in the Modulation of Gut Microbiota in Ulcerative Colitiscompleted15Institut d'Investigació Biomèdica de Girona Dr. Josep TruetaOct 2016
NCT02687724GOAL-ARCGolimumab (GLM) Dose Optimisation to Adequate Levels to Achieve Response in ColitisP4unknown136University College DublinJun 2016
NCT01804166HSTCLA Research Study to Bank Samples for Future Evaluation to Identify Biomarkers That Predispose Crohn's Disease and Ulcerative Colitis Patients to Develop Hepatosplenic T-Cell Lymphoma (HSTCL)P4completed1Janssen Scientific Affairs, LLCMar 2013
NCT02728934AWAREComparative and Pragmatic Study of Golimumab Intravenous (IV) (Simponi Aria) Versus Infliximab (Remicade) in Rheumatoid Arthritiscompleted1,279Janssen Scientific Affairs, LLCFeb 2016
NCT03669029Optimization of Golimumab Treatment in Ulcerative ColitisP4unknown50Hospital de ManisesOct 2018
NCT03016260RABIOPREDRABIOPRED - a Validation Study of Theranostic Test to PREDict Treatment Response of Anti-TNFα BIologicals in Rheumatoid Arthritisterminated250TcLand Expression S.A.Dec 2016
NCT03124121GO-LEVELStudy of the Golimumab Exposure-Response Relationship Using Serum Trough LevelsP4completed112Guy's and St Thomas' NHS Foundation TrustSep 2017
NCT03945903Pre-Approval Access to Golimumab Subcutaneous for the Treatment of Stage 3 Type-1 Diabetes Mellitus in Children and Young Adultsno longer available0Janssen Research & Development, LLC
NCT01426815CRESPAExploration of TNF-alpha Blockade With Golimumab in the Induction of Clinical Remission in Patients With Early Peripheral Spondyloarthritis (SpA) According to ASAS-criteriaP3completed60University Hospital, GhentMar 2012
NCT03394586Real-world Data Regarding Treatment of Ulcerative Colitis Patients With Golimumabunknown100University of ZurichJan 2018
NCT01871649Initial Treatment With Golimumab in Early PsAP3completed51Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Aug 2013
NCT01610947SPACINGEffect of Spacing of Anti-TNF Drugs in Ankylosing Spondylitis With Low Disease ActivityN/Acompleted398University Hospital, MontpellierMay 2012
NCT03043677Ex-vivo Modulatory Effect of Biological Drugs for Inflammatory Bowel Disease on the Mucosa and on Peripheral Blood Mononuclear Cellscompleted45Fundación de Investigación Biomédica - Hospital Universitario de La PrincesaApr 2016
NCT02841176Go-ThermalThermography in Assessing Treatment Response to Golimumab in Psoriatic ArthritisN/Aterminated4Imperial College Healthcare NHS TrustJul 2016
NCT02437162A Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Anti-TNFα Naive Participants With Active Radiographic Axial SpondyloarthritisP3terminated347Janssen Research & Development, LLCSep 2015
NCT02318667EVOLUTIONCorrelation of Soluble Suppression of Tumorigenicity 2 (ST2) With Golimumab (MK-8259) Response in Participants With Ulcerative Colitis (UC) (MK-8529-022).P4completed38Merck Sharp & Dohme LLCFeb 2015
NCT02438787A Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Anti-TNF(Alpha) Refractory Participants With Active Radiographic Axial SpondyloarthritisP3terminated315Janssen Research & Development, LLCJul 2015
NCT02065713GO-DACTEfficacy of Golimumab in Combination With Methotrexate (MTX) Versus MTX Monotherapy, in Improving Dactylitis, in MTX naïve Psoriatic Arthritis PatientsP3completed44Instituto de Medicina Molecular João Lobo AntunesAug 2014
NCT02181673A Study of Golimumab in Participants With Active Psoriatic ArthritisP3completed480Janssen Research & Development, LLCSep 2014
NCT02412085UC-GOLGolimumab in Steroid-dependent Ulcerative Colitis: Induction and Maintenance of Clinical and Endoscopic RemissionP4unknown100Istituto Clinico HumanitasMar 2015
