Atogepant Clinical Trials (2026): 26 Studies for Episodic Migraine & Chronic Migraine

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: .

26 Atogepant clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 10 indications (including Episodic Migraine & Chronic Migraine) and 15,361 total planned enrollment. 16 Phase 3 Atogepant trials, 2 Phase 4 are listed. 7 Atogepant clinical trials are actively recruiting at 93 U.S. sites across 30 states. Most recent activity: NCT05707949 (Apr 2032).

Where to Participate: All Atogepant Trial Sites in the U.S. (93 sites across 30 states)

Every actively recruiting Atogepanttrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
ALRehabilitation & Neurological Services /ID# 248517Huntsville35805-4046NCT05711394Map
ALRehabilitation and Neurological Services /ID# 270782Huntsville35805NCT06810505Map
ALThe Center for Clinical Trials - Saraland /ID# 271604Saraland36571NCT05711394Map
AZNorthern Arizona HealthcareFlagstaff86001NCT06972056Map
AZMayo Clinic ArizonaPhoenix85054NCT06972056Map
ARPreferred Research Partner, Inc /ID# 270389Little Rock72211NCT06810505Map
ARPreferred Research Partners /ID# 249729Little Rock72211NCT05711394Map
CAAdvanced Research Center /ID# 251381Anaheim92805NCT05711394Map
CAAdvanced Research Center /ID# 270257Anaheim92805NCT06810505Map
CANeuro Pain Research Center /ID# 271048Fresno93710NCT06810505Map
CAAccellacare - Long Beach /ID# 270398Long Beach90807NCT06810505Map
CAAlliance for Research Alliance for Wellness /ID# 248521Long Beach90807NCT05711394Map
CAClinical Research InstituteLos Angeles90048NCT06972056Map
CAUSC KeckLos Angeles90033NCT06972056Map
CAExcell Research /ID# 270258Oceanside92056NCT06810505Map
CAExcell Research, Inc /ID# 247532Oceanside92056NCT05711394Map
CADesert Physicians Medical GroupPalm Springs92262NCT06972056Map
CAThe Neurology GroupPomona91767NCT06972056Map
CALumos Clinical Research Center /ID# 249731San Jose95124-4108NCT05711394Map
CALumos Clinical Research Center /ID# 270582San Jose95124NCT06810505Map
CASunwise Clinical Research /ID# 248529Walnut Creek94596NCT05711394Map
CASunwise Clinical Research /ID# 270431Walnut Creek94596NCT06810505Map
COUniversity of Colorado Anschutz Medical CampusAurora80045NCT06972056Map
FLNorthwest Florida Clinical Research Group, LLC /ID# 251382Gulf Breeze32561-4495NCT05711394Map
FLNorthwest Florida Clinical Research Group, LLC /ID# 270833Gulf Breeze32561NCT06810505Map
FLMemorial HealthcareHollywood33021NCT06972056Map
FLMayo Clinic FloridaJacksonville32066NCT06972056Map
FLApple Med ResearchMiami33126NCT06972056Map
FLMy Preferred Research /ID# 270312Miami33155NCT06810505Map
FLMy Preferred Research LLC /ID# 249720Miami33155NCT05711394Map
FLEncore Medical Research - Weston /ID# 271139Weston33331NCT06810505Map
FLPediatric Neurology & Epilepsy Center Of Central Florida - Winter Park /ID# 275263Winter Park32789NCT06810505Map
GACoastal Georgia Child Neurology /ID# 249733Brunswick31520-1601NCT05711394Map
INDeaconess Midtown Hospital /ID# 270572Evansville47710NCT06810505Map
INDeaconess Clinic - Gateway Health Center /ID# 247589Newburgh47630NCT05711394Map
MAClinical Trials of New EnglandHyde Park02136NCT06972056Map
MIMichigan Headache & Neurological Institute (MHNI) /ID# 247468Ann Arbor48104-5131NCT05711394Map
MIMichigan Headache & Neurological Institute /ID# 270942Ann Arbor48104NCT06810505Map
MNMayo ClinicRochester55905NCT06972056Map
MSProven Endpoints LLC /ID# 258066Ridgeland39157NCT05711394Map
MSProven Endpoints LLC /ID# 270269Ridgeland39157NCT06810505Map
MOWashington University St LouisSt Louis63110NCT06972056Map
NENebraska Medical CenterOmaha68198NCT06972056Map
NECct Research - Papillion Research Center /ID# 270393Papillion68046NCT06810505Map
NECognitive Clinical Trials (CCT) - Papillion /ID# 248536Papillion68046-4131NCT05711394Map
NVAdvanced Research Institute RenoReno89511NCT06972056Map
NHHealthy Perspectives - Innovate Mental Health Services /ID# 270847Nashua03060NCT06810505Map
NJJFK Neuroscience InstituteEdison08820NCT06972056Map
NJGoryeb Childrens Hospital /ID# 249724Morristown07960NCT05711394Map
NYDent Neurologic Institute - Amherst /ID# 248534Amherst14226NCT05711394Map
NYDent Neurologic Institute - Amherst /ID# 270260Amherst14226NCT06810505Map
NYNuvance Health InstituteKingston12401NCT06972056Map
NYNorthwell HealthManhasset11030NCT06972056Map
NYMt Sinai Icahn School of MedicineNew York10029NCT06972056Map
NCHeadache Wellness Center /ID# 251018Greensboro27405NCT05711394Map
NCHeadache Wellness Center /ID# 270568Greensboro27405NCT06810505Map
NCWake Forest University HealthWinston-Salem27157NCT06972056Map
OHCincinnati Childrens Hospital Medical Center /ID# 258070Cincinnati45229NCT05711394Map
OHPatient Priority Clinical Sites, LLC /ID# 247535Cincinnati45215-2123NCT05711394Map
OHOhio State University Wexner Medical CenterColumbus43210NCT06972056Map
OKLynn Institute of Oklahoma City /ID# 247600Oklahoma City73112NCT05711394Map
ORAdvanced Research InstitutePortland97223NCT06972056Map
PAChildren's Hospital of Philadelphia - Main /ID# 258071Philadelphia19104-4319NCT05711394Map
PAUniversity of PennsylvaniaPhiladelphia19107NCT06972056Map
PAFrontier Clinical Research - Scottdale /ID# 270854Scottdale15683NCT06810505Map
PAFrontier Clinical Research - Smithfield /ID# 270849Smithfield15478NCT06810505Map
RIBrown University HealthProvidence02903NCT06972056Map
TNLe Bonheur Children's Hospital /ID# 261084Memphis38103NCT05711394Map
TNAccess Clinical Trials Inc /ID# 270280Nashville37203NCT06810505Map
TNAccess Clinical Trials, Inc. /ID# 248532Nashville37203NCT05711394Map
TNVanderbilt Medical CenterNashville37215NCT06972056Map
TXFutureSearch Trials of Neurology /ID# 247470Austin78731NCT05711394Map
TXUT Health Austin at Dell Children's Neurology Clinic /ID# 264082Austin78723-3079NCT05711394Map
TXUT Health Austin at Dell Childrens Neurology Clinic /ID# 270577Austin78723-3079NCT06810505Map
TX3A Research - East El Paso /ID# 248516El Paso79925-7945NCT05711394Map
TXEarle Research /ID# 248501Friendswood77546NCT05711394Map
TXEarle Research /ID# 270424Houston77058NCT06810505Map
TXDHR Health Headache CenterMcAllen78504NCT06972056Map
TXFamily Psychiatry of The Woodlands /ID# 249727The Woodlands77381NCT05711394Map
TXClinPoint Trials /ID# 248540Waxahachie75165-1430NCT05711394Map
TXClinpoint Trials /ID# 270261Waxahachie75165NCT06810505Map
UTPantheon Clinical Research /ID# 251601Bountiful84010-4968NCT05711394Map
UTPantheon Clinical Research /ID# 270259Bountiful84010NCT06810505Map
UTAlpine Research Organization - Clinton /ID# 276497Clinton84015NCT05711394Map
UTAlpine Research Organization - Clinton /ID# 276527Clinton84015NCT06810505Map
UTAdvanced Research Institute OgdenOgden84405NCT06972056Map
UTHighland Clinical Research /ID# 247590Salt Lake City84124NCT05711394Map
UTHighland Clinical Research /ID# 270281Salt Lake City84124NCT06810505Map
VAOffice of Maria Ona /ID# 249738Franklin23851NCT05711394Map
WVFrontier Clinical Research - Kingwood /ID# 271053Kingwood26537NCT06810505Map
WVWest Virginia UniversityMorgantown26506NCT06972056Map
WIMarshfield Clinic Research InstituteMarshfield54449NCT06972056Map
WIThe Medical College of WisconsinMilwaukee53226NCT06972056Map

Atogepant clinical trials at a glance: phase × recruitment status

Phaserecruitingactive not recruitingenrolling by invitationcompletedunknownTotal
P122
P2/P311
P32311016
P4112
N/A21115

Recruiting Atogepant clinical trials (7)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT05707949KaleidoscopeLong-term Extension Study to Assess Adverse Events of Oral Atogepant Tablets in Pediatric Participants (6 to 17 Years of Age) With MigraineP3Migraine Prophylaxis650Jun 2023
NCT06810505A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 YearsP3Chronic Migraine420Feb 2025
NCT06972056Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison StudyP4Migraine1,335Jul 2025
NCT06603558Atogepant PMSSPost-Marketing Study to Assess the Safety and Effectiveness of Oral Atogepant in Korean Adult Participants for the Prevention of Chronic or Episodic MigraineChronic Migraine3,000Sep 2024
NCT05711394A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic MigraineP3Episodic Migraine450May 2023
NCT06212661Migraine Medication Effects on Urinary SymptomsOveractive Bladder200Apr 2024
NCT06882122ATOMNeurophysiological and Biomolecular Effects of Atogepant in Episodic MigraineMigraine Disorder30Dec 2024

Atogepant clinical trials by indication

Episodic Migraine (7)

NCTAcronymPhaseStatusTitle
NCT05711394P3recruitingA Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine
NCT04686136P3completedA Long-Term Safety and Tolerability Extension Study Evaluating Atogepant for the Prevention of Chronic or Episodic Migraine
NCT05264129TANDEMP4completedStudy to Assess Adverse Events When Ubrogepant Tablets in Combination With Atogepant Tablets Are Used to Treat Adult Participants With Migraine
NCT04740827ELEVATEP3completedAtogepant for Prophylaxis of Migraine in Participants Who Failed Previous Oral Prophylactic Treatments.
NCT03939312P3completedExtension Study to Evaluate the Long-Term Safety and Tolerability of Oral Atogepant for the Prevention of Migraine in Participants With Episodic Migraine
NCT03777059P3completed12-Week Placebo-controlled Study of Atogepant for the Preventive Treatment of Migraine in Participants With Episodic Migraine
NCT03700320P3completedStudy to Evaluate the Safety and Tolerability of Treatment With Atogepant 60 mg Daily for the Prevention of Migraine in Participants With Episodic Migraine

Migraine (6)

NCTAcronymPhaseStatusTitle
NCT06972056P4recruitingComparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study
NCT06241313ATO ACUTEP3active not recruitingStudy of Oral Atogepant Tablets to Assess Safety and Efficacy in Adult Participants With Migraine
NCT05748483ATO-TOPIRAMATEP3active not recruitingComparative Study of Oral Atogepant Versus Oral Topiramate to Assess Adverse Events in Adult Participants With Migraine
NCT06414044STARN/Aactive not recruitingItalian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine Patients
NCT05861427JPN PIVOTALP3completedStudy of Oral Atogepant Tablets to Assess Change in Disease Activity in Adult Japanese Participants With Episodic Migraine
NCT04818515P1completedStudy To Assess Adverse Events and Drug to Drug Interaction of Oral Tablet Atogepant and Ubrogepant in Adult Participants With a History of Migraine

Chronic Migraine (6)

NCTAcronymPhaseStatusTitle
NCT06810505P3recruitingA Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years
NCT06603558Atogepant PMSSN/ArecruitingPost-Marketing Study to Assess the Safety and Effectiveness of Oral Atogepant in Korean Adult Participants for the Prevention of Chronic or Episodic Migraine
NCT05216263ATO-BOTOXP3completedStudy of Oral Atogepant When Added to OnabotulinumtoxinA (BOTOX) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Chronic Migraine
NCT04437433JPN ATO OLEP3completedA Study Evaluating Oral Atogepant for the Prevention of Migraine in Japanese Participants With Chronic or Episodic Migraine
NCT04829747P3completedStudy to Assess Adverse Events (AEs) When Oral Atogepant Tablet is Given to Adult Chinese Participants Who Completed Study 3101-303-002 to Prevent Chronic Migraine
NCT03855137P3completedEfficacy, Safety, and Tolerability of Atogepant for the Prevention of Chronic Migraine

Menstrual Migraine (MM) (1)

NCTAcronymPhaseStatusTitle
NCT06806293ATO MMP3active not recruitingStudy of Oral Atogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

Migraine Disorder (1)

NCTAcronymPhaseStatusTitle
NCT06882122ATOMN/ArecruitingNeurophysiological and Biomolecular Effects of Atogepant in Episodic Migraine

Migraine, Prophylaxis (1)

NCTAcronymPhaseStatusTitle
NCT06136442GIANTN/AunknownAtogepant in Real Life in Italy (GIANT)

Overactive Bladder (1)

NCTAcronymPhaseStatusTitle
NCT06212661N/Aenrolling by invitationMigraine Medication Effects on Urinary Symptoms

Healthy Volunteers (1)

NCTAcronymPhaseStatusTitle
NCT05892757P1completedStudy to Assess Adverse Events and Compare How Oral Ubrogepant and Oral Atogepant Moves Through the Body of Healthy Female Adult Volunteers

Migraine Prophylaxis (1)

NCTAcronymPhaseStatusTitle
NCT05707949KaleidoscopeP3enrolling by invitationLong-term Extension Study to Assess Adverse Events of Oral Atogepant Tablets in Pediatric Participants (6 to 17 Years of Age) With Migraine

Migraine, With or Without Aura (1)

NCTAcronymPhaseStatusTitle
NCT02848326AGN-241689P2/P3completedEfficacy, Safety, and Tolerability of Multiple Dosing Regimens of Oral Atogepant (AGN-241689) in Episodic Migraine Prevention

Atogepant pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

AcronymNCTPhaseStatusIndicationEnrollmentPubMed
TANDEMNCT05264129P4completedEpisodic Migraine263PMID 39569702
KaleidoscopeNCT05707949P3enrolling by invitationMigraine Prophylaxis650
ATO MMNCT06806293P3active not recruitingMenstrual Migraine (MM)468
ATO ACUTENCT06241313P3active not recruitingMigraine1,300PMID 41920093
ATO-TOPIRAMATENCT05748483P3active not recruitingMigraine545
ATO-BOTOXNCT05216263P3completedChronic Migraine75PMID 41944477
JPN PIVOTALNCT05861427P3completedMigraine524PMID 41002192
JPN ATO OLENCT04437433P3completedChronic Migraine186PMID 41814051
ELEVATENCT04740827P3completedEpisodic Migraine315PMID 38364831

All Atogepant trials (26)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT05707949KaleidoscopeLong-term Extension Study to Assess Adverse Events of Oral Atogepant Tablets in Pediatric Participants (6 to 17 Years of Age) With MigraineP3enrolling by invitation650AbbVieJun 2023
NCT06810505A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 YearsP3recruiting420AbbVieFeb 2025
NCT06972056Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison StudyP4recruiting1,335Mayo ClinicJul 2025
NCT06603558Atogepant PMSSPost-Marketing Study to Assess the Safety and Effectiveness of Oral Atogepant in Korean Adult Participants for the Prevention of Chronic or Episodic Migrainerecruiting3,000AbbVieSep 2024
NCT05711394A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic MigraineP3recruiting450AbbVieMay 2023
NCT06806293ATO MMStudy of Oral Atogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual MigraineP3active not recruiting468AbbVieFeb 2025
NCT06212661Migraine Medication Effects on Urinary Symptomsenrolling by invitation200The Cleveland ClinicApr 2024
NCT06241313ATO ACUTEStudy of Oral Atogepant Tablets to Assess Safety and Efficacy in Adult Participants With MigraineP3active not recruiting1,300AbbVieMar 2024
NCT05748483ATO-TOPIRAMATEComparative Study of Oral Atogepant Versus Oral Topiramate to Assess Adverse Events in Adult Participants With MigraineP3active not recruiting545AbbVieOct 2023
NCT06882122ATOMNeurophysiological and Biomolecular Effects of Atogepant in Episodic Migrainerecruiting30IRCCS National Neurological Institute "C. Mondino" FoundationDec 2024
NCT06414044STARItalian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine Patientsactive not recruiting500University of FlorenceMay 2024
NCT04686136A Long-Term Safety and Tolerability Extension Study Evaluating Atogepant for the Prevention of Chronic or Episodic MigraineP3completed596AbbVieFeb 2021
NCT05216263ATO-BOTOXStudy of Oral Atogepant When Added to OnabotulinumtoxinA (BOTOX) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Chronic MigraineP3completed75AbbVieMar 2022
NCT05861427JPN PIVOTALStudy of Oral Atogepant Tablets to Assess Change in Disease Activity in Adult Japanese Participants With Episodic MigraineP3completed524AbbVieJul 2023
NCT06136442GIANTAtogepant in Real Life in Italy (GIANT)unknown500IRCCS San Raffaele RomaApr 2024
NCT04437433JPN ATO OLEA Study Evaluating Oral Atogepant for the Prevention of Migraine in Japanese Participants With Chronic or Episodic MigraineP3completed186AbbVieJun 2020
NCT05892757Study to Assess Adverse Events and Compare How Oral Ubrogepant and Oral Atogepant Moves Through the Body of Healthy Female Adult VolunteersP1completed24AbbVieJul 2023
NCT05264129TANDEMStudy to Assess Adverse Events When Ubrogepant Tablets in Combination With Atogepant Tablets Are Used to Treat Adult Participants With MigraineP4completed263AbbVieMar 2022
NCT04740827ELEVATEAtogepant for Prophylaxis of Migraine in Participants Who Failed Previous Oral Prophylactic Treatments.P3completed315AllerganMar 2021
NCT04829747Study to Assess Adverse Events (AEs) When Oral Atogepant Tablet is Given to Adult Chinese Participants Who Completed Study 3101-303-002 to Prevent Chronic MigraineP3completed3AllerganAug 2021
NCT03855137Efficacy, Safety, and Tolerability of Atogepant for the Prevention of Chronic MigraineP3completed778AllerganMar 2019
NCT04818515Study To Assess Adverse Events and Drug to Drug Interaction of Oral Tablet Atogepant and Ubrogepant in Adult Participants With a History of MigraineP1completed26AbbVieMar 2021
NCT03939312Extension Study to Evaluate the Long-Term Safety and Tolerability of Oral Atogepant for the Prevention of Migraine in Participants With Episodic MigraineP3completed685AllerganMay 2019
NCT0377705912-Week Placebo-controlled Study of Atogepant for the Preventive Treatment of Migraine in Participants With Episodic MigraineP3completed910AllerganDec 2018
NCT03700320Study to Evaluate the Safety and Tolerability of Treatment With Atogepant 60 mg Daily for the Prevention of Migraine in Participants With Episodic MigraineP3completed744AllerganOct 2018
NCT02848326AGN-241689Efficacy, Safety, and Tolerability of Multiple Dosing Regimens of Oral Atogepant (AGN-241689) in Episodic Migraine PreventionP2/P3completed834AllerganSep 2016

Atogepant clinical trials: frequently asked questions

How many Atogepant clinical trials are there?
26 Atogepant clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 7 are actively recruiting participants. 14 are marked completed.
Are Atogepant clinical trials recruiting in 2026?
Yes — 7 Atogepant trials are actively recruiting in 2026, with 93 U.S. sites across 30 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Atogepant being studied for?
Atogepant is being studied for Episodic Migraine, Chronic Migraine, Migraine, Menstrual Migraine (MM), Migraine Disorder and 12 more. The trials are grouped by indication on this page.
What phase is Atogepant in?
Atogepant clinical trials span 2 Phase 4, 16 Phase 3, 2 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Atogepant clinical trials?
The lead sponsor across the most Atogepant trials is AbbVie, with 6 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Atogepantas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

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