Trial results for a lifestyle intervention aimed at reducing Breast Cancer risk were posted on 2026-04-16. The study reported that 46 participants completed a DXA scan for eligibility.
Background
Breast cancer remains a significant health concern, with various factors contributing to its risk. Research suggests that lifestyle factors, including body composition and inflammation, may play a role in modulating this risk, even in individuals who are considered to be of normal weight. Interventions focused on diet and exercise to decrease body fat in postmenopausal women with elevated risk due to excess body fat are being explored as potential strategies for risk reduction.
Trial design
This trial (NCT04267796), which does not have a specified phase, investigated a lifestyle intervention for the reduction of breast cancer risk. The study, which is currently active but not recruiting, aimed to enroll 40 participants. It focused on women with Breast Carcinoma. The trial design included an intervention group and a waitlist control group.
Key results
The trial reported several key measurements related to feasibility and participant engagement:
- For eligibility, the total number of participants completing a DXA scan was 46.
- In the intervention group, intervention adherence was reported for 17 participants.
- Retention rates were observed for 17 participants in the intervention group and 18 participants in the waitlist control group.
What this means
These results provide insights into the operational aspects of implementing a lifestyle intervention study for breast cancer risk reduction. The reported numbers for eligibility, adherence, and retention indicate the study's ability to engage and retain participants in both the intervention and control arms. Such feasibility data are crucial for informing the design and execution of larger-scale trials investigating lifestyle modifications for disease prevention.
Source
The information for this update was sourced from ClinicalTrials.gov, a public registry of clinical studies. The trial results for NCT04267796, titled "Lifestyle Intervention for the Reduction of Breast Cancer Risk in Normal Weight Women," were posted on 2026-04-16 on clinicaltrials.gov.