NCT02414984Go-Compl-ArRegistry for Analysis of Compliance in Colombian Participants With Rheumatoid Arthritis Exposed to Golimumabterminated37Janssen-Cilag, S.A.Mar 2015
NCT02390700GO-IVObservational Study of Golimumab Intravenous Infusionterminated78Janssen Inc.Feb 2015
NCT02186873A Study of Golimumab in Participants With Active Ankylosing SpondylitisP3completed208Janssen Research & Development, LLCSep 2014
NCT02092285GO-COLITISGolimumab Utilization and Impact on Ulcerative Colitis (MK-8259-032)P4completed205Merck Sharp & Dohme LLCMay 2014
NCT01988961A Study to Evaluate the Accuracy of a Subset of the Length-109 Probe Set Panel (a Genetic Test) in Predicting Response to Golimumab in Participants With Moderately to Severely Active Ulcerative ColitisP2completed103Janssen Research & Development, LLCDec 2013
NCT01863771A Safety and Effectiveness Study of Golimumab in Japanese Patients With Moderately to Severely Active Ulcerative Colitis.P3completed144Janssen Pharmaceutical K.K.Mar 2013
NCT02186886PIMSPhysiological Intermolecular Modification Spectroscopy (PIMS) in Ulcerative Colitis With GolimumabP4unknown50Kliniken im Naturpark AltmuehltalJun 2014
NCT01295151SWITCHSWITCH Clinical Trial for Patients With Rheumatoid Arthritis Who Have Failed an Initial TNF-blocking Drug.P4completed122Julia BrownAug 2011
NCT02155335SMARTPreference for a Prefilled Syringe or Smartject™ Device for Delivering Golimumab in Participants Suffering From Moderate-to-severe Ulcerative Colitis (MK-8259-027)P4completed100Merck Sharp & Dohme LLCJul 2014
NCT01081717Golimumab Safety and Surveillance Program Using the Ingenix NHI Databasecompleted1,064Janssen Biotech, Inc.Apr 2009
NCT01668004GO-EASYThe Incidence of Extra-Articular Manifestations in Participants With Ankylosing Spondylitis Treated With Golimumab (MK-8259-012)P4completed101Merck Sharp & Dohme LLCSep 2012
NCT01715896A Study of Mavrilimumab Versus Anti Tumor Necrosis Factor in Subjects With Rheumatoid ArthritisP2completed215MedImmune LLCMar 2013
NCT00488631CNTO 148An Efficacy and Safety Study of Golimumab (CNTO 148) in Participants With Moderately to Severely Active Ulcerative ColitisP3completed1,228Janssen Research & Development, LLCSep 2007
NCT01453725GO-AHEADEffect of Golimumab in Participants With Active Axial Spondyloarthritis (P07642, MK-8259-006)P3completed198Merck Sharp & Dohme LLCFeb 2012
NCT01962974REGAINA Golimumab Phase 3b, Multicenter, Assessment of Intravenous Efficacy in Rheumatoid Arthritis Subjects Who Have Diminished Disease Control Despite Treatment With Infliximab (REMICADE®)P3terminated7Janssen Biotech, Inc.Oct 2013
NCT01718951Golimumab Versus Pamidronate for the Treatment of Axial Spondyloarthropathy: a 48-week TrialP4completed30Tuen Mun HospitalAug 2012
NCT01230827JIAA Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate (GO KIDS)P3terminated173Janssen Research & Development, LLCDec 2010
NCT01526174AIEDIntratympanic Injection for Autoimmune Inner Ear DiseaseP1/P2terminated16House Research InstituteMar 2012
NCT01004432ENBRELGolimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)P3completed433Janssen Biotech, Inc.Dec 2009
NCT00973479An Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate TherapyP3completed592Centocor, Inc.Sep 2009
NCT00955279SCA Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With SarcoidosisP2completed173Centocor, Inc.Nov 2009
NCT01248780Study of Subcutaneous Golimumab in Chinese Patients With Active Rheumatoid Arthritis Despite Methotrexate TherapyP3completed264Centocor, Inc.Sep 2010
NCT00264537A Study of the Safety and Efficacy of Golimumab in Subjects With Rheumatoid Arthritis That Are Methotrexate-naiveP3completed637Centocor, Inc.Dec 2005
