RecruitingPhase 2Drug trialJanus Kinase Inhibition to Prevent Ventilator-induced Diaphragm DysfunctionWe intend, with this study, to prove that blocking the molecular mechanisms whose blockade prevents VIDD in animals, will indeed prevent the development of VIDD in humans as well. We believe that this evidence will serve as the required basis for proceeding with large, ICU-based clinical trial(s) of a drug to prevent VIDD.