RecruitingPhase 2Drug trialA Study of Microbiome Transplantation for the Treatment of Constipation and/or Significant Bloating in Patients With Systemic SclerosisThe purpose of this study is to characterize the intestinal flora in subjects with systemic sclerosis-related constipation and/or significant bloating and to determine safety and trends in improvements in the diversity of colonic microbiome and patient symptoms following the administration of either frozen or lyophilized PRIM-DJ2727 microbiota.