Trial results for a pilot study evaluating a rehabilitation intervention for Multiple Myeloma were posted on ClinicalTrials.gov on 2025-12-16, showing successful enrollment of 5 participants and 100% completion rates for both assessment and intervention.
Background
Multiple myeloma is a cancer of plasma cells, which are a type of white blood cell found in the bone marrow. The disease can lead to various complications, including bone pain, fatigue, kidney problems, and increased risk of infections. Patients often experience decreased physical functioning and a reduced quality of life due to the disease itself and its treatments. Rehabilitation interventions, such as structured exercise programs, are increasingly recognized for their potential to mitigate these challenges, improve physical capabilities, and enhance overall well-being in individuals living with multiple myeloma.
Trial design
This pilot study, titled "Health Through Activity: A Pilot Study of a Rehabilitation Intervention for People Living With Multiple Myeloma," was completed with an enrollment of 5 participants. The study was conducted without a specified phase (NA) and focused on individuals diagnosed with Multiple Myeloma. The intervention, named Health Through Activity (HTA), involved a six-session, customized rehabilitation exercise regimen designed to reduce challenges associated with decreased physical functioning and quality of life by fostering engagement in meaningful activities. The study aimed to explore the feasibility and initial impact of this structured program.
Key results
The trial results focused on feasibility and participant engagement metrics for the Health Through Activity (HTA) intervention:
- The Rate of Participant Enrollment was 5 Participants.
- The Assessment Completion Rate was 5 Participants.
- The Screening Rate was 11 Participants.
- The Eligibility Rate was 5 Participants.
- The Intervention Completion Rate was 5 Participants.
- Participant Satisfaction was reported for 5 Participants.
- Participant Satisfaction was reported for 3 Participants.
- Participant Satisfaction was reported for 3 Participants.
- Participant Satisfaction was reported for 5 Participants.
- Participant Satisfaction was reported for 5 Participants.
- Participant Satisfaction was reported for 5 Participants.
- Participant Satisfaction was reported for 1 Participant.
What this means
The posted results indicate the successful implementation and high participant engagement in the Health Through Activity pilot study for individuals with Multiple Myeloma. The enrollment of 5 participants, coupled with 100% assessment and intervention completion rates, suggests strong feasibility and acceptance of the rehabilitation program. These findings are crucial for a pilot study, demonstrating that the structured exercise regimen can be delivered effectively and that patients are willing and able to participate fully. While the study's small sample size means it cannot provide definitive efficacy data, the high rates of completion and participant satisfaction metrics suggest a positive reception to the intervention. This successful pilot lays the groundwork for larger, more comprehensive studies to further evaluate the impact of such rehabilitation programs on physical functioning and quality of life in the multiple myeloma population.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT05700747, titled "Health Through Activity: A Pilot Study of a Rehabilitation Intervention for People Living With Multiple Myeloma", were posted on 2025-12-16 on clinicaltrials.gov.