RecruitingPhase 3Drug trialLurbinectedin or in Combination with Irinotecan Versus Topotecan in Patients with Relapsed SCLCMulticenter, open-label, randomized, controlled phase III clinical trial to evaluate and compare the activity and safety of two experimental arms consisting of Lurbinectedin monotherapy or Lurbinectedin + Irinotecan combined therapy versus Topotecan comparator in Small-cell Lung Cancer (SCLC) patients who failed one prior platinum-containing line.