Trial results for the "DiaBetter Together" study in young adults with Type 1 Diabetes were posted on ClinicalTrials.gov on 2025-12-16, with 144 participants enrolled. The intervention aimed to support the transition from pediatric to adult diabetes care.
Background
Type 1 Diabetes is a chronic autoimmune condition requiring lifelong management, including insulin therapy. The transition from pediatric to adult healthcare can be a particularly challenging period for young adults with Type 1 Diabetes, often leading to gaps in care, reduced adherence to treatment regimens, and poorer glycemic control. Peer support interventions are explored as a method to provide emotional and practical assistance, helping young adults navigate this critical transition and improve health outcomes.
Trial design
This completed Phase 2 randomized controlled trial, NCT04247620, enrolled 144 young adults with Type 1 Diabetes. The study evaluated the impact of the "DiaBetter Together" intervention, a strengths-based peer support program delivered by trained Peer Mentors. The primary aim was to assess the intervention's effect on glycemic control, with secondary aims including time to first adult care visit, adherence, and psychosocial outcomes over 12 months. Participants were randomized to either the DiaBetter Together Intervention group or a Usual Care group.
Key results
The trial reported key measurements for glycemic control, time to first adult care visit, and diabetes self-management:
- Glycemic Control (HbA1c) (Percentage of HbA1c):
- For the DiaBetter Together Intervention group, mean HbA1c values were 9.1 (Standard Deviation 2.0) and 9.2 (Standard Deviation 2.3).
- For the Usual Care group, mean HbA1c values were 8.5 (Standard Deviation 2.0) and 8.6 (Standard Deviation 1.9).
- A mean HbA1c of 6.5 (Standard Deviation 0.7) was also reported for the Peer Mentors group.
- Time to First Adult Care Visit (month):
- The DiaBetter Together Intervention group had a mean time of 4.7 (Standard Deviation 2.1) months.
- The Usual Care group had a mean time of 7.7 (Standard Deviation 2.9) months.
- Diabetes Self-Management/Adherence (Self-Care Inventory-Updated) (scores on a scale):
- For the DiaBetter Together Intervention group, mean scores were 3.8 (Standard Deviation 0.7) and 4.0 (Standard Deviation 0.7).
- For the Usual Care group, mean scores were 4.0 (Standard Deviation 0.6) and 3.9 (Standard Deviation 0.7).
- A mean score of 4.1 (Standard Deviation 0.5) was also reported for the Peer Mentors group.
What this means
The results suggest that the DiaBetter Together intervention may facilitate an earlier transition to adult diabetes care for young adults with Type 1 Diabetes, with the intervention group experiencing their first adult care visit approximately 3 months sooner than the usual care group. However, the reported glycemic control (HbA1c) values for the intervention group were slightly higher than those in the usual care group, indicating no improvement in this primary outcome. Diabetes self-management and adherence scores were comparable between the intervention and usual care groups. The HbA1c value reported for the Peer Mentors group appears distinct from the patient outcomes and its direct implication for the intervention's efficacy in patients is not immediately clear from the provided data.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT04247620, titled "DiaBetter Together for Young Adults With Type 1 Diabetes", were posted on 2025-12-16 on clinicaltrials.gov.