RecruitingClinical trialCharacterizing Disease Biology, Treatment and Toxicity in Older Adults With Hepatocellular CarcinomaThis is an observational, prospective cohort study that will recruit a diverse sample of 84 participants with newly diagnosed with unresectable, advanced hepatocellular carcinoma (HCC) at the UT Health Cancer Center in San Antonio. This study uses geriatric assessment tools with participants 65 years and older and collects adverse events and exploratory markers of aging for all participants.