RecruitingPhase 1Drug trialNG-350A Plus Chemoradiotherapy for Locally Advanced Rectal CancerThe FORTRESS trial (NG-350A-03) is an open-label, single-arm, and multicentre trial of NG-350A in combination with chemoradiotherapy (CRT) in adult patients with locally advanced rectal cancer (LARC) and at least one risk factor for local or distant recurrence.