RecruitingPhase 4Drug trialSafety and Efficacy of ARNI After LVAD ImplanT (SEAL-IT) StudyThe purpose of the study is to evaluate how well tolerated and effective an angiotensin receptor-neprilysin inhibitor (sacubitril-valsartan) is in patients with contemporary durable continuous flow left ventricular assist device (CF-LVAD) implantation compared to usual care oral vasodilator therapy.