Foralumab Clinical Trials (2026): 10 Studies for Non-Active Secondary Progressive Multiple Sclerosis & Secondary Progressive Multiple Sclerosis

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

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10 Foralumab clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 9 indications (including Non-Active Secondary Progressive Multiple Sclerosis & Secondary Progressive Multiple Sclerosis) and 157 total planned enrollment. 4 Foralumab clinical trials are actively recruiting at 10 U.S. sites across 5 states. Most recent activity: NCT06868628 (Apr 2027).

Where to Participate: All Foralumab Trial Sites in the U.S. (10 sites across 5 states)

Every actively recruiting Foralumabtrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
CTYaleNorth Haven06473NCT06292923Map
MDJohns HopkinsBaltimore21287NCT06292923Map
MABrigham and Women's HospitalBoston02115NCT06292923Map
MABrigham and Women's HospitalBoston02115NCT06868628Map
MABrigham and Women's HospitalBoston02115NCT06890923Map
MACenter for Alzheimer Research and Treatment, Brigham and Women's HospitalBoston02115NCT06489548Map
MAUniversity of MassachusettsWorcester01655NCT06292923Map
NYUniversity of BuffaloBuffalo14202NCT06292923Map
NYCornell Weill Medical CenterNew York10021NCT06292923Map
PAThomas Jefferson University HospitalPhiladelphia19107NCT06292923Map

Foralumab clinical trials at a glance: phase × recruitment status

PhaserecruitingcompletedwithdrawnavailableTotal
P1123
P2426
N/A11

Recruiting Foralumab clinical trials (4)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT06868628MSAA Phase 2a Study of Foralumab Nasal in Patients With Multiple System Atrophy (MSA)P2Multiple System Atrophy5May 2025
NCT06489548Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's DiseaseP2Dementia16Sep 2025
NCT06890923TILS-022Nasal Foralumab in Patients With Non-Active Secondary Progressive Multiple SclerosisP2Non-Active Secondary Progressive Multiple Sclerosis55Mar 2025
NCT06292923A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis PatientsP2Secondary Progressive Multiple Sclerosis54Nov 2023

Foralumab clinical trials by indication

Non-Active Secondary Progressive Multiple Sclerosis (2)

NCTAcronymPhaseStatusTitle
NCT06890923TILS-022P2recruitingNasal Foralumab in Patients With Non-Active Secondary Progressive Multiple Sclerosis
NCT06802328N/AavailableIntermediate-Size Patient Population Expanded Access: Foralumab in Non-Active Secondary Progressive MS Patients

Dementia (1)

NCTAcronymPhaseStatusTitle
NCT06489548P2recruitingAssessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease

Multiple System Atrophy (1)

NCTAcronymPhaseStatusTitle
NCT06868628MSAP2recruitingA Phase 2a Study of Foralumab Nasal in Patients With Multiple System Atrophy (MSA)

Secondary Progressive Multiple Sclerosis (1)

NCTAcronymPhaseStatusTitle
NCT06292923P2recruitingA Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients

Crohn's Disease (1)

NCTAcronymPhaseStatusTitle
NCT05028946P1withdrawnA Study of Oral Foralumab in Participants With Moderate to Severely Active Crohn's Disease

Covid19 (1)

NCTAcronymPhaseStatusTitle
NCT04983446P2withdrawnIn-patient COVID-19 Study of Intranasal Foralumab

Primary Progressive Multiple Sclerosis (1)

NCTAcronymPhaseStatusTitle
NCT05029609P1withdrawnPhase 1b Multiple Ascending Dose Study of Foralumab in Primary and Secondary Progressive MS

Safety (1)

NCTAcronymPhaseStatusTitle
NCT06879067P1completedSafety, Tolerability and Immune Effects of the Nasal Foralumab in Healthy Human Volunteers

NASH - Nonalcoholic Steatohepatitis (1)

NCTAcronymPhaseStatusTitle
NCT03291249P2withdrawnAssessment of the Safety of Foralumab, an Oral Anti-CD3 Antibody, in Patients With NASH and T2DM

Foralumab pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

AcronymNCTPhaseStatusIndicationEnrollmentPubMed
MSANCT06868628P2recruitingMultiple System Atrophy5PMID 35445419
TILS-022NCT06890923P2recruitingNon-Active Secondary Progressive Multiple Sclerosis55

Terminated and withdrawn Foralumab trials (4)

Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.

All Foralumab trials (10)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT06868628MSAA Phase 2a Study of Foralumab Nasal in Patients With Multiple System Atrophy (MSA)P2recruiting5Tiziana Life Sciences LTDMay 2025
NCT06489548Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's DiseaseP2recruiting16Brigham and Women's HospitalSep 2025
NCT06890923TILS-022Nasal Foralumab in Patients With Non-Active Secondary Progressive Multiple SclerosisP2recruiting55Tiziana Life Sciences LTDMar 2025
NCT06292923A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis PatientsP2recruiting54Tiziana Life Sciences LTDNov 2023
NCT06802328Intermediate-Size Patient Population Expanded Access: Foralumab in Non-Active Secondary Progressive MS Patientsavailable0Tiziana Life Sciences LTD
NCT05028946A Study of Oral Foralumab in Participants With Moderate to Severely Active Crohn's DiseaseP1withdrawn0Tiziana Life Sciences LTDMay 2022
NCT05029609Phase 1b Multiple Ascending Dose Study of Foralumab in Primary and Secondary Progressive MSP1withdrawn0Tiziana Life Sciences LTDOct 2021
NCT04983446In-patient COVID-19 Study of Intranasal ForalumabP2withdrawn0Tiziana Life Sciences LTDApr 2022
NCT06879067Safety, Tolerability and Immune Effects of the Nasal Foralumab in Healthy Human VolunteersP1completed27Tiziana Life Sciences LTDNov 2018
NCT03291249Assessment of the Safety of Foralumab, an Oral Anti-CD3 Antibody, in Patients With NASH and T2DMP2withdrawn0Tiziana Life Sciences LTDDec 2017

Foralumab clinical trials: frequently asked questions

How many Foralumab clinical trials are there?
10 Foralumab clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 4 are actively recruiting participants. 1 is marked completed.
Are Foralumab clinical trials recruiting in 2026?
Yes — 4 Foralumab trials are actively recruiting in 2026, with 10 U.S. sites across 5 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Foralumab being studied for?
Foralumab is being studied for Non-Active Secondary Progressive Multiple Sclerosis, Secondary Progressive Multiple Sclerosis, COVID-19 Respiratory Infection, Covid19, Crohn's Disease and 12 more. The trials are grouped by indication on this page.
What phase is Foralumab in?
Foralumab clinical trials span 6 Phase 2, 3 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Foralumab clinical trials?
The lead sponsor across the most Foralumab trials is Tiziana Life Sciences LTD, with 1 additional lead sponsor listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Foralumabas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

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