How many Baxdrostat clinical trials are there?

16 Baxdrostat clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 4 are actively recruiting participants. 11 are marked completed.

Are Baxdrostat clinical trials recruiting in 2026?

Yes — 4 Baxdrostat trials are actively recruiting in 2026, with 285 U.S. sites across 41 states. See the recruiting trials and the per-state site list further down this page.

What conditions is Baxdrostat being studied for?

Baxdrostat is being studied for Hypertension, Healthy Participants, Chronic Kidney Disease and Hypertension, Resistant Hypertension, Uncontrolled Hypertension and 2 more. The trials are grouped by indication on this page.

What phase is Baxdrostat in?

Baxdrostat clinical trials span 7 Phase 3, 2 Phase 2, 7 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.

Who sponsors Baxdrostat clinical trials?

The lead sponsor across the most Baxdrostat trials is AstraZeneca. Each trial row links to the full study detail page including sponsor information.

Baxdrostat Clinical Trials (2026): 16 Studies for Hypertension & Healthy Participants

Creator: Hipa.ai Research
Published: 2026-05-07T20:08:27.070Z

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: June 12, 2026.

16 Baxdrostat clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 7 indications (including Hypertension & Healthy Participants) and 20,857 total planned enrollment. 7 Phase 3 Baxdrostat trials and 2 Phase 2 are listed. 4 Baxdrostat clinical trials are actively recruiting at 285 U.S. sites across 41 states. Most recent activity: NCT06742723 (Dec 2029).

Where to Participate: All Baxdrostat Trial Sites in the U.S. (285 sites across 41 states)

Every actively recruiting Baxdrostattrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

