RecruitingPhase 2Drug trialREPotrectinib in ROS1-positive Non-small Cell Lung Cancer Patients With Active Brain mEtastasisREPOSE is a phase II clinical trial exploring the safety and efficacy of repotrectinib in patients with non-small cell lung cancer (NSCLC) characterized by the presence of brain metastasis (BM) and whose tumors have mutated ROS proto-oncogene 1, receptor tyrosine kinase (ROS1) gene.