Dotinurad Clinical Trials (2026): 7 Studies for Gout & Healthy Volunteers
Hipa.ai Research · Source: ClinicalTrials.gov / AACT
Synced daily from ClinicalTrials.gov via AACT. Last sync: .
7 Dotinurad clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 4 indications (including Gout & Healthy Volunteers) and 1,697 total planned enrollment. 3 Phase 3 Dotinurad trials and 1 Phase 2, 1 Phase 4 are listed. 4 Dotinurad clinical trials are actively recruiting at 160 U.S. sites across 25 states. Most recent activity: NCT06834230 (Mar 2030).
Where to Participate: All Dotinurad Trial Sites in the U.S. (160 sites across 25 states)
Every actively recruiting Dotinuradtrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.
| State | Facility | City | Trial | Map |
|---|---|---|---|---|
| AL | The Kirklin Clinic of University of Alabama Birmingham Hospital | Birmingham35233 | NCT07089888 | Map |
| AL | University of Alabama at Birmingham | Birmingham35233 | NCT07089875 | Map |
| AL | G & L Research | Foley36535 | NCT07089888 | Map |
| AZ | Arizona Arthritis & Rheumatology Associates (AARA) - Gilbert | Gilbert85297 | NCT07089875 | Map |
| AZ | Arizona Arthritis & Rheumatology Associates (AARA) - Gilbert | Gilbert85297 | NCT07089888 | Map |
| AZ | Arizona Arthritis & Rheumatology Associates (AARA) - Glendale | Glendale85306 | NCT07089875 | Map |
| AZ | Arizona Arthritis & Rheumatology Associates (AARA) - Glendale | Glendale85306 | NCT07089888 | Map |
| AZ | Arizona Arthritis & Rheumatology Associates (AARA) - Mesa | Mesa85110 | NCT07089875 | Map |
| AZ | Arizona Arthritis & Rheumatology Associates (AARA) - Mesa | Mesa85210 | NCT07089888 | Map |
| AZ | Del Sol Research Management - Tucson | Tucson85715 | NCT07089875 | Map |
| AZ | Del Sol Research Management - Tucson East | Tucson85715 | NCT07089875 | Map |
| AZ | Del Sol Research Management - Tucson East | Tucson85715 | NCT07089888 | Map |
| CA | Medvin Clinical Research - Covina | Covina91722 | NCT07089875 | Map |
| CA | Medvin Clinical Research - Covina | Covina91722 | NCT07089888 | Map |
| CA | West Coast Research | Dublin94568 | NCT07089875 | Map |
| CA | West Coast Research | Dublin94568 | NCT07089888 | Map |
| CA | Amicis Research Center | Granada Hills91344 | NCT07535034 | Map |
| CA | Infinity Clinical Research | Norco92860 | NCT07089875 | Map |
| CA | Infinity Clinical Research | Norco92860 | NCT07089888 | Map |
| CA | Amicis Research Center - Balboa | Northridge91324 | NCT07089875 | Map |
| CA | Amicis Research Center - Balboa | Northridge91324 | NCT07089888 | Map |
| CA | Cure Clinical Research, LLC | Orange92866 | NCT07089888 | Map |
| CA | Velocity Clinical Research - San Bernardino | San Bernardino92408 | NCT07089875 | Map |
| CA | Velocity Clinical Research - San Bernardino | San Bernardino92408 | NCT07089888 | Map |
| CA | Acclaim Clinical Research, Inc. | San Diego92120 | NCT07089875 | Map |
| CA | Acclaim Clinical Research, Inc. | San Diego92120 | NCT07089888 | Map |
| CA | East Bay Rheumatology Medical Group | San Leandro94578 | NCT07089875 | Map |
| CA | East Bay Rheumatology Medical Group | San Leandro94578 | NCT07089888 | Map |
| CA | BTC Network - Encompass Clinical Research | Spring Valley91978 | NCT07089875 | Map |
| CA | BTC Network - Encompass Clinical Research | Spring Valley91978 | NCT07089888 | Map |
| CA | Cohen Medical Center | Thousand Oaks91360 | NCT07535034 | Map |
| CA | Cohen Medical Centers | Thousand Oaks91360-3967 | NCT07089875 | Map |