NCT00299546CNTO 148A Study of the Safety and Efficacy of Golimumab (CNTO 148) in Subjects With Active Rheumatoid Arthritis Previously Treated With Biologic Anti-TNFa Agent(s)P3completed461Centocor, Inc.Feb 2006
NCT00264550GO-FORWARDAn Efficacy and Safety Study of Golimumab in Patients With Active Rheumatoid Arthritis Despite Methotrexate TherapyP3completed444Centocor, Inc.Dec 2005
NCT01248793Study of the Safety and Efficacy of Golimumab in Chinese Patients With Ankylosing SpondylitisP3completed213Centocor, Inc.Oct 2010
NCT00975130GO-MORESubcutaneous Golimumab (GLM) Plus DMARDs for Rheumatoid Arthritis, Followed by Intravenous/Subcutaneous GLM Strategy (P06129 AM2)P3completed3,366Merck Sharp & Dohme LLCSep 2009
NCT00265083A Study of the Safety and Efficacy of Golimumab in Subjects With Active Ankylosing SpondylitisP3completed356Centocor, Inc.Dec 2005
NCT00265096GO-REVEALA Study of the Safety and Efficacy of Golimumab in Patients With Active Psoriatic ArthritisP3completed407Centocor, Inc.Dec 2005
NCT01217814REGN88Effect of SAR153191 (REGN88) With Methotrexate in Patients With Active Rheumatoid Arthritis Who Failed TNF-α BlockersP2terminated16SanofiNov 2010
NCT01258777A Study of the Pharmacokinetics of Golimumab in Japanese and Caucasian Male SubjectsP1completed49Centocor, Inc.Oct 2010
NCT01288157A Study of the Pharmacokinetics of Golimumab in Chinese Male SubjectsP1completed24Centocor, Inc.Sep 2010
NCT00487539CNTO 148An Efficacy and Safety Study of Golimumab (CNTO 148) in Participants With Moderately to Severely Active Ulcerative ColitisP2/P3completed1,065Janssen Research & Development, LLCAug 2007
NCT00361335A Study of Safety and Effectiveness of Golimumab in Participants With Active Rheumatoid Arthritis Despite Methotrexate TherapyP3completed643Centocor, Inc.Sep 2006
NCT00488774An Efficacy and Safety Study of Golimumab in Participants With Ulcerative ColitisP2/P3terminated291Janssen Research & Development, LLCAug 2007
NCT01362153PKA Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of Golimumab in Patients With Rheumatoid Arthritis (RA)P1completed49Centocor, Inc.Dec 2007
NCT00675649A Clinical Trial Evaluating the Safety and Effectiveness of Golimumab in Patients With Severe, Persistent AsthmaP2withdrawn0Centocor, Inc.May 2008
NCT00207714An Efficacy and Safety Study of CNTO 148 Subcutaneous Injection Compared With Placebo in Patients With Active Rheumatoid ArthritisP2completed172Centocor, Inc.Nov 2003

Golimumab clinical trials: frequently asked questions

How many Golimumab clinical trials are there?
102 Golimumab clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 5 are actively recruiting participants. 63 are marked completed.
Are Golimumab clinical trials recruiting in 2026?
Yes — 5 Golimumab trials are actively recruiting in 2026, with 16 U.S. sites across 11 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Golimumab being studied for?
Golimumab is being studied for Rheumatoid Arthritis, Colitis, Ulcerative, Ulcerative Colitis, Arthritis, Rheumatoid, Ankylosing Spondylitis and 47 more. The trials are grouped by indication on this page.
What phase is Golimumab in?
Golimumab clinical trials span 22 Phase 4, 31 Phase 3, 17 Phase 2, 5 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Golimumab clinical trials?
The lead sponsor across the most Golimumab trials is Janssen Research & Development, LLC, with 54 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Golimumabas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

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Related pages on Hipa.ai:

Golimumab Clinical Trials (2026): 102 Studies | Hipa.ai