RecruitingDrug trialiExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D MutationThis phase I trial studies the best dose and side effects of mesenchymal stromal cells-derived exosomes with KrasG12D siRNA (iExosomes) in treating participants with pancreatic cancer with KrasG12D mutation that has spread to other places in the body. iExosomes may work better at treating pancreatic cancer.