State	Facility	City	Trial	Map
AL	Research Site	Birmingham35205	NCT06677060	Map
AL	Research Site	Centreville35042	NCT06677060	Map
AL	Research Site	Fairhope36532	NCT06677060	Map
AL	Research Site	Fairhope36532	NCT06742723	Map
AL	Research Site	Huntsville35801	NCT06677060	Map
AL	Research Site	Mobile36608	NCT06677060	Map
AL	Research Site	Vestavia Hills35216	NCT06677060	Map
AZ	Research Site	Gilbert85296	NCT06677060	Map
AZ	Research Site	Glendale85308	NCT06677060	Map
AZ	Research Site	Surprise85374	NCT06742723	Map
AZ	Research Site	Surprise85374	NCT07222917	Map
AZ	Research Site	Tempe85283	NCT06677060	Map
AZ	Research Site	Tucson85712	NCT06677060	Map
AZ	Research Site	Tucson85710	NCT06742723	Map
CA	Research Site	Beverly Hills90211	NCT06742723	Map
CA	Research Site	Concord94520	NCT06742723	Map
CA	Research Site	Fremont94538	NCT06742723	Map
CA	Research Site	Fullerton92835	NCT06742723	Map
CA	Research Site	Huntington Beach92648	NCT06677060	Map
CA	Research Site	Inglewood90301	NCT06677060	Map
CA	Research Site	La Jolla92037	NCT06677060	Map
CA	Research Site	Lincoln95648	NCT06677060	Map
CA	Research Site	Loma Linda92357	NCT06677060	Map
CA	Research Site	Los Alamitos90720	NCT06742723	Map
CA	Research Site	Los Angeles90035	NCT06677060	Map
CA	Research Site	Los Angeles90073	NCT06742723	Map
CA	Research Site	Sacramento95841	NCT06677060	Map
CA	Research Site	San Diego92120	NCT06677060	Map
CA	Research Site	San Dimas91773	NCT06677060	Map
CA	Research Site	Santa Maria93454	NCT06677060	Map
CA	Research Site	Tarzana91356	NCT06742723	Map
CA	Research Site	Thousand Oaks91360	NCT06677060	Map
CO	Research Site	Arvada80002	NCT06742723	Map
CO	Research Site	Aurora80012	NCT06677060	Map
CO	Research Site	Englewood80110	NCT06677060	Map
CT	Research Site	Bridgeport06606	NCT06677060	Map
CT	Research Site	New Britain06051	NCT06742723	Map
CT	Research Site	Stamford06905	NCT06677060	Map
CT	Research Site	Waterbury06708	NCT06677060	Map
DC	Research Site	Washington D.C.20037	NCT06742723	Map
FL	Research Site	Boca Raton33487	NCT06742723	Map
FL	Research Site	Boynton Beach33435	NCT06742723	Map
FL	Research Site	Crystal River34429	NCT06677060	Map
FL	Research Site	Edgewater32132	NCT06742723	Map
FL	Research Site	Fort Lauderdale33316	NCT06677060	Map
FL	Research Site	Fort Lauderdale33316	NCT06742723	Map
FL	Research Site	Fort Myers33912	NCT06677060	Map
FL	Research Site	Hialeah33012	NCT06677060	Map
FL	Research Site	Hollywood33021	NCT06742723	Map
FL	Research Site	Hollywood33021	NCT07222917	Map
FL	Research Site	Jacksonville32216	NCT06677060	Map
FL	Research Site	Jacksonville Beach32250	NCT06742723	Map
FL	Research Site	Lake City32055	NCT06742723	Map
FL	Research Site	Lakeland33813	NCT06677060	Map
FL	Research Site	Lakeland33805	NCT06742723	Map
FL	Research Site	Melbourne32901	NCT06742723	Map
FL	Research Site	Ocoee34761	NCT06677060	Map
FL	Research Site	Ocoee34761	NCT06742723	Map
FL	Research Site	Orlando32822	NCT06677060	Map
FL	Research Site	Palmetto Bay33157	NCT06677060	Map
FL	Research Site	Port Charlotte33952	NCT06742723	Map
FL	Research Site	Port Charlotte33952	NCT07222917	Map
FL	Research Site	Port Orange32127	NCT06742723	Map
FL	Research Site	Port Orange32127	NCT07222917	Map
FL	Research Site	Riverview33578	NCT06742723	Map
FL	Research Site	Saint Augustine32086	NCT06677060	Map
GA	Research Site	Albany31707	NCT06677060	Map
GA	Research Site	Atlanta30303	NCT06677060	Map
GA	Research Site	Atlanta30328	NCT06742723	Map
GA	Research Site	Atlanta30344	NCT06742723	Map
GA	Research Site	Atlanta30344	NCT07222917	Map
GA	Research Site	Brunswick31520	NCT06742723	Map
GA	Research Site	Canton30114	NCT06677060	Map
GA	Research Site	Columbus31904	NCT06677060	Map
GA	Research Site	Conyers30094	NCT06742723	Map
GA	Research Site	Cordele31015	NCT06677060	Map
GA	Research Site	Decatur30030	NCT06742723	Map
GA	Research Site	Lawrenceville30046	NCT06742723	Map
GA	Research Site	Riverdale30274	NCT06742723	Map
GA	Research Site	Suwanee30024	NCT06677060	Map
GA	Research Site	Woodstock30189	NCT06677060	Map
ID	Research Site	Idaho Falls83404	NCT06677060	Map
IL	Research Site	Champaign61822	NCT06677060	Map
IL	Research Site	Champaign61822	NCT06742723	Map
IL	Research Site	Champaign61822	NCT07222917	Map
IL	Research Site	Chicago60616	NCT06677060	Map
IL	Research Site	Chicago60621	NCT06677060	Map
IL	Research Site	Chicago60631	NCT06677060	Map
IL	Research Site	Gurnee60031	NCT06677060	Map
IL	Research Site	Island Lake60042	NCT06677060	Map
IL	Research Site	Maywood60153	NCT06742723	Map
IL	Research Site	Park Ridge60068	NCT06677060	Map
IL	Research Site	Rockford61107	NCT06742723	Map
IL	Research Site	Springfield62702	NCT07007793	Map
IN	Research Site	Indianapolis46202	NCT06677060	Map
IN	Research Site	Indianapolis46202	NCT06742723	Map
IN	Research Site	Munster46321	NCT06677060	Map
IN	Research Site	Richmond47374	NCT06677060	Map
IN	Research Site	South Bend46617	NCT06677060	Map
IA	Research Site	Iowa City52242	NCT06742723	Map
IA	Research Site	West Des Moines50266	NCT06742723	Map
KS	Research Site	El Dorado67042	NCT06677060	Map
KS	Research Site	Hutchinson67502	NCT06742723	Map
KS	Research Site	Kansas City66112	NCT06742723	Map
KS	Research Site	Lenexa66219	NCT06677060	Map
KS	Research Site	Newton67114	NCT06677060	Map
KS	Research Site	Wichita67214	NCT06742723	Map
KS	Research Site	Wichita67214	NCT07222917	Map
KY	Research Site	Lexington40509	NCT06677060	Map
KY	Research Site	Owensboro42301	NCT06677060	Map
KY	Research Site	Paducah42001	NCT06677060	Map
LA	Research Site	Alexandria71303	NCT06677060	Map
LA	Research Site	Metairie70006	NCT06742723	Map
LA	Research Site	Shreveport71101	NCT06677060	Map
LA	Research Site	West Monroe71291	NCT06742723	Map
MD	Research Site	Baltimore21229	NCT06677060	Map
MD	Research Site	Beltsville20705	NCT06677060	Map
MD	Research Site	Bethesda20889	NCT06742723	Map
MD	Research Site	Lutherville-Timonium21093	NCT06677060	Map
MD	Research Site	Potomac20854	NCT06677060	Map
MA	Research Site	Boston02115	NCT06677060	Map
MA	Research Site	Boston02115	NCT06742723	Map
MA	Research Site	Boston02111	NCT07007793	Map
MA	Research Site	Boston02115	NCT07007793	Map
MA	Research Site	New Bedford02740	NCT06677060	Map
MA	Research Site	New Bedford02740	NCT06742723	Map
MA	Research Site	Roslindale02131	NCT06677060	Map
MA	Research Site	Worcester01608	NCT06742723	Map
MI	Research Site	Ann Arbor48109	NCT06742723	Map
MI	Research Site	Ann Arbor48109	NCT07007793	Map
MI	Research Site	Detroit48202	NCT06742723	Map
MI	Research Site	Farmington Hills48336	NCT06677060	Map
MI	Research Site	Flint48532	NCT06677060	Map
MI	Research Site	Garden City48135	NCT06742723	Map
MI	Research Site	Saint Joseph49085	NCT06742723	Map
MI	Research Site	Troy48098	NCT06677060	Map
MN	Research Site	Mankato56001	NCT06677060	Map
MN	Research Site	Minneapolis55417	NCT06677060	Map
MN	Research Site	Rochester55902	NCT07007793	Map
MS	Research Site	Olive Branch38654	NCT07007793	Map
MO	Research Site	Columbia65201	NCT06677060	Map
MO	Research Site	Kansas City64111	NCT06677060	Map
MO	Research Site	Kansas City64151	NCT06677060	Map
MO	Research Site	Kansas City64111	NCT06742723	Map
MO	Research Site	Kansas City64151	NCT06742723	Map
MO	Research Site	St Louis63136	NCT06677060	Map
MO	Research Site	St Louis63136	NCT06742723	Map
MT	Research Site	Missoula59804	NCT06677060	Map
NE	Research Site	Norfolk68701	NCT06677060	Map
NE	Research Site	Norfolk68701	NCT06742723	Map
NE	Research Site	Omaha68134	NCT06677060	Map
NV	Research Site	Carson City89706	NCT06677060	Map
NJ	Research Site	Eatontown07724	NCT06742723	Map
NJ	Research Site	Eatontown07724	NCT07222917	Map
NJ	Research Site	Pennington08534	NCT06677060	Map
NJ	Research Site	Somerset08873	NCT06677060	Map
NM	Research Site	Albuquerque87102	NCT06677060	Map
NM	Research Site	Albuquerque87108	NCT06677060	Map
NY	Research Site	Albany12208	NCT06677060	Map
NY	Research Site	Albany12205	NCT06742723	Map
NY	Research Site	Brooklyn11201	NCT06677060	Map
NY	Research Site	Brooklyn11220	NCT06677060	Map
NY	Research Site	Buffalo14203	NCT06742723	Map
NY	Research Site	Massapequa11758	NCT06677060	Map
NY	Research Site	New York10016	NCT06742723	Map
NY	Research Site	Queens Village11428	NCT06677060	Map
NC	Research Site	Charlotte28287	NCT06677060	Map
NC	Research Site	Durham27701	NCT06677060	Map
NC	Research Site	Fayetteville28304	NCT06677060	Map
NC	Research Site	Greenville27834	NCT06742723	Map
NC	Research Site	Greenville27834	NCT07222917	Map
NC	Research Site	Hickory28601	NCT06742723	Map
NC	Research Site	Jacksonville28546	NCT06742723	Map
NC	Research Site	Jacksonville28546	NCT07222917	Map
NC	Research Site	Kinston28504	NCT06742723	Map
NC	Research Site	Monroe28112	NCT06677060	Map
NC	Research Site	Morehead City28557	NCT06742723	Map
NC	Research Site	New Bern28562	NCT06677060	Map
NC	Research Site	New Bern28562	NCT06742723	Map
NC	Research Site	New Bern28562	NCT07222917	Map
NC	Research Site	Raleigh27607	NCT06677060	Map
NC	Research Site	Raleigh27609	NCT06742723	Map
NC	Research Site	Rocky Mount27804	NCT06677060	Map
NC	Research Site	Rocky Mount27804	NCT06742723	Map
NC	Research Site	Sanford27330	NCT06742723	Map
NC	Research Site	Statesville28625	NCT06742723	Map
NC	Research Site	Wilmington28401	NCT06742723	Map
NC	Research Site	Wilmington28412	NCT06742723	Map
NC	Research Site	Winston-Salem27103	NCT06742723	Map
ND	Research Site	Fargo58104	NCT06677060	Map
OH	Research Site	Beavercreek45431	NCT06677060	Map
OH	Research Site	Canton44718	NCT06677060	Map
OH	Research Site	Canton44718	NCT06742723	Map
OH	Research Site	Cincinnati45219	NCT06677060	Map
OH	Research Site	Cincinnati45220	NCT06677060	Map
OH	Research Site	Cincinnati45212	NCT06742723	Map
OH	Research Site	Cincinnati45219	NCT06742723	Map
OH	Research Site	Columbus43215	NCT06677060	Map
OH	Research Site	Columbus43210	NCT06742723	Map
OH	Research Site	Columbus43213	NCT06742723	Map
OH	Research Site	Columbus43215	NCT06742723	Map
OH	Research Site	Columbus43210	NCT07007793	Map
OH	Research Site	Columbus43215	NCT07222917	Map
OH	Research Site	Maumee43537	NCT06677060	Map
OK	Research Site	Oklahoma City73111	NCT06677060	Map
OK	Research Site	Oklahoma City73120	NCT06677060	Map
PA	Research Site	Bethlehem18017	NCT07007793	Map
PA	Research Site	Bridgeville15017	NCT06742723	Map
PA	Research Site	Butler16001	NCT06742723	Map
PA	Research Site	Camp Hill17011	NCT06677060	Map
PA	Research Site	Exton19341	NCT06742723	Map
PA	Research Site	Horsham19044	NCT06677060	Map
PA	Research Site	Media19063	NCT06742723	Map
PA	Research Site	Media19063	NCT07222917	Map
PA	Research Site	Philadelphia19114	NCT06677060	Map
PA	Research Site	Scottdale15683	NCT06677060	Map
PA	Research Site	Smithfield15478	NCT06677060	Map
RI	Research Site	East Providence02914	NCT06742723	Map
RI	Research Site	East Providence02915	NCT06742723	Map
RI	Research Site	East Providence02914	NCT07222917	Map
SC	Research Site	Charleston29414	NCT06742723	Map
SC	Research Site	Columbia29203	NCT06742723	Map
SC	Research Site	Columbia29203	NCT07007793	Map
SC	Research Site	Fort Mill29715	NCT06677060	Map
SC	Research Site	Mt. Pleasant29464	NCT06677060	Map
SC	Research Site	North Charleston29405	NCT06677060	Map
SC	Research Site	Spartanburg29301	NCT06677060	Map
TN	Research Site	Chattanooga37421	NCT06742723	Map
TN	Research Site	Cleveland37312	NCT06677060	Map
TN	Research Site	Knoxville37912	NCT06742723	Map
TN	Research Site	Knoxville37938	NCT06742723	Map
TN	Research Site	Morristown37813	NCT06677060	Map
TN	Research Site	Nashville37203	NCT06677060	Map
TN	Research Site	Nashville37232	NCT06742723	Map
TX	Research Site	Arlington76015	NCT06742723	Map
TX	Research Site	Arlington76015	NCT07222917	Map
TX	Research Site	Austin78704	NCT06677060	Map
TX	Research Site	Austin78726	NCT06742723	Map
TX	Research Site	Austin78735	NCT06742723	Map
TX	Research Site	Austin78751	NCT06742723	Map
TX	Research Site	Beaumont77702	NCT06677060	Map
TX	Research Site	Dallas75390-9015	NCT06677060	Map
TX	Research Site	Dallas75234	NCT06742723	Map
TX	Research Site	Dallas75246	NCT06742723	Map
TX	Research Site	Dallas75390	NCT07007793	Map
TX	Research Site	Duncanville75137	NCT06677060	Map
TX	Research Site	Houston77084	NCT06677060	Map
TX	Research Site	Houston77089	NCT06677060	Map
TX	Research Site	Houston77004	NCT06742723	Map
TX	Research Site	Houston77099	NCT06742723	Map
TX	Research Site	Humble77346	NCT06742723	Map
TX	Research Site	McAllen78501	NCT06677060	Map
TX	Research Site	McAllen78503	NCT06677060	Map
TX	Research Site	Mesquite75149	NCT06677060	Map
TX	Research Site	Paris75462	NCT06677060	Map
TX	Research Site	Pasadena77504	NCT06742723	Map
TX	Research Site	Pasadena77504	NCT07222917	Map
TX	Research Site	San Antonio78257	NCT06677060	Map
TX	Research Site	San Antonio78212	NCT06742723	Map
TX	Research Site	San Antonio78212	NCT07222917	Map
TX	Research Site	Stephenville76401	NCT06677060	Map
TX	Research Site	Sugar Land77479	NCT06677060	Map
TX	Research Site	Tomball77375	NCT06677060	Map
TX	Research Site	Weslaco78596	NCT06677060	Map
TX	Research Site	Woodway76712	NCT06677060	Map
UT	Research Site	Clearfield84015	NCT06677060	Map
UT	Research Site	Ogden84405	NCT06677060	Map
UT	Research Site	South Salt Lake84115	NCT06742723	Map
VT	Research Site	Burlington05401	NCT06742723	Map
VA	Research Site	Arlington22205	NCT06742723	Map
VA	Research Site	Burke22015	NCT06677060	Map
VA	Research Site	Charlottesville22911	NCT06677060	Map
VA	Research Site	Falls Church22042	NCT06677060	Map
VA	Research Site	Manassas20110	NCT06742723	Map
VA	Research Site	Midlothian23112	NCT06677060	Map
VA	Research Site	Newport News23606	NCT06742723	Map
VA	Research Site	Norfolk23502	NCT06677060	Map
VA	Research Site	Salem24153	NCT06677060	Map
VA	Research Site	Woodbridge22192	NCT06742723	Map
VA	Research Site	Woodbridge22192	NCT07222917	Map
WA	Research Site	Redmond98052	NCT06677060	Map
WA	Research Site	Renton98057	NCT06677060	Map
WA	Research Site	Seattle98195	NCT06742723	Map
WV	Research Site	Kingwood26537	NCT06677060	Map
WV	Research Site	Morgantown26505	NCT06677060	Map

Baxdrostat clinical trials at a glance: phase × recruitment status

Phase	recruiting	active not recruiting	completed	Total
P1			7	7
P2	1		1	2
P3	3	1	3	7

Recruiting Baxdrostat clinical trials (4)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT ID	Title	Phase	Indication	Enrollment	Started
NCT06742723	BaxDuo-PacificA Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure	P3	Chronic Kidney Disease and Hypertension	5,000	Mar 2025
NCT06677060	Prevent-HFPhase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin	P3	Heart Failure	11,300	Mar 2025
NCT07007793	BaxPAA Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism	P3	Primary Hyperaldosteronism	250	Aug 2025
NCT07222917	BaxDuo-BalticA Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.	P2	Chronic Kidney Disease and Hypertension	218	Dec 2025

Baxdrostat clinical trials by indication

Hypertension (4)

NCT	Acronym	Phase	Status	Title
NCT05966324	—	P1	completed	Baxdrostat Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study in a Japanese Population
NCT05961397	—	P1	completed	Phase 1 PK Study to Evaluate the PK of CIN-107 in Subjects With Hepatic Impairment
NCT05961384	—	P1	completed	Phase 1 Study to Determine the Metabolism and Clearance of Baxdrostat
NCT05963009	—	P1	completed	Baxdrostat Bioavailability and Bioequivalence Study

Chronic Kidney Disease and Hypertension (3)

NCT	Acronym	Phase	Status	Title
NCT06742723	BaxDuo-Pacific	P3	recruiting	A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06268873	—	P3	active not recruiting	A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.
NCT07222917	BaxDuo-Baltic	P2	recruiting	A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.

Healthy Participants (3)

NCT	Acronym	Phase	Status	Title
NCT06657105	—	P1	completed	A Study to Investigate the Pharmacokinetics of Ethinyl Estradiol and Levonorgestrel When Given Alone and in Combination With Baxdrostat in Healthy Females of Non-childbearing Potential
NCT06357520	—	P1	completed	A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy Participants
NCT06194032	—	P1	completed	A Study to Investigate the Effect on QTcF of Baxdrostat Compared With Placebo, Using Moxifloxacin as a Positive Control, in Healthy Participants

Uncontrolled Hypertension (3)

NCT	Acronym	Phase	Status	Title
NCT06344104	BaxAsia	P3	completed	A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension
NCT06034743	BaxHTN	P3	completed	A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension
NCT06336356	ACTH	P2	completed	A Study to Evaluate Cortisol Reserve in Response to Adrenocorticotropic Hormone (ACTH) Stimulation Test Following Baxdrostat Treatment Compared to Placebo in Participants With Uncontrolled Hypertension

Primary Hyperaldosteronism (1)

NCT	Acronym	Phase	Status	Title
NCT07007793	BaxPA	P3	recruiting	A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism

Heart Failure (1)

NCT	Acronym	Phase	Status	Title
NCT06677060	Prevent-HF	P3	recruiting	Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Resistant Hypertension (1)

NCT	Acronym	Phase	Status	Title
NCT06168409	Bax24	P3	completed	A Study to Investigate the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants With Resistant Hypertension

Baxdrostat pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

Acronym	NCT	Phase	Status	Indication	Enrollment	PubMed
BaxDuo-Pacific	NCT06742723	P3	recruiting	Chronic Kidney Disease and Hypertension	5,000	—
Prevent-HF	NCT06677060	P3	recruiting	Heart Failure	11,300	PMID 40913594
BaxPA	NCT07007793	P3	recruiting	Primary Hyperaldosteronism	250	—
BaxAsia	NCT06344104	P3	completed	Uncontrolled Hypertension	326	—
BaxHTN	NCT06034743	P3	completed	Uncontrolled Hypertension	796	PMID 40850955
Bax24	NCT06168409	P3	completed	Resistant Hypertension	218	PMID 41794437
BaxDuo-Baltic	NCT07222917	P2	recruiting	Chronic Kidney Disease and Hypertension	218	—
ACTH	NCT06336356	P2	completed	Uncontrolled Hypertension	48	—

All Baxdrostat trials (16)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT ID	Acronym	Title	Phase	Status	Enrollment	Sponsor	Started
NCT06742723	BaxDuo-Pacific	A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure	P3	recruiting	5,000	AstraZeneca	Mar 2025
NCT06677060	Prevent-HF	Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin	P3	recruiting	11,300	AstraZeneca	Mar 2025
NCT06268873		A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.	P3	active not recruiting	2,554	AstraZeneca	Mar 2024
NCT07007793	BaxPA	A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism	P3	recruiting	250	AstraZeneca	Aug 2025
NCT07222917	BaxDuo-Baltic	A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.	P2	recruiting	218	AstraZeneca	Dec 2025
NCT06344104	BaxAsia	A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension	P3	completed	326	AstraZeneca	Apr 2024
NCT06034743	BaxHTN	A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension	P3	completed	796	AstraZeneca	Nov 2023
NCT06168409	Bax24	A Study to Investigate the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants With Resistant Hypertension	P3	completed	218	AstraZeneca	Mar 2024
NCT06657105		A Study to Investigate the Pharmacokinetics of Ethinyl Estradiol and Levonorgestrel When Given Alone and in Combination With Baxdrostat in Healthy Females of Non-childbearing Potential	P1	completed	22	AstraZeneca	Nov 2024
NCT06336356	ACTH	A Study to Evaluate Cortisol Reserve in Response to Adrenocorticotropic Hormone (ACTH) Stimulation Test Following Baxdrostat Treatment Compared to Placebo in Participants With Uncontrolled Hypertension	P2	completed	48	AstraZeneca	Jun 2024
NCT06357520		A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy Participants	P1	completed	14	AstraZeneca	Apr 2024
NCT06194032		A Study to Investigate the Effect on QTcF of Baxdrostat Compared With Placebo, Using Moxifloxacin as a Positive Control, in Healthy Participants	P1	completed	28	AstraZeneca	Feb 2024
NCT05966324		Baxdrostat Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study in a Japanese Population	P1	completed	41	AstraZeneca	Jul 2022
NCT05961397		Phase 1 PK Study to Evaluate the PK of CIN-107 in Subjects With Hepatic Impairment	P1	completed	20	AstraZeneca	Aug 2021
NCT05961384		Phase 1 Study to Determine the Metabolism and Clearance of Baxdrostat	P1	completed	8	AstraZeneca	Nov 2021
NCT05963009		Baxdrostat Bioavailability and Bioequivalence Study	P1	completed	14	AstraZeneca	Mar 2020

Baxdrostat clinical trials: frequently asked questions

How many Baxdrostat clinical trials are there?: 16 Baxdrostat clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 4 are actively recruiting participants. 11 are marked completed.
Are Baxdrostat clinical trials recruiting in 2026?: Yes — 4 Baxdrostat trials are actively recruiting in 2026, with 285 U.S. sites across 41 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Baxdrostat being studied for?: Baxdrostat is being studied for Hypertension, Healthy Participants, Chronic Kidney Disease and Hypertension, Resistant Hypertension, Uncontrolled Hypertension and 2 more. The trials are grouped by indication on this page.
What phase is Baxdrostat in?: Baxdrostat clinical trials span 7 Phase 3, 2 Phase 2, 7 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Baxdrostat clinical trials?: The lead sponsor across the most Baxdrostat trials is AstraZeneca. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Baxdrostatas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

Last refreshed June 12, 2026.

Related pages on Hipa.ai:

Baxdrostat overview Baxdrostat evidence & publications