Carisbamate Evidence: Trial Results and Peer-Reviewed Publications

Hipa.ai Research · Source: PubMed & ClinicalTrials.gov / AACT · Last updated: May 26, 2026

The clinical evidence base for Carisbamate comprises 3 peer-reviewed publications across 3 journals, 0 pivotal-trial primary-outcome rows reported to ClinicalTrials.gov, spanning indications including Seizures, and Essential Tremor. Most recent publication: Carisbamate add-on therapy for drug-resistant focal epilepsy., Cochrane Database Syst Rev, 2022.

Top peer-reviewed publications

Curated set of pivotal-trial result papers and recent publications in high-tier journals.

Carisbamate add-on therapy for drug-resistant focal epilepsy.
Lu C, Zheng J, Cao Y, et al. · Cochrane Database Syst Rev · 2022
PubMed: PMID 34870321 · NCT00740623 · Seizures
A randomized, double-blind, placebo-controlled study of the efficacy, safety, and tolerability of adjunctive carisbamate treatment in patients with partial-onset seizures.
Halford JJ, Ben-Menachem E, Kwan P, et al. · Epilepsia · 2011
PubMed: PMID 21320109 · NCT00740623 · Seizures
Carisbamate in essential tremor: brief report of a proof of concept study.
Elble RJ, Biondi DM, Ascher S, et al. · Mov Disord · 2010
PubMed: PMID 20201005 · NCT00524056 · Essential Tremor

Publications by year

2010–2022: 3 publications.

2010

2011

2022

Publications by indication

Seizures (2)

Carisbamate add-on therapy for drug-resistant focal epilepsy.
Cochrane Database Syst Rev · 2022 · PMID 34870321 · NCT00740623
A randomized, double-blind, placebo-controlled study of the efficacy, safety, and tolerability of adjunctive carisbamate treatment in patients with partial-onset seizures.
Epilepsia · 2011 · PMID 21320109 · NCT00740623

Essential Tremor (1)

Carisbamate in essential tremor: brief report of a proof of concept study.
Mov Disord · 2010 · PMID 20201005 · NCT00524056

Publications by journal

Cochrane Database Syst Rev1 paper
Epilepsia1 paper
Mov Disord1 paper

All Carisbamate publications (3)

2022 (1 paper)

Carisbamate add-on therapy for drug-resistant focal epilepsy.
Lu C, Zheng J, Cao Y, et al. · Cochrane Database Syst Rev · 2022 · Derived
PubMed: PMID 34870321 · NCT00740623 · Seizures

2011 (1 paper)

A randomized, double-blind, placebo-controlled study of the efficacy, safety, and tolerability of adjunctive carisbamate treatment in patients with partial-onset seizures.
Halford JJ, Ben-Menachem E, Kwan P, et al. · Epilepsia · 2011 · Derived
PubMed: PMID 21320109 · NCT00740623 · Seizures

2010 (1 paper)

Carisbamate in essential tremor: brief report of a proof of concept study.
Elble RJ, Biondi DM, Ascher S, et al. · Mov Disord · 2010 · Derived
PubMed: PMID 20201005 · NCT00524056 · Essential Tremor

Sources and methodology

Publications: ctgov.study_references (PubMed PMIDs auto-attached by ClinicalTrials.gov to each trial), reference types RESULT, DERIVED, and BACKGROUND.
Per-arm outcome values: ctgov.outcome_measurements joined to ctgov.design_outcomes where outcome_type = 'PRIMARY', restricted to phase PHASE3 and PHASE2/PHASE3.
Publication metadata (title, journal, year, authors): PubMed E-utilities efetch.fcgi
Data freshness: Tue, 26 May 2026 18:06:34 GMT.

This page summarizes published evidence for general reference and does not constitute medical advice. For clinical decisions, consult the linked primary publications and your healthcare provider. Data sourced from PubMed and the ClinicalTrials.gov / AACT database maintained by the Clinical Trials Transformation Initiative (CTTI).