Apply to trial NCT05649098

A few quick questions so the study team can decide if you might be a fit.

RecruitingEarly Phase 1Drug trial

Repurposing Dupilumab for Management of Pruritic Genetic Inflammatory Skin Disorders

Severe itch is a common symptom of many genetic skin disorders and leads to a negative impact on patient quality of life. The investigators hypothesize that: a) intervention with dupilumab will improve itch in patients with pruritic genetic inflammatory skin disorders, even those not recognized to be Th2-driven; and b) the administration of dupilumab will be well-tolerated, regardless of underlying genetic skin disorder. The total clinical study duration will be 26 months (104 Weeks). The treatment period will include a 16-week open-label phase and a 20-month long-term extension phase for those who qualify and wish to continue.

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