RecruitingEarly Phase 1Drug trialOral Intradialytic Amino Acid Supplementation to Vitalize End-stage Kidney Disease Patients on HemodialysisThe study will test and compare the efficacy of a single essential amino acid valine with a combination of essential amino acids (EAA) supplement on fatigue, frailty, and cognitive function in end-stage kidney disease (ESKD) patients undergoing hemodialysis (HD) treatment.