RecruitingEarly Phase 1Drug trialOpen-Label Pilot Study With Crofelemer in Patients With Short Bowel SyndromeThe objectives of this study are to evaluate the efficacy and safety of crofelemer treatment in adults affected by Short Bowel Syndrome (SBS) with an ileostomy on parenteral support (PS) in reducing output or PS needs. Crofelemer will be provided as a powder three times daily for 12 weeks and a 4 week follow up. .