RecruitingPhase 1Drug trialA Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)This is an open-label, multicenter, within-participant dose-escalation study examining up to 3 dose levels of DISC-3405 and will assess the safety, tolerability, PK, and PD of DISC 3405 in participants with sickle cell disease.