EDG-7500 Clinical Trials (2026): 6 Studies for Healthy Adult Participants & Healthy Subjects

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

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6 EDG-7500 clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 6 indications (including Healthy Adult Participants & Healthy Subjects) and 285 total planned enrollment. 2 EDG-7500 clinical trials are actively recruiting at 2 U.S. sites across 1 state. Most recent activity: NCT06347159 (Dec 2026).

Where to Participate: All EDG-7500 Trial Sites in the U.S. (2 sites across 1 state)

Every actively recruiting EDG-7500trial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
FLThe University of Miami Division of Clinical PharmacologyMiami33136NCT07324616Map
FLOrlando Clinical Research CenterOrlando32809NCT07324616Map

EDG-7500 clinical trials at a glance: phase × recruitment status

Phaserecruitingactive not recruitingcompletednot yet recruitingTotal
P11315
P211

Recruiting EDG-7500 clinical trials (2)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT07456059A Study to Evaluate EDG-7500 in Caucasian and Japanese AdultsP1Healthy Adult Participants24Mar 2026
NCT07324616A Study to Evaluate EDG-7500 in Adults With Hepatic ImpairmentP1Hepatic Impairment (HI)32Jan 2026

EDG-7500 clinical trials by indication

Healthy Adult Participants (1)

NCTAcronymPhaseStatusTitle
NCT07456059P1not yet recruitingA Study to Evaluate EDG-7500 in Caucasian and Japanese Adults

Hepatic Impairment (HI) (1)

NCTAcronymPhaseStatusTitle
NCT07324616P1recruitingA Study to Evaluate EDG-7500 in Adults With Hepatic Impairment

Renal Impairments (1)

NCTAcronymPhaseStatusTitle
NCT07034768P1completedA Study to Evaluate EDG-7500 in People With Renal Impairment

Healthy Volunteer (1)

NCTAcronymPhaseStatusTitle
NCT06738836P1completedA Study to Evaluate the Absorption, Metabolism, And Excretion Of Orally Administered [14C]-EDG-7500

Hypertrophic Cardiomyopathy (1)

NCTAcronymPhaseStatusTitle
NCT06347159CIRRUS-HCMP2active not recruitingA Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM)

Healthy Subjects (1)

NCTAcronymPhaseStatusTitle
NCT06011317P1completedA Study of EDG-7500 in Healthy Adults

EDG-7500 pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

AcronymNCTPhaseStatusIndicationEnrollmentPubMed
CIRRUS-HCMNCT06347159P2active not recruitingHypertrophic Cardiomyopathy100

All EDG-7500 trials (6)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT06347159CIRRUS-HCMA Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM)P2active not recruiting100Edgewise Therapeutics, Inc.Apr 2024
NCT07456059A Study to Evaluate EDG-7500 in Caucasian and Japanese AdultsP1not yet recruiting24Edgewise Therapeutics, Inc.Mar 2026
NCT07324616A Study to Evaluate EDG-7500 in Adults With Hepatic ImpairmentP1recruiting32Edgewise Therapeutics, Inc.Jan 2026
NCT07034768A Study to Evaluate EDG-7500 in People With Renal ImpairmentP1completed37Edgewise Therapeutics, Inc.Jul 2025
NCT06738836A Study to Evaluate the Absorption, Metabolism, And Excretion Of Orally Administered [14C]-EDG-7500P1completed8Edgewise Therapeutics, Inc.Dec 2024
NCT06011317A Study of EDG-7500 in Healthy AdultsP1completed84Edgewise Therapeutics, Inc.Aug 2023

EDG-7500 clinical trials: frequently asked questions

How many EDG-7500 clinical trials are there?
6 EDG-7500 clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 1 is actively recruiting participants. 3 are marked completed.
Are EDG-7500 clinical trials recruiting in 2026?
Yes — 1 EDG-7500 trial is actively recruiting in 2026, with 2 U.S. sites across 1 state. See the recruiting trials and the per-state site list further down this page.
What conditions is EDG-7500 being studied for?
EDG-7500 is being studied for Healthy Adult Participants, Healthy Subjects, Healthy Volunteer, Hepatic Impairment (HI), Hypertrophic Cardiomyopathy and 1 more. The trials are grouped by indication on this page.
What phase is EDG-7500 in?
EDG-7500 clinical trials span 1 Phase 2, 5 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors EDG-7500 clinical trials?
The lead sponsor across the most EDG-7500 trials is Edgewise Therapeutics, Inc.. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming EDG-7500as an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

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