RecruitingClinical trialLinking Affective Dynamics in Response to Daily Stress to Peripheral Vascular Function in Working Age AdultsThe objective of this proposal is to determine whether heightened negative affective responsivity (NA-R) to daily stressors is related to blunted nitric oxide (NO)-mediated endothelium-dependent dilation (EDD) in working age adults and the extent to which this association is impacted by major depressive disorder (MDD).