RecruitingPhase 1Drug trialCryoablation and Arterial Infusion of SD-101 in Combination With Durvalumab and TremelimumabThe goal of this Phase 1b clinical trial is to evaluate the safety and efficacy of cryoablation and hepatic arterial administration of SD-101 in participants with advanced hepatocellular carcinoma. After this procedure, participants will be treated with tremelimumab and durvalumab every 4 weeks (STRIDE regimen).