| CA | Cohen Medical Centers | Thousand Oaks91360-3967 | NCT07089888 | Map |
| CA | Medvin Clinical Research - Tujunga | Tujunga91042 | NCT07089875 | Map |
| CA | Medvin Clinical Research - Tujunga | Tujunga91042 | NCT07089888 | Map |
| CO | Denver Arthritis Clinic - Lowry | Denver80230 | NCT07089875 | Map |
| CO | Denver Arthritis Clinic - Lowry | Denver80230 | NCT07089888 | Map |
| FL | Bradenton Research Center | Bradenton34205 | NCT07089875 | Map |
| FL | Bradenton Research Center | Bradenton34205 | NCT07089888 | Map |
| FL | Herco Medical and Research Center, Inc | Coral Gables33134 | NCT07089875 | Map |
| FL | Herco Medical and Research Center, Inc | Coral Gables33134 | NCT07089888 | Map |
| FL | Omega Research Group | DeBary32713 | NCT07535034 | Map |
| FL | Best Quality Research | Hialeah33016 | NCT07089875 | Map |
| FL | Best Quality Research | Hialeah33016 | NCT07089888 | Map |
| FL | New Generation of Medical Research | Hialeah32016 | NCT07089875 | Map |
| FL | New Generation of Medical Research | Hialeah32016 | NCT07089888 | Map |
| FL | Health Awareness Inc | Jupiter33458 | NCT07089875 | Map |
| FL | Health Awareness Inc | Jupiter33458 | NCT07089888 | Map |
| FL | Clinical Research of Center Florida | Lakeland33805 | NCT07089875 | Map |
| FL | Clinical Research of Center Florida | Lakeland33805 | NCT07089888 | Map |
| FL | Clinical Research of Central Florida | Lakeland33805 | NCT07535034 | Map |
| FL | D&H Pompano Research Center | Margate33063 | NCT07089888 | Map |
| FL | Anchor Medical Research | Miami33176 | NCT07535034 | Map |
| FL | Anchor Medical Research, LLC | Miami33176 | NCT07089875 | Map |
| FL | Anchor Medical Research, LLC | Miami33176 | NCT07089888 | Map |
| FL | Panax Clinical Research | Miami33014 | NCT07535034 | Map |
| FL | Well Pharma Medical Research | Miami33173 | NCT07089888 | Map |
| FL | Panax Clinical Research | Miami Lakes33014 | NCT07089875 | Map |
| FL | Panax Clinical Research | Miami Lakes33014 | NCT07089888 | Map |
| FL | Omega Research DeBary | Orlando32808 | NCT07089875 | Map |
| FL | Omega Research DeBary | Orlando32808 | NCT07089888 | Map |
| FL | D&H Pompano Research Center | Pompano Beach33064 | NCT07089875 | Map |
| FL | Clinical Research Trials of Florida | Tampa33607 | NCT07089875 | Map |
| FL | Clinical Research Trials of Florida | Tampa33607 | NCT07089888 | Map |
| FL | Conquest Research - Winter Park | Winter Park32789 | NCT07089875 | Map |
| FL | Conquest Research - Winter Park | Winter Park32789 | NCT07089888 | Map |
| IL | Chicago Clinical Research Institute, Inc. (CCRII) | Chicago60607 | NCT07089875 | Map |
| IL | Chicago Clinical Research Institute, Inc. (CCRII) | Chicago60607 | NCT07089888 | Map |
| IL | Flourish Chicago - Ravenswood (Great Lakes Clinical Trials) | Chicago60640 | NCT07089875 | Map |
| IL | Flourish Chicago - Ravenswood (Great Lakes Clinical Trials) | Chicago60640 | NCT07089888 | Map |
| IL | Healthcare Research Network - Tinley Park | Flossmoor60402 | NCT07089875 | Map |
| IN | Investigators Research Group | Brownsburg46112 | NCT07089875 | Map |
| IN | MediSphere Medical Research Center, LLC | Evansville47714 | NCT07089875 | Map |
| IN | MediSphere Medical Research Center, LLC - East | Evansville47714 | NCT07089888 | Map |
| KS | Delricht Research - Concierge And Direct Primary Care | Overland Park66223 | NCT07089875 | Map |
| KS | Delricht Research - Concierge And Direct Primary Care | Overland Park66223 | NCT07089888 | Map |
| KY | DelRicht Research - Louisville (Derby City DPC) | Louisville40205 | NCT07089875 | Map |
| KY | DelRicht Research - Louisville (Derby City DPC) | Louisville40205 | NCT07089888 | Map |
| LA | Tandem Clinical Research - Metairie Clinic | Metairie70006 | NCT07089875 | Map |
| LA | Tandem Clinical Research - Metairie Clinic | Metairie70006 | NCT07089888 | Map |
| LA | DelRicht Research - LCMC Health Urgent Care - Lakeview | New Orleans70124 | NCT07089875 | Map |
| LA | DelRicht Research - LCMC Health Urgent Care - Lakeview | New Orleans70124 | NCT07089888 | Map |
| LA | DelRicht Research - Prairieville | Prairieville70769 | NCT07089875 | Map |
| LA | DelRicht Research - Prairieville | Prairieville70769 | NCT07089888 | Map |
| MD | MD Medical Research | Oxon Hill20745 | NCT07535034 | Map |
| MD | MD Medical Research - Oxon Hill | Oxon Hill20745 | NCT07089875 | Map |
| MD | MD Medical Research - Oxon Hill | Oxon Hill20745 | NCT07089888 | Map |
| MA | MedVadis Research | Waltham02451 | NCT07089875 | Map |
| MA | MedVadis Research | Waltham02451 | NCT07089888 | Map |
| MI | A. Alfred Taubman Health Care Center | Ann Arbor48109 | NCT07089888 | Map |
| MI | Michigan Medicine - University of Michigan | Ann Arbor48109-5000 | NCT07089875 | Map |
| MI | Clinical Research Institute of Michigan | Saint Clair Shores48081 | NCT07535034 | Map |
| MI | Clinical Research Institute of Michigan - St. Clair Shores | Saint Clair Shores48081 | NCT07089875 | Map |
| MI | Clinical Research Institute of Michigan - St. Clair Shores | Saint Clair Shores48081 | NCT07089888 | Map |
| MI | Revival Research Institute | Sterling Heights48313 | NCT07535034 | Map |
| MI | Revival Research Institute - Sterling Heights | Sterling Heights48313 | NCT07089888 | Map |
| MI | Revive Research Institute - Sterling Heights | Sterling Heights48313 | NCT07089875 | Map |
| MI | Oakland Medical Center | Troy48085 | NCT07089875 | Map |
| MI | Oakland Medical Center | Troy48085 | NCT07089888 | Map |
| MO | DelRicht Research - Town and Country | Town and Country63017 | NCT07089875 | Map |
| MO | DelRicht Research - Town and Country | Town and Country63017 | NCT07089888 | Map |
| NV | Las Vegas Clinical Trials | Las Vegas89030 | NCT07535034 | Map |
| NV | Las Vegas Clinical Trials | North Las Vegas89030 | NCT07089875 | Map |
| NV | Las Vegas Clinical Trials | North Las Vegas89030 | NCT07089888 | Map |
| NJ | Sahni Rheumatology & Therapy | West Long Branch07764 | NCT07089888 | Map |
| NY | Ellipsis Research Group | Brooklyn11215 | NCT07089875 | Map |
| NY | Ellipsis Research Group | Brooklyn11215 | NCT07089888 | Map |
| NY | Ellipsis Research Group | Brooklyn11215 | NCT07535034 | Map |
| NY | Drug Trials America | Hartsdale10530 | NCT07535034 | Map |
| NY | NYU Langone Health | New York10016 | NCT07089875 | Map |
| NY | NYU Langone Health | New York10016 | NCT07089888 | Map |
| NC | DelRicht Research | Charlotte28210 | NCT07089875 | Map |
| NC | DelRicht Research | Charlotte28210 | NCT07089888 | Map |
| NC | Triad Clinical Trials | Greensboro27410 | NCT07089888 | Map |
| NC | Carteret Medical Group LLC | Morehead City28557 | NCT07089875 | Map |
| NC | Shelby Clinical Research | Shelby28150 | NCT07535034 | Map |
| NC | Shelby Clinical Research, LLC - North Carolina | Shelby28150 | NCT07089875 | Map |
| NC | Shelby Clinical Research, LLC - North Carolina | Shelby28150 | NCT07089888 | Map |
| OH | Hometown Urgent Care and Research - Dayton | Dayton45424 | NCT07089875 | Map |
| OH | Hometown Urgent Care and Research - Dayton | Dayton45424 | NCT07089888 | Map |
| PA | Altoona Center for Clinical Research | Duncansville16635 | NCT07089875 | Map |
| SC | Coastal Carolina Research Center - Main | North Charleston29405 | NCT07089875 | Map |
| SC | Coastal Carolina Research Center - Main | North Charleston29405 | NCT07089888 | Map |
| SD | Health Concepts | Rapid City57702 | NCT07089875 | Map |
| SD | Health Concepts | Rapid City57702 | NCT07089888 | Map |
| TX | Arthritis & Osteoporosis Center of Coastal Bend | Corpus Christi78415 | NCT07089888 | Map |
| TX | Zenos Clinical Research | Dallas75230 | NCT07089875 | Map |
| TX | Zenos Clinical Research | Dallas75230 | NCT07089888 | Map |
| TX | Zenos Clinical Research | Dallas75230 | NCT07535034 | Map |
| TX | Lone Star Arthritis & Rheumatology Associates - Denton | Denton76205 | NCT07089875 | Map |
| TX | Lone Star Arthritis & Rheumatology Associates - Denton | Denton76205 | NCT07089888 | Map |
| TX | Epic Medical Research | DeSoto75115 | NCT07535034 | Map |
| TX | Epic Medical Research - DeSoto | DeSoto75115 | NCT07089875 | Map |
| TX | Epic Medical Research - DeSoto | DeSoto75115 | NCT07089888 | Map |
| TX | Pioneeer Research Solutions | Houston77099 | NCT07089888 | Map |
| TX | Pioneer Research Solutions | Houston77099 | NCT07089875 | Map |
| TX | Pioneer Research Solutions | Houston77479 | NCT07535034 | Map |
| TX | Prolato Clinical Research Center | Houston77027 | NCT07089875 | Map |
| TX | Prolato Clinical Research Center | Houston77027 | NCT07089888 | Map |
| TX | Epic Medical Research - Hurst | Hurst76054 | NCT07089888 | Map |
| TX | R & H Clinical Research - South Fry Road | Katy77450 | NCT07089888 | Map |
| TX | R & H Clinical Research - Westborough Drive | Katy77449 | NCT07089875 | Map |
| TX | Premise Clinical Research Center | Lancaster75146 | NCT07089888 | Map |
| TX | Alliance Clinical Lewisville (Epic Clinical Research) | Lewisville75057 | NCT07089875 | Map |
| TX | Alliance Clinical Lewisville (Epic Clinical Research) | Lewisville75057 | NCT07089888 | Map |
| TX | Southwest Rheumatology Research | Mesquite75150 | NCT07089875 | Map |
| TX | Southwest Rheumatology Research | Mesquite75150 | NCT07089888 | Map |
| TX | Discovery Clinical Trials | San Antonio78229 | NCT07089875 | Map |
| TX | Discovery Clinical Trials | San Antonio78229 | NCT07089888 | Map |
| TX | ERG - Endeavor Clinical Trials | San Antonio78240 | NCT07089875 | Map |
| TX | ERG - Endeavor Clinical Trials | San Antonio78240 | NCT07089888 | Map |
| TX | Epic Medical Research - San Marcos | San Marcos78666 | NCT07089888 | Map |
| TX | Siena Research Network | Sugar Land77479 | NCT07089888 | Map |
| TX | DM Clinical Research | Tomball77375 | NCT07535034 | Map |
| TX | DM Clinical Research - Tomball - Multiple Specialties | Tomball77375 | NCT07089875 | Map |
| TX | DM Clinical Research - Tomball - Multiple Specialties | Tomball77375 | NCT07089888 | Map |
| UT | Rio Clinical Trials - Corporate Office | Ogden84404 | NCT07089888 | Map |
| VA | Charlottesville Medical Research | Charlottesville22911 | NCT07089875 | Map |
| VA | Charlottesville Medical Research | Charlottesville22911 | NCT07089888 | Map |
| VA | Gershon Pain Specialists | Virginia Beach23454 | NCT07089888 | Map |
Dotinurad clinical trials at a glance: phase × recruitment status
| Phase | recruiting | completed | Total |
|---|---|---|---|
| P1 | 1 | 1 | |
| P1/P2 | 1 | 1 | |
| P2 | 1 | 1 | |
| P3 | 2 | 1 | 3 |
| P4 | 1 | 1 |
Recruiting Dotinurad clinical trials (4)
Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).
| NCT ID | Title | Phase | Indication | Enrollment | Started |
|---|---|---|---|---|---|
| NCT06834230 | DIANA-NEXTEffect of Dotinurad in Hyperuricemia With Hypertension | P4 | Hyperuricemia or Gout | 360 | Mar 2025 |
| NCT07089888 | A Study of Dotinurad Versus Allopurinol in Tophaceous Gout | P3 | Tophaceous Gout | 250 | Aug 2025 |
| NCT07089875 | A Study of Dotinurad Versus Allopurinol in Participants With Gout | P3 | Gout | 500 | Aug 2025 |
| NCT07535034 | XOIA Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants | P2 | Gout | 90 | May 2026 |
Dotinurad clinical trials by indication
Gout (4)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07089875 | — | P3 | recruiting | A Study of Dotinurad Versus Allopurinol in Participants With Gout |
| NCT07535034 | XOI | P2 | recruiting | A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants |
| NCT06056570 | — | P1/P2 | completed | Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients With Hyperuricemia |
| NCT05007392 | — | P3 | completed | A Study to Evaluate Efficacy of Dotinurad and Febuxostat for the Treatment of Participants With Gout |
Tophaceous Gout (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07089888 | — | P3 | recruiting | A Study of Dotinurad Versus Allopurinol in Tophaceous Gout |
Hyperuricemia or Gout (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06834230 | DIANA-NEXT | P4 | recruiting | Effect of Dotinurad in Hyperuricemia With Hypertension |
Healthy Volunteers (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT05278676 | — | P1 | completed | A Single and Multiple Dose Study of Dotinurad in Chinese Healthy Participants |
Dotinurad pivotal trial highlights (Phase 2/3/4)
Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.
| Acronym | NCT | Phase | Status | Indication | Enrollment | PubMed |
|---|---|---|---|---|---|---|
| DIANA-NEXT | NCT06834230 | P4 | recruiting | Hyperuricemia or Gout | 360 | — |
| XOI | NCT07535034 | P2 | recruiting | Gout | 90 | — |
All Dotinurad trials (7)
Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.
| NCT ID | Acronym | Title | Phase | Status | Enrollment | Sponsor | Started |
|---|---|---|---|---|---|---|---|
| NCT06834230 | DIANA-NEXT | Effect of Dotinurad in Hyperuricemia With Hypertension | P4 | recruiting | 360 | Saga University | Mar 2025 |
| NCT07089888 | A Study of Dotinurad Versus Allopurinol in Tophaceous Gout | P3 | recruiting | 250 | Crystalys Therapeutics | Aug 2025 | |
| NCT07089875 | A Study of Dotinurad Versus Allopurinol in Participants With Gout | P3 | recruiting | 500 | Crystalys Therapeutics | Aug 2025 | |
| NCT07535034 | XOI | A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants | P2 | recruiting | 90 | Crystalys Therapeutics | May 2026 |
| NCT06056570 | Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients With Hyperuricemia | P1/P2 | completed | 20 | Urica Therapeutics Inc. | Oct 2023 | |
| NCT05007392 | A Study to Evaluate Efficacy of Dotinurad and Febuxostat for the Treatment of Participants With Gout | P3 | completed | 451 | Eisai Co., Ltd. | Dec 2021 | |
| NCT05278676 | A Single and Multiple Dose Study of Dotinurad in Chinese Healthy Participants | P1 | completed | 26 | Eisai Co., Ltd. | Jul 2022 |
Dotinurad clinical trials: frequently asked questions
- How many Dotinurad clinical trials are there?
- 7 Dotinurad clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 4 are actively recruiting participants. 3 are marked completed.
- Are Dotinurad clinical trials recruiting in 2026?
- Yes — 4 Dotinurad trials are actively recruiting in 2026, with 160 U.S. sites across 25 states. See the recruiting trials and the per-state site list further down this page.
- What conditions is Dotinurad being studied for?
- Dotinurad is being studied for Gout, Healthy Volunteers, Hypertension, Hyperuricemia, Hyperuricemia or Gout and 1 more. The trials are grouped by indication on this page.
- What phase is Dotinurad in?
- Dotinurad clinical trials span 1 Phase 4, 3 Phase 3, 1 Phase 2, 1 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
- Who sponsors Dotinurad clinical trials?
- The lead sponsor across the most Dotinurad trials is Crystalys Therapeutics, with 3 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.
Sources and methodology
Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Dotinuradas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.
Last refreshed